Genetic Evidence for a Tacaribe Serocomplex Virus, Mexico
Emerging Infectious Diseases, 2010 We isolated arenavirus RNA from white-toothed woodrats (Neotoma leucodon) captured in a region of Mexico in which woodrats are food for humans. Analyses of nucleotide and amino acid sequence data indicated that the woodrats were infected with a novel ...
Catherine C. Inizan +5 more
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Development of Reverse Genetics for the Prototype New World Mammarenavirus Tacaribe Virus. [PDF]
J Virol, 2020 To date, no Food and Drug Administration (FDA)-approved vaccines are available to combat hemorrhagic fever caused by mammarenavirus infections in humans. Treatment of mammarenavirus infections is limited to the off-label use of ribavirin, which is partially effective and associated with significant side effects.
Ye C +2 more
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Integrated molecular and metatranscriptomic evidence of Tacaribe virus and the brain virome profile of Molossus molossus bat sampled in Brazil [PDF]
Microbiology SpectrumTacaribe virus (TCRV), a New World arenavirus, is associated with neotropical frugivorous bats, particularly Artibeus spp., and is considered to have zoonotic potential.
Larissa Leão F. de Sousa +11 more
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BH3-only sensors Bad, Noxa and Puma are Key Regulators of Tacaribe virus-induced Apoptosis. [PDF]
PLoS Pathogens, 2020 Pathogenicity often differs dramatically among even closely related arenavirus species. For instance, Junín virus (JUNV), the causative agent of Argentine hemorrhagic fever (AHF), is closely related to Tacaribe virus (TCRV), which is normally avirulent ...
Julia Holzerland +5 more
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Discovery and biological confirmation of a highly divergent Tacaribe virus in metatranscriptomic data from neotropical bats [PDF]
mSphereFirst isolated from neotropical fruit bats in Trinidad in 1956, Tacaribe virus (TCRV) has rarely been detected since. We searched for New World arenavirus reads in roughly 5.7 million sequencing runs available on public databases using Serratus.
Carlo Fischer +8 more
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Molecular characterization of arenavirus defective viral genomes reveals sequence features associated with their formation [PDF]
Journal of VirologyDefective viral genomes (DVGs) are byproducts of replication that arise during infection with diverse RNA viruses and can impact virus infection and disease outcome.
Thomas Hoenen +5 more
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Efficient budding of the tacaribe virus matrix protein z requires the nucleoprotein. [PDF]
J Virol, 2010 ABSTRACT The Z protein has been shown for several arenaviruses to serve as the viral matrix protein. As such, Z provides the principal force for the budding of virus particles and is capable of forming virus-like particles (VLPs) when expressed alone.
Groseth A +4 more
europepmc +4 more sources
Addressing the Silent Spread of Monkeypox Disease with Advanced Analytical Tools
Small, Volume 19, Issue 9, March 1, 2023., 2023 The work discusses analytical technologies and presents opportunities & challenges to address the silent spread of monkeypox virus. Abstract Monkeypox disease is caused by a virus which belongs to the orthopoxvirus genus of the poxviridae family. This disease has recently spread out to several non‐endemic countries. While some cases have been linked to
Nikhil Bhalla, Amir Farokh Payam
wiley +1 more source
Trends in Bacterial Pathogens of Bats: Global Distribution and Knowledge Gaps
Transboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023 Bats have received considerable recent attention for infectious disease research because of their potential to host and transmit viruses, including Ebola, Hendra, Nipah, and multiple coronaviruses. These pathogens are occasionally transmitted from bats to wildlife, livestock, and to humans, directly or through other bridging (intermediate) hosts.
Tamara Szentivanyi +4 more
wiley +1 more source
BioMed Research International, Volume 2022, Issue 1, 2022., 2022 Increasing outbreaks of new pathogenic viruses have promoted the exploration of novel alternatives to time‐consuming vaccines. Thus, it is necessary to develop a universal approach to halt the spread of new and unknown viruses as they are discovered. One such promising approach is to target lipid membranes, which are common to all viruses and bacteria.
Palayakotai R. Raghavan +1 more
wiley +1 more source