Results 51 to 60 of about 1,039,970 (161)
Analysis of the Cell Type-Dependence on the Arenavirus Z-Mediated Virus-Like Particle Production
Several arenaviruses are highly pathogenic to humans, causing hemorrhagic fever. Discovery of anti-arenavirus drug candidates is urgently needed, although the molecular basis of the host- and organ-specific pathogenicity remains to be fully elucidated ...
Patrick I. Mpingabo +6 more
doaj +1 more source
Nanotechnology is a science of producing and utilizing nanosized particles that are measured in nanometers. The unique size‐dependent properties make the nanoparticles superior and indispensable as they show unusual physical, chemical, and properties such as conductivity, heat transfer, melting temperature, optical properties, and magnetization. Taking
Sachindri Rana +5 more
wiley +1 more source
Several arenaviruses cause hemorrhagic fever disease in humans and pose a significant public health concern in their endemic regions. On the other hand, the prototypic arenavirus LCMV is a superb workhorse for the investigation of virus‐host interactions and associated disease.
Shuzo Urata +2 more
wiley +1 more source
Expression and Purification of Z Protein from Junín Virus
Arenaviridae comprises 23 recognized virus species with a bipartite ssRNA genome and an ambisense coding strategy. The virions are enveloped and include nonequimolar amounts of each genomic RNA species, designated L and S, coding for four ORFs (N, GPC, L, and Z).
S. E. Goñi +11 more
wiley +1 more source
Human T-cell Immunoglobulin and Mucin-domain containing proteins (TIM1, 3, and 4) specifically bind phosphatidylserine (PS). TIM1 has been proposed to serve as a cellular receptor for hepatitis A virus and Ebola virus and as an entry factor for dengue ...
Stephanie Jemielity +11 more
doaj +1 more source
This illustration depicts a comprehensive strategy against monkeypox, showcasing its transmission, symptoms, and prevention. Centralized around nanomaterials and biosensors, it integrates early screening, Internet of Things, vaccination, and community involvement through collaboration among healthcare workers, scientists, researchers, social groups ...
Vishal Chaudhary +3 more
wiley +1 more source
The initial events (virus adsorption and fusion with the cells) in the replicative cycle of human immunodeficiency virus (HIV) can serve as targets for the antiviral action of metal‐binding compounds such as polyanionic compounds (polysulfates, polysulfonates, polycarboxylates, polyoxometalates, and sulfonated or carboxylated metalloporphyrins ...
Erik De Clercq
wiley +1 more source
Iniciación y evolución de la infección persistente con virus Tacaribe [PDF]
El virus Tacaribe genera durante su replicación en células Vero partículas interferentes capaces de inhibir a las particulas infectivas interfiriendo con su actividad citolítica y por consiguiente favoreciendo el establecimiento de una infección ...
D'Aiutolo, Ana Cristina
core +2 more sources
Role of the ERK1/2 Signaling Pathway in the Replication of Junín and Tacaribe Viruses
We have previously shown that the infection of cell cultures with the arenaviruses Junín (JUNV), Tacaribe (TCRV), and Pichindé promotes the phosphorylation of mitogen-activated protein kinases (MAPKs) extracellular signal-regulated kinases ...
Jesús E. Brunetti +5 more
doaj +1 more source
Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review
Silver nanoparticles (AgNPs) exhibit broad‐spectrum antiviral activity by targeting key viral structures and processes. They disrupt viral envelopes, compromising integrity, and bind to nucleocapsids, impairing viral replication. AgNPs also inhibit glycoprotein interactions, preventing viral attachment and entry into host cells.
Ekaterine Mosidze +8 more
wiley +1 more source

