Results 21 to 30 of about 1,564 (279)
Chemical Weapons in the Iran-Iraq War (1980–1988). 2. Combat Use of Chemical Weapons
Вестник войск РХБ защиты, 2023 The Iran-Iraq war (1980–1988) was the result of the geopolitical situation in the Middle East after the Islamic revolution in Iran in 1979. Certain longstanding territorial disputes and the absence of mutually recognized state border between the rivalry ...
M. V. Supotnitskiy +2 more
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Acta Medica, 2010 The ability of newly developed oximes (K347, K628) to reduce tabun-induced acute neurotoxic signs and symptoms was compared with currently available oximes (obidoxime, HI-6) using a functional observational battery.
Jiří Kassa +4 more
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Anticholinergic Drugs – Functional Antidotes for the Treatment of Tabun Intoxication
Acta Medica, 2004 Summary: 1. To study the influence of antidotes on tabun-induced neurotoxicity, the rats were injected intramuscularly with organophosphate tabun (LD50).
Gabriela Krejčová, Jiří Kassa
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Acta Medica, 2002 1. The influence of oximes (pralidoxime, obidoxime, HI-6) and anticholinergic drugs (atropine, benactyzine, biperiden, scopolamine) on the effectiveness of antidotal treatment to eliminate tabun-induced lethal effects was studied in mice. 2.
Jiří Kassa
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Вестник войск РХБ защиты, 2023 The Iran-Iraq war (1980–1988) was the first modern war in which chemical weapons were used. The purpose of this work is to summarize the experience of treating victims, affected by nerve agents. The publications of Iranian authors in different scientific
M. V. Supotnitskiy
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Chemical Weapons in the Iran-Iraq War (1980–1988). 4. The Destruction of Iraqi Chemical Weapons
Вестник войск РХБ защиты, 2020 After the defeat of Iraqi army in Kuwait in February 1991, on April 3, the UN Security Council (UN Security Council) adopted Resolution 687, that «decides that Iraq shall unconditionally accept the destruction, removal, or rendering harmless, under ...
M. V. Supotnitskiy +2 more
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Counteracting poisoning with chemical warfare nerve agents
Arhiv za Higijenu Rada i Toksikologiju, 2020 Phosphylation of the pivotal enzyme acetylcholinesterase (AChE) by nerve agents (NAs) leads to irreversible inhibition of the enzyme and accumulation of neurotransmitter acetylcholine, which induces cholinergic crisis, that is, overstimulation of ...
Hrvat Nikolina Maček, Kovarik Zrinka
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Energetics of Ortho-7 (oxime drug) translocation through the active-site gorge of tabun conjugated acetylcholinesterase. [PDF]
PLoS ONE, 2012 Oxime drugs translocate through the 20 Å active-site gorge of acetylcholinesterase in order to liberate the enzyme from organophosphorus compounds' (such as tabun) conjugation.
Vivek Sinha +2 more
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Chemical Weapons: History of the Study of Organophosphorus Toxic Agents Abroad
Вестник войск РХБ защиты, 2023 Organophosphorus compounds occupy a unique positon among all chemical warfare agents (CWA's). Since the 1930-s their high toxicity, wide range of physical-chemical properties and complex action attracted close attention of foreign military experts.
I. A. Nelga +5 more
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Centrally acting oximes in reactivation of tabun-phosphoramidated AChE [PDF]
Chemico-Biological Interactions, 2013 Organophosphates (OP) inhibit acetylcholinesterase (AChE, EC 3.1.1.7), both in peripheral tissues and central nervous system (CNS), causing adverse and sometimes fatal effects due to the accumulation of neurotransmitter acetylcholine (ACh). The currently used therapy, focusing on the reactivation of inhibited AChE, is limited to peripheral tissues ...
Kovarik, Zrinka +6 more
openaire +3 more sources