Results 41 to 50 of about 1,039,970 (161)
The antiviral activity of iota-, kappa-, and lambda-carrageenan against COVID-19: A critical review
Clinical Epidemiology and Global Health, 2021 Objective: There is no specific antiviral treatment available for coronavirus disease 2019 (COVID-19). Among the possible natural constituents is carrageenan, a polymer derived from marine algae that possesses a variety of antiviral properties.
Andri Frediansyah
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The Circular, Segmented Nucleocaspid of an Arenavirus-Tacaribe Virus
Journal of General Virology, 1977 The nucleocapsid structures of Tacaribe virus, a member of the Arenaviridae, were purified from detergent-treated virus particles by equilibrium density gradient centrifugation. Negative-contrast electron microscopy indicated that they were coiled, circular filaments. They had a mean diam.
E L, Palmer +3 more
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Protection Against Junin Virus by Immunization with Live Tacaribe Virus
Experimental Biology and Medicine, 1965 SummaryAdult guinea pigs immunized with the live Tacaribe virus are able to resist challenge with a large dose of Junin virus to which they are normally susceptible. Sera from the Tacaribe virus-immunized guinea pigs contain abundant homologous antibody demonstrable by both complement-fixation and plaque neutralization tests.
N, TAURASO, A, SHELOKOV
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Emerging Microbes and Infections, 2018 Mammarenavirus RNA was detected in Musser’s bristly mouse (Neacomys musseri) from the Amazon region, and this detection indicated that rodents were infected with a novel mammarenavirus, with the proposed name Xapuri virus (XAPV), which is ...
Jorlan Fernandes +11 more
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Animal Models for the Study of Rodent‐Borne Hemorrhagic Fever Viruses: Arenaviruses and Hantaviruses
BioMed Research International, Volume 2015, Issue 1, 2015., 2015 Human pathogenic hantaviruses and arenaviruses are maintained in nature by persistent infection of rodent carrier populations. Several members of these virus groups can cause significant disease in humans that is generically termed viral hemorrhagic fever (HF) and is characterized as a febrile illness with an increased propensity to cause acute ...
Joseph W. Golden +4 more
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Uncovering Viral Protein-Protein Interactions and their Role in Arenavirus Life Cycle
Viruses, 2012 The Arenaviridae family includes widely distributed pathogens that cause severe hemorrhagic fever in humans. Replication and packaging of their single-stranded RNA genome involve RNA recognition by viral proteins and a number of key protein-protein ...
Nora López +3 more
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BioMed Research International, Volume 2014, Issue 1, 2014., 2014 Polyfunctionalized stigmasterol derivatives, (22S,23S)‐22,23‐dihydroxystigmast‐4‐en‐3‐one (compound 1) and (22S,23S)‐3β‐bromo‐5α,22,23‐trihydroxystigmastan‐6‐one (compound 2), inhibit herpes simplex virus type 1 (HSV‐1) replication and spreading in human epithelial cells derived from ocular tissues.
Erina Petrera +3 more
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A potent Lassa virus antiviral targets an arenavirus virulence determinant.
PLoS Pathogens, 2018 Arenaviruses are a significant cause of hemorrhagic fever, an often-fatal disease for which there is no approved antiviral therapy. Lassa fever in particular generates high morbidity and mortality in West Africa, where the disease is endemic, and a ...
Ikenna G Madu +13 more
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Family‐Specific Degenerate Primer Design: A Tool to Design Consensus Degenerated Oligonucleotides
Biotechnology Research International, Volume 2013, Issue 1, 2013., 2013 Designing degenerate PCR primers for templates of unknown nucleotide sequence may be a very difficult task. In this paper, we present a new method to design degenerate primers, implemented in family‐specific degenerate primer design (FAS‐DPD) computer software, for which the starting point is a multiple alignment of related amino acids or nucleotide ...
Javier Alonso Iserte +6 more
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Structural and functional studies of novel mechanisms of Lassa fever virus nucleoprotein in immune suppression, viral RNA transcription and replication [PDF]
, 2013 Lassa fever virus is one of the most dangerous viruses of arenaviridae family, causing more than 500,000 infections per year in Africa. The fatality rate for hospitalized patients is as high as 20%.
Qi, Xiaoxuan
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