Results 121 to 130 of about 2,741 (176)

Lard Intake Reduced Tetralinoleoyl Cardiolipin and Attenuated the Cardioprotective Effects of Exercise in Mice With Pressure Overload-Induced Heart Failure. [PDF]

Circ Rep
Kitamura A, Ohminami H, Oshima A, Matsubara M, Sato T, Takikawa M, Ohnishi K, Masuda M, Yamanaka-Okumura H, Miura S, Taketani Y.   +10 more
europepmc   +1 more source

Understanding the role of MLCL AT-1 and tafazzin in mitochondrial function

, 2015
Cardiolipin (CL) is a phospholipid found exclusively in mitochondria and is required for normal mitochondrial function. CL biosynthesis requires a crucial remodelling step that incorporates specific acyl chains onto its molecular structure. The enzyme primarily responsible for CL remodelling is Tafazzin (TAZ), a mitochondrial protein encoded by the TAZ
openaire   +1 more source

Saturated cardiolipins are potent disruptors of inner mitochondrial membrane structure and function. [PDF]

J Biol Chem
Venkatraman K, Milshteyn D, Sarto C, Kocharian E, Sakurai CM, Armando AM, Wong AM, Dennis EA, Fang X, Lee CT, Budin I.   +10 more
europepmc   +1 more source

A mouse model of short-term, diet-induced fatty liver with abnormal cardiolipin remodeling via downregulated Tafazzin gene expression

Background Cardiolipin (CL) helps maintain mitochondrial structure and function. Here we investigated whether a high carbohydrate diet (HCD) fed to mice for a short period (5 days) could modulate the CL level, including that of monolysoCL (MLCL) in the ...
Chiba, Hitoshi, Yamahata, Arisa, Chen, Zhen, Sekiguchi, Hirotaka, Hayasaka, Takahiro, Hui, Shu-Ping, Sakurai, Toshihiro, Satoh, Hiroshi   +7 more
core  

Insights into Neutrophil Dysfunction in Inherited Metabolic Disorders. [PDF]

J Innate Immun
Wolf A, Montanelli G, Mathis D, Felser A, Laemmle A, Nuoffer JM, Gautschi M, Bourquin C, Stojkov D.   +8 more
europepmc   +1 more source

Running rich: how excess fatty acid oxidation drains the cardiac engine. [PDF]

J Clin Invest
Claypool SM, Koehler CM.
europepmc   +1 more source

Granulopoietic Dysregulation in a Patient-Tailored Mouse Model of Barth Syndrome. [PDF]

Stem Cell Rev Rep
Sierra Potchanant EA, Capitano ML, Edwards DM, Ramdas B, Cooper S, Ropa J, Pay SL, Sheth A, Snider PL, Vernon HJ, Tran NT, Kapur R, Conway SJ.   +12 more
europepmc   +1 more source

Disturbed mitochondrial maturation in cardiolipin remodeling-deficient cardiomyocytes. [PDF]

iScience
Senoo N, Sheridan MS, Wohlfarter Y, Primrose MT, Tampakakis E, Keller MA, Claypool SM.   +6 more
europepmc   +1 more source

De-succinylation-induced accumulation of TRMT10C in the nucleus plays a detrimental role in coronary microembolization via its m1A modification function. [PDF]

Int J Biol Sci
Hu CK, Huang WZ, He L, Chang C, Ren YL, Dai RX, Wu Q, Su Q.   +7 more
europepmc   +1 more source

Letter to the Editor: CRISPR-based gene editing for cardiac protection in Barth syndrome. [PDF]

Ann Med Surg (Lond)
Abedin ZU, Waggan AI, Khan E, Suleman MU, Tabassum SN.   +4 more
europepmc   +1 more source