Results 111 to 120 of about 2,741 (176)

Role of Hippo Pathway Effector Tafazzin Protein in Maintaining Stemness of Umbilical Cord-Derived Mesenchymal Stem Cells (UC-MSC) [Elektronisk resurs]

, 2018
Tafazzin (TAZ) protein has been upregulated in various types of human cancers, although the basis for elevation is uncertain, it has been made definite that the effect of mutation in the hippo pathway, particularly when it is switched off, considerably ...
Gopinath, Madhumala,, Marotta, Francesco,, Sun, Xiao-Feng,, Subramaniam, Vimala Devi,, Narasimhan, Srinivasan,, Priya K, Swarna,, Murugesan, Ramachandran,, Banerjee, Antara,, Sriramulu, Sushmitha,, Di Liddo, Rosa,, Jothimani, Ganesan,, Pathak, Surajit,   +11 more
core  

Stimulating the sir2–spargel axis rescues exercise capacity and mitochondrial respiration in a Drosophila model of Barth syndrome

Disease Models & Mechanisms, 2022
Deena Damschroder, Rubén Zapata-Pérez, Kristin Richardson, Frédéric M. Vaz, Riekelt H. Houtkooper, Robert Wessells   +5 more
doaj   +1 more source

Corrigendum: Re-expression of tafazzin isoforms in TAZ-deficient C6 glioma cells restores cardiolipin composition but not proliferation rate and alterations in gene expression

Frontiers in Genetics, 2022
Gayatri Jagirdar, Matthias Elsner, Christian Scharf, Stefan Simm, Katrin Borucki, Daniela Peter, Michael Lalk, Karen Methling, Michael Linnebacher, Mathias Krohn, Carmen Wolke, Uwe Lendeckel   +11 more
doaj   +1 more source

De novo synthesis of cardiolipin controls respiratory chain biogenesis in neonatal mouse hearts. [PDF]

EMBO Rep
Ren M, Xu Y, Phoon CKL, Erdjument-Bromage H, Neubert TA, Schlame M.   +5 more
europepmc   +1 more source

Cardiolipin as a Signaling Hub: Evolutionary Conservation and Programmable Platforms Coupling Mitochondrial Stress to Cell Fate. [PDF]

Int J Mol Sci
Petit PX.
europepmc   +1 more source

Cardiolipin remodelling in mitochondrial therapeutics: translational evidence chains from elamipretide to emerging strategies. [PDF]

Front Physiol
Di K, Hu Y, Sun H, Meng T, Han T, Qie R.
europepmc   +1 more source

The impact of Tafazzin deficiency on the functional and immunological characteristics of B lymphocytes

, 2022
Barth syndrome (BTHS) is a rare X-linked genetic disease classically characterized by cardiomyopathy, skeletal myopathy, and neutropenia. It is caused by mutations in the TAFAZZIN gene, which codes for the protein tafazzin (Taz), and this results in alterations in the level and molecular composition of the mitochondrial phospholipid cardiolipin with ...
openaire   +1 more source

The molecular mechanisms of crista formation: how mitochondria give themselves breathing room. [PDF]

Biochem Soc Trans
Colina-Tenorio L, Bohuslavová M, Bruce AW, Hashimi H.   +3 more
europepmc   +1 more source

Cross-species evidence for cardiolipin remodeling in neonatal hypoxic-ischemic encephalopathy. [PDF]

J Cereb Blood Flow Metab
Emaus KJ, Fogo GM, Raghunayakula S, Gruley E, McCracken L, Dubs C, Speas RL, Torres Torres FJ, Wider JM, Sanderson TH.   +9 more
europepmc   +1 more source

Metabolic cardiomyopathies: untangling clinical heterogeneity with human stem-cell derived models. [PDF]

EMBO Mol Med
Passadouro AS, Balfoort BM, Langeveld M, van Karnebeek CDM, van der Velden J, Houtkooper RH, Mosegaard S.   +6 more
europepmc   +1 more source