Results 61 to 70 of about 1,039,970 (161)
WIREs RNA, Volume 16, Issue 2, March/April 2025.Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus +3 more
wiley +1 more source
Sequence identity of the Florida isolate of Tacaribe virus and the prototype virus.
, 2014 Sequence identity of the Florida isolate of Tacaribe virus and the prototype virus.
Anthony F. Barbet (324450) +6 more
core +1 more source
Identification and characterization of a novel non-structural protein of bluetongue virus [PDF]
, 2011 Bluetongue virus (BTV) is the causative agent of a major disease of livestock (bluetongue). For over two decades, it has been widely accepted that the 10 segments of the dsRNA genome of BTV encode for 7 structural and 3 non-structural proteins.
Rixon, F. +43 more
core +1 more source
TRIM2, a novel member of the antiviral family, limits New World arenavirus entry.
PLoS Biology, 2019 Tripartite motif (TRIM) proteins belong to a large family with many roles in host biology, including restricting virus infection. Here, we found that TRIM2, which has been implicated in cases of Charcot-Marie-Tooth disease (CMTD) in humans, acts by ...
Nicolas Sarute +9 more
doaj +1 more source
Analysis of the Glycoprotein Gene of Tacaribe Virus and Neutralization-resistant Variants
Journal of General Virology, 1991 We have previously generated neutralization-resistant variants of Tacaribe virus in the presence of a monoclonal antibody (MAb) specific for the envelope glycoprotein. The envelope glycoprotein precursor (GPC) genes of two variant viruses were sequenced following polymerase chain reaction amplification of a specific region of the Tacaribe virus S RNA ...
L M, Allison +3 more
openaire +2 more sources
, 2019 (A) LD50 study with F425L (n = 6 per group). (B) LD50 study with Tacaribe virus (n = 6 per group). (C) Mice (n = 5) infected with F425L (2,000 PFU) were challenged 31 days later with wild-type Tacaribe virus (200 PFU). Age-matched naïve mice (n = 6) were
Megan Files (1523566) +13 more
core +1 more source
Modulation of the Host Response to Tacaribe Arenavirus Infection in AG129 Mice by MY-24 [PDF]
, 2012 MY-24 is a new antiviral compound recently shown to protect immunocompromised mice from lethal challenge with Tacaribe virus (TCRV). Tacaribe virus is incapable of causing disease to humans, but is closely related to the highly pathogenic New World ...
Sefing, Eric
core +1 more source
Results in ChemistryBackground: Yellow Fever Virus (YFV) and the Tacaribe virus complex are significant viral pathogens that pose severe public health risks, particularly in tropical regions of the Americas.
Anatolii Demchenko +10 more
doaj +1 more source
The Phylogeny of New World (Tacaribe Complex) Arenaviruses [PDF]
, 1996 Several New World (Tacaribe complex) arenaviruses (Arenaviridae) are known to cause severe hemorrhagic disease in humans. Phylogenetic reconstruction of the Tacaribe complex arenaviruses previously has been limited by the relative scarcity of sequence ...
NICHOL, STUART T. +2 more
core +1 more source
LHF-535 protects AG129 mice against lethal Tacaribe virus challenge.
, 2019 Mice were challenged with 200 plaque-forming units (PFU) of Tacaribe virus by intraperitoneal injection. Mice received daily oral doses of LHF-535 (3, 10, or 30 mg/kg) or vehicle alone beginning 0.5 h prior to challenge until 13 days post-challenge.
Megan Files (1523566) +13 more
core +1 more source