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Unraveling the mystery of Tacaribe virus [PDF]

open access: yesmSphere
Tacaribe virus (TCRV) was first isolated in the mid-1950s from several Artibeus species bats in and around Port of Spain, Trinidad and Tobago. Since that time, debate has persisted whether artibeus bats serve as reservoir hosts of the virus or whether ...
Tony Schountz
doaj   +4 more sources

Interaction of silver nanoparticles with Tacaribe virus [PDF]

open access: yesJournal of Nanobiotechnology, 2010
Background Silver nanoparticles possess many unique properties that make them attractive for use in biological applications. Recently they received attention when it was shown that 10 nm silver nanoparticles were bactericidal, which is promising in light
Speshock Janice L   +4 more
doaj   +5 more sources

The Protein Kinase Receptor Modulates the Innate Immune Response against Tacaribe Virus [PDF]

open access: yesViruses, 2021
The New World (NW) mammarenavirus group includes several zoonotic highly pathogenic viruses, such as Junin (JUNV) or Machupo (MACV). Contrary to the Old World mammarenavirus group, these viruses are not able to completely suppress the innate immune ...
Hector Moreno, Stefan Kunz
doaj   +7 more sources

Transcriptomic Signatures of Tacaribe Virus-Infected Jamaican Fruit Bats [PDF]

open access: yesmSphere, 2017
Tacaribe virus (TCRV) is a mammalian arenavirus that was first isolated from artibeus bats in the 1950s. Subsequent experimental infection of Jamaican fruit bats (Artibeus jamaicensis) caused a disease similar to that of naturally infected bats. Although
Diana L. Gerrard   +7 more
doaj   +5 more sources

Development of a Reverse Genetic System to Generate Recombinant Chimeric Tacaribe Virus that Expresses Junín Virus Glycoproteins [PDF]

open access: yesPathogens, 2020
Mammarenaviruses are enveloped and segmented negative-stranded RNA viruses that comprise several pathogenic members associated with severe human hemorrhagic fevers. Tacaribe virus (TCRV) is the prototype for the New World group of mammarenaviruses and is
Sabrina Foscaldi   +5 more
doaj   +6 more sources

Tacaribe virus but not junin virus infection induces cytokine release from primary human monocytes and macrophages. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2011
The mechanisms underlying the development of disease during arenavirus infection are poorly understood. However, common to all hemorrhagic fever diseases is the involvement of macrophages as primary target cells, suggesting that the immune response in ...
Allison Groseth   +6 more
doaj   +5 more sources

Complete genome sequence of Tacaribe virus. [PDF]

open access: yesArch Virol, 2020
AbstractTacaribe virus (TCRV) is the prototype of the New World arenaviruses (also known as TCRV serocomplex viruses). While TCRV is not itself a human pathogen, many closely related members of this group cause hemorrhagic fever, and thus TCRV has long served as an important BSL2 system for research into diverse areas of arenavirus biology.
Holzerland J   +5 more
europepmc   +6 more sources

Highly Diverse Arenaviruses in Neotropical Bats, Brazil [PDF]

open access: yesEmerging Infectious Diseases, 2022
We detected arenavirus RNA in 1.6% of 1,047 bats in Brazil that were sampled during 2007–2011. We identified Tacaribe virus in 2 Artibeus sp. bats and a new arenavirus species in Carollia perspicillata bats that we named Tietê mammarenavirus.
Luiz Gustavo Bentim Góes   +14 more
doaj   +2 more sources

Regulation of Stress-Activated Kinases in Response to Tacaribe Virus Infection and Its Implications for Viral Replication [PDF]

open access: yesViruses, 2022
Arenaviruses include important zoonotic pathogens that cause hemorrhagic fever (e.g., Junín virus; JUNV) as well as other viruses that are closely related but apathogenic (e.g., Tacaribe virus; TCRV).
Julia Holzerland   +2 more
doaj   +2 more sources

Isolation of Tacaribe virus, a Caribbean arenavirus, from host-seeking Amblyomma americanum ticks in Florida. [PDF]

open access: yesPLoS ONE, 2014
Arenaviridae are a family of single stranded RNA viruses of mammals and boid snakes. Twenty-nine distinct mammalian arenaviruses have been identified, many of which cause severe hemorrhagic disease in humans, particularly in parts of sub-Saharan Africa ...
Katherine A Sayler   +6 more
doaj   +2 more sources

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