Results 31 to 40 of about 1,039,970 (161)
New thiopyrano[2,3-d][1,3]thiazole derivatives as potential antiviral agents [PDF]
The Ukrainian Biochemical Journal, 2016 A series of novel thiopyrano[2,3-d][1,3]thiazole derivatives were synthesized and evaluated for their antiviral activity in vitro within AACF NIAID programme.
N. I. Zelisko +2 more
doaj +1 more source
Generation of Reporter-Expressing New World Arenaviruses: A Systematic Comparison
Viruses, 2022 Replication-competent reporter-expressing viruses are crucial tools in molecular virology with applications that range from antiviral screening to live-cell imaging of protein spatiotemporal dynamics.
Lucie Fénéant +3 more
doaj +1 more source
Novel Arenavirus Infection in Humans, United States
Emerging Infectious Diseases, 2011 Immunoglobulin G against Whitewater Arroyo virus or lymphocytic choriomeningitis virus was found in 41 (3.5%) of 1,185 persons in the United States who had acute central nervous system disease or undifferentiated febrile illnesses.
Mary Louise Milazzo +2 more
doaj +1 more source
Mediators of Inflammation, Volume 2020, Issue 1, 2020., 2020 The immunopathology of chlamydial diseases is exacerbated by a broad‐spectrum of inflammatory mediators, which we reported are inhibited by IL‐10 in macrophages. However, the chlamydial protein moiety that induces the inflammatory mediators and the mechanisms by which IL‐10 inhibits them are unknown.
Skyla A. Duncan +5 more
wiley +1 more source
HBV Core Promoter Inhibition by Tubulin Polymerization Inhibitor (SRI‐32007)
Advances in Virology, Volume 2020, Issue 1, 2020., 2020 Approximately 257 million people chronically infected with hepatitis B virus (HBV) worldwide are at risk of developing hepatocellular carcinoma (HCC). However, despite the availability of potent nucleoside/tide inhibitors, currently there are no curative therapies for chronic HBV infections. To identify potential new antiviral molecules, a select group
Raj Kalkeri +6 more
wiley +1 more source
PLoS Pathogens, 2023 The arenavirus nucleoprotein (NP) plays an important role in the virus' ability to block interferon (IFN) production, and its exonuclease function appears to contribute to this activity.
Patrick Bohn +6 more
doaj +2 more sources
PLoS Pathogens, 2021 Signal-regulatory protein alpha (SIRPA) is a well-known inhibitor of phagocytosis when it complexes with CD47 expressed on target cells. Here we show that SIRPA decreased in vitro infection by a number of pathogenic viruses, including New World and Old ...
Nicolás Sarute +6 more
doaj +1 more source
Different but Not Unique: Deciphering the Immunity of the Jamaican Fruit Bat by Studying Its Viriome
Viruses, 2022 A specialized and fine-tuned immune response of bats upon infection with viruses is believed to provide the basis for a “friendly” coexistence with these pathogens, which are often lethal for humans and other mammals.
Quinnlan David +3 more
doaj +1 more source
Transcriptome sequencing and annotation for the Jamaican fruit bat (Artibeus jamaicensis).
PLoS ONE, 2012 The Jamaican fruit bat (Artibeus jamaicensis) is one of the most common bats in the tropical Americas. It is thought to be a potential reservoir host of Tacaribe virus, an arenavirus closely related to the South American hemorrhagic fever viruses.
Timothy I Shaw +7 more
doaj +1 more source
Effect of Antilymphocyte Serium on Tacaribe Virus Infection in Infant Mice [PDF]
Infection and Immunity, 1971 Tacaribe virus, a member of the arenovirus group, was demonstrated to have similarities in pathogenesis to the prototype virus of this group, lymphocytic choriomeningitis (LCM) virus. Treatment with antilymphocyte serum (ALS) doubled the survival time of mice neonatally infected with a lethal dose of Tacaribe virus.
E C, Borden +3 more
openaire +2 more sources