Results 51 to 60 of about 1,050 (148)

Interdisciplinary Approach to Monkeypox Prevention: Integrating Nanobiosensors, Nanovaccines, Artificial Intelligence, Visual Arts, and Social Sciences

Small Structures, Volume 6, Issue 7, July 2025.
This illustration depicts a comprehensive strategy against monkeypox, showcasing its transmission, symptoms, and prevention. Centralized around nanomaterials and biosensors, it integrates early screening, Internet of Things, vaccination, and community involvement through collaboration among healthcare workers, scientists, researchers, social groups ...
Vishal Chaudhary, Lucky Lucky, Harsh Sable, Nikhil Bhalla   +3 more
wiley   +1 more source

Antiviral Metal Complexes

Metal-Based Drugs, Volume 4, Issue 3, Page 173-192, 1997., 1997
The initial events (virus adsorption and fusion with the cells) in the replicative cycle of human immunodeficiency virus (HIV) can serve as targets for the antiviral action of metal‐binding compounds such as polyanionic compounds (polysulfates, polysulfonates, polycarboxylates, polyoxometalates, and sulfonated or carboxylated metalloporphyrins ...
Erik De Clercq
wiley   +1 more source

Human transferrin receptor triggers an alternative Tacaribe virus internalization pathway

Archives of Virology, 2015
Tacaribe virus (TCRV) entry occurs by receptor-mediated endocytosis. To explore the entry mechanism used by TCRV, the inhibitory effects of drugs and dominant negative (DN) constructions affecting the main endocytic pathways were analyzed. In cells lacking the human transferrin receptor (hTfR), compounds and DN proteins that impair clathrin-mediated ...
Roldan, Julieta Suyay, Martinez, Maria g., Forlenza, María Belén Forlenza, Whittaker, Gary R., Candurra, Nélida Alicia   +4 more
openaire   +3 more sources

Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review

Global Challenges, Volume 9, Issue 5, May 2025.
Silver nanoparticles (AgNPs) exhibit broad‐spectrum antiviral activity by targeting key viral structures and processes. They disrupt viral envelopes, compromising integrity, and bind to nucleocapsids, impairing viral replication. AgNPs also inhibit glycoprotein interactions, preventing viral attachment and entry into host cells.
Ekaterine Mosidze, Gianluigi Franci, Federica Dell'Annunziata, Nicoletta Capuano, Marica Colella, Flora Salzano, Massimiliano Galdiero, Aliosha Bakuridze, Veronica Folliero   +8 more
wiley   +1 more source

TRIM2, a novel member of the antiviral family, limits New World arenavirus entry.

PLoS Biology, 2019
Tripartite motif (TRIM) proteins belong to a large family with many roles in host biology, including restricting virus infection. Here, we found that TRIM2, which has been implicated in cases of Charcot-Marie-Tooth disease (CMTD) in humans, acts by ...
Nicolas Sarute, Nouhou Ibrahim, Bani Medegan Fagla, Madakasira Lavanya, Christian Cuevas, Spyridon Stavrou, Guliz Otkiran-Clare, Henna Tyynismaa, Jorge Henao-Mejia, Susan R Ross   +9 more
doaj   +1 more source

Two Birds With One Stone: RNA Virus Strategies to Manipulate G3BP1 and Other Stress Granule Components

WIREs RNA, Volume 16, Issue 2, March/April 2025.
Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus, Eliana Dukhno, Rupali Kapoor, Piotr Gerlach   +3 more
wiley   +1 more source

Cross-Protection between Tacaribe Complex Viruses. Presence of Neutralizing Antibodies against Junin Virus (Argentine Hemorrhagic Fever) in Guinea Pigs Infected with Tacaribe Virus

Intervirology, 1975
Cross-protection between Junin virus and five other Tacaribe complex viruses and the serological response of guinea pigs inoculated with Tacaribe virus are reported here. Previous infection with Tamiami or Pichinde viruses significantly delayed guinea pig deaths.
M C, Weissenbacher, C E, Coto, M A, Calello   +2 more
openaire   +2 more sources

Synthesis and evaluation of the antiviral activity of 2-(dichloromethyl)pyrazolo[1,5-a][1,3,5]triazines

Доповiдi Нацiональної академiї наук України, 2019
It is found that N-(2,2-dichloro-1-cyanoethenyl)carboxamides react with 1H-pyrazol-5-amines in the presence of triethylamine to give 2-(dichloromethyl)pyrazolo[1,5-a][1,3,5]triazines. Apparently, this cyclocondensation con sists of the following steps: a)
Ye.S. Velihina, S.G. Pil’o, V.S. Zyabrev, V.S. Brovarets   +3 more
doaj   +1 more source

Analysis of the Glycoprotein Gene of Tacaribe Virus and Neutralization-resistant Variants

Journal of General Virology, 1991
We have previously generated neutralization-resistant variants of Tacaribe virus in the presence of a monoclonal antibody (MAb) specific for the envelope glycoprotein. The envelope glycoprotein precursor (GPC) genes of two variant viruses were sequenced following polymerase chain reaction amplification of a specific region of the Tacaribe virus S RNA ...
L M, Allison, M W, Salter, S, Kiguwa, C R, Howard   +3 more
openaire   +2 more sources

A novel circulating tamiami mammarenavirus shows potential for zoonotic spillover.

PLoS Neglected Tropical Diseases, 2020
A detailed understanding of the mechanisms underlying the capacity of a virus to break the species barrier is crucial for pathogen surveillance and control.
Hector Moreno, Alberto Rastrojo, Rhys Pryce, Chiara Fedeli, Gert Zimmer, Thomas A Bowden, Gisa Gerold, Stefan Kunz   +7 more
doaj   +1 more source