Results 41 to 50 of about 1,050 (148)

Antiviral Action of Synthetic Stigmasterol Derivatives on Herpes Simplex Virus Replication in Nervous Cells In Vitro

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
Polyfunctionalized stigmasterol derivatives, (22S,23S)‐22,23‐dihydroxystigmast‐4‐en‐3‐one (compound 1) and (22S,23S)‐3β‐bromo‐5α,22,23‐trihydroxystigmastan‐6‐one (compound 2), inhibit herpes simplex virus type 1 (HSV‐1) replication and spreading in human epithelial cells derived from ocular tissues.
Erina Petrera, Analía G. Níttolo, Laura E. Alché, Fumio Imazeki   +3 more
wiley   +1 more source

Properties and Characterization of Monoclonal Antibodies to Tacaribe Virus

Journal of General Virology, 1985
Monoclonal antibodies prepared against Tacaribe and Junin viruses have been used to define further the serological relationships between arenaviruses of the Tacaribe complex. A close relationship was found between these two viruses and the heterologous Amapari and Machupo viruses, with Pichinde virus and Parana virus being more distantly related. Among
C R, Howard, H, Lewicki, L, Allison, M, Salter, M J, Buchmeier   +4 more
openaire   +2 more sources

Family‐Specific Degenerate Primer Design: A Tool to Design Consensus Degenerated Oligonucleotides

Biotechnology Research International, Volume 2013, Issue 1, 2013., 2013
Designing degenerate PCR primers for templates of unknown nucleotide sequence may be a very difficult task. In this paper, we present a new method to design degenerate primers, implemented in family‐specific degenerate primer design (FAS‐DPD) computer software, for which the starting point is a multiple alignment of related amino acids or nucleotide ...
Javier Alonso Iserte, Betina Ines Stephan, Sandra Elizabeth Goñi, Cristina Silvia Borio, Pablo Daniel Ghiringhelli, Mario Enrique Lozano, Goetz Laible   +6 more
wiley   +1 more source

The Circular, Segmented Nucleocaspid of an Arenavirus-Tacaribe Virus

Journal of General Virology, 1977
The nucleocapsid structures of Tacaribe virus, a member of the Arenaviridae, were purified from detergent-treated virus particles by equilibrium density gradient centrifugation. Negative-contrast electron microscopy indicated that they were coiled, circular filaments. They had a mean diam.
E L, Palmer, J F, Obijeski, P A, Webb, K M, Johnson   +3 more
openaire   +2 more sources

Ecotoxicity of Nanoparticles

International Scholarly Research Notices, Volume 2013, Issue 1, 2013., 2013
Nanotechnology is a science of producing and utilizing nanosized particles that are measured in nanometers. The unique size‐dependent properties make the nanoparticles superior and indispensable as they show unusual physical, chemical, and properties such as conductivity, heat transfer, melting temperature, optical properties, and magnetization. Taking
Sachindri Rana, P. T. Kalaichelvan, S. C. Bondy, S. K. Brar, J. V. Rogers, B. Zhou   +5 more
wiley   +1 more source

TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine.

PLoS Pathogens, 2013
Human T-cell Immunoglobulin and Mucin-domain containing proteins (TIM1, 3, and 4) specifically bind phosphatidylserine (PS). TIM1 has been proposed to serve as a cellular receptor for hepatitis A virus and Ebola virus and as an entry factor for dengue ...
Stephanie Jemielity, Jinyize J Wang, Ying Kai Chan, Asim A Ahmed, Wenhui Li, Sheena Monahan, Xia Bu, Michael Farzan, Gordon J Freeman, Dale T Umetsu, Rosemarie H Dekruyff, Hyeryun Choe   +11 more
doaj   +1 more source

Serological Relationship of the Tacaribe Complex of Viruses to Lymphocytic Choriomeningitis Virus [PDF]

Journal of Virology, 1970
By means of the indirect fluorescent-antibody test, cross serological reactivity was demonstrated between lymphocytic choriomeningitis (LCM) virus and the viruses of the Tacaribe complex. Antisera to all members of the Tacaribe complex reacted with LCM virus; LCM antisera gave significant staining of Amapari virus, but minimal or inconsistent reactions
W P, Rowe, W E, Pugh, P A, Webb, C J, Peters   +3 more
openaire   +2 more sources

Arenavirus Budding

Advances in Virology, Volume 2011, Issue 1, 2011., 2011
Several arenaviruses cause hemorrhagic fever disease in humans and pose a significant public health concern in their endemic regions. On the other hand, the prototypic arenavirus LCMV is a superb workhorse for the investigation of virus‐host interactions and associated disease.
Shuzo Urata, Juan Carlos de la Torre, Fadila Bouamr   +2 more
wiley   +1 more source

Role of the ERK1/2 Signaling Pathway in the Replication of Junín and Tacaribe Viruses

Viruses, 2018
We have previously shown that the infection of cell cultures with the arenaviruses Junín (JUNV), Tacaribe (TCRV), and Pichindé promotes the phosphorylation of mitogen-activated protein kinases (MAPKs) extracellular signal-regulated kinases ...
Jesús E. Brunetti, Sabrina Foscaldi, Verónica M. Quintana, Luis A. Scolaro, Nora López, Viviana Castilla   +5 more
doaj   +1 more source

Expression and Purification of Z Protein from Junín Virus

BioMed Research International, Volume 2010, Issue 1, 2010., 2010
Arenaviridae comprises 23 recognized virus species with a bipartite ssRNA genome and an ambisense coding strategy. The virions are enveloped and include nonequimolar amounts of each genomic RNA species, designated L and S, coding for four ORFs (N, GPC, L, and Z).
S. E. Goñi, C. S. Borio, F. B. Romano, R. P. Rota, M. G. Pilloff, J. A. Iserte, M. A. Tortorici, B. I. Stephan, M. F. Bilen, P. D. Ghiringhelli, M. E. Lozano, Norbert K. Herzog   +11 more
wiley   +1 more source