Results 61 to 70 of about 1,817 (181)

Human transferrin receptor triggers an alternative Tacaribe virus internalization pathway

Archives of Virology, 2015
Tacaribe virus (TCRV) entry occurs by receptor-mediated endocytosis. To explore the entry mechanism used by TCRV, the inhibitory effects of drugs and dominant negative (DN) constructions affecting the main endocytic pathways were analyzed. In cells lacking the human transferrin receptor (hTfR), compounds and DN proteins that impair clathrin-mediated ...
Roldan, Julieta Suyay, Martinez, Maria g., Forlenza, María Belén Forlenza, Whittaker, Gary R., Candurra, Nélida Alicia   +4 more
openaire   +3 more sources

Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review

Global Challenges, Volume 9, Issue 5, May 2025.
Silver nanoparticles (AgNPs) exhibit broad‐spectrum antiviral activity by targeting key viral structures and processes. They disrupt viral envelopes, compromising integrity, and bind to nucleocapsids, impairing viral replication. AgNPs also inhibit glycoprotein interactions, preventing viral attachment and entry into host cells.
Ekaterine Mosidze, Gianluigi Franci, Federica Dell'Annunziata, Nicoletta Capuano, Marica Colella, Flora Salzano, Massimiliano Galdiero, Aliosha Bakuridze, Veronica Folliero   +8 more
wiley   +1 more source

Two Birds With One Stone: RNA Virus Strategies to Manipulate G3BP1 and Other Stress Granule Components

WIREs RNA, Volume 16, Issue 2, March/April 2025.
Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus, Eliana Dukhno, Rupali Kapoor, Piotr Gerlach   +3 more
wiley   +1 more source

Viral Takeover of the Host Ubiquitin System [PDF]

, 2011
Like the other more well-characterized post-translational modifications (phosphorylation, methylation, acetylation, acylation, etc.), the attachment of the 76 amino acid ubiquitin (Ub) protein to substrates has been shown to govern countless cellular ...
Jean K. Gustin, Ashlee V. Moses, Klaus Früh, Janet L. Douglas   +3 more
core   +1 more source

Silver nanoparticles are broad-spectrum bactericidal and virucidal compounds [PDF]

, 2011
The advance in nanotechnology has enabled us to utilize particles in the size of the nanoscale. This has created new therapeutic horizons, and in the case of silver, the currently available data only reveals the surface of the potential benefits and the ...
Dinesh K Singh, Elsa N Garza-Treviño, Humberto H Lara, Liliana Ixtepan-Turrent   +3 more
core   +3 more sources

Cross-Protection between Tacaribe Complex Viruses. Presence of Neutralizing Antibodies against Junin Virus (Argentine Hemorrhagic Fever) in Guinea Pigs Infected with Tacaribe Virus

Intervirology, 1975
Cross-protection between Junin virus and five other Tacaribe complex viruses and the serological response of guinea pigs inoculated with Tacaribe virus are reported here. Previous infection with Tamiami or Pichinde viruses significantly delayed guinea pig deaths.
M C, Weissenbacher, C E, Coto, M A, Calello   +2 more
openaire   +2 more sources

Synthesis and evaluation of the antiviral activity of 2-(dichloromethyl)pyrazolo[1,5-a][1,3,5]triazines

Доповiдi Нацiональної академiї наук України, 2019
It is found that N-(2,2-dichloro-1-cyanoethenyl)carboxamides react with 1H-pyrazol-5-amines in the presence of triethylamine to give 2-(dichloromethyl)pyrazolo[1,5-a][1,3,5]triazines. Apparently, this cyclocondensation con sists of the following steps: a)
Ye.S. Velihina, S.G. Pil’o, V.S. Zyabrev, V.S. Brovarets   +3 more
doaj   +1 more source

VIPR: a probabilistic algorithm for analysis of microbial detection microarrays [PDF]

, 2010
Background All infectious disease oriented clinical diagnostic assays in use today focus on detecting the presence of a single, well defined target agent or a set of agents.
Adam F Allred, David Wang, Guang Wu, Kael F Fischer, Michael R Holbrook, Robert B Tesh, Tuya Wulan   +6 more
core   +2 more sources

Pluripotent human embryonic stem cell derived neural lineages for in vitro modelling of enterovirus 71 infection and therapy [PDF]

, 2016
The incidence of neurological complications and fatalities associated with Hand, Foot & Mouth disease has increased over recent years, due to emergence of newly-evolved strains of Enterovirus 71 (EV71).
Heng, Alexis Boon Chin *, Lim, Lee Wei, Lim, Wei Ling *, Othman, Lekhsan, Poh, Chit Laa *, Richards, Mark, Tan, Kuan Onn *, Tang, Yin Quan *, Yap, May Shin *, Yeo, Yin *   +9 more
core   +1 more source

Analysis of the Glycoprotein Gene of Tacaribe Virus and Neutralization-resistant Variants

Journal of General Virology, 1991
We have previously generated neutralization-resistant variants of Tacaribe virus in the presence of a monoclonal antibody (MAb) specific for the envelope glycoprotein. The envelope glycoprotein precursor (GPC) genes of two variant viruses were sequenced following polymerase chain reaction amplification of a specific region of the Tacaribe virus S RNA ...
L M, Allison, M W, Salter, S, Kiguwa, C R, Howard   +3 more
openaire   +2 more sources