Results 111 to 120 of about 7,425,562 (280)

Biomimetic Hybrid‐Membrane Nanoreactor for Deep‐Seated Photodynamic Immunotherapy of Hepatocellular Carcinoma via Dual Catalysis‐Enhanced ROS Amplification and cGAS‐STING Activation

Advanced Functional Materials, EarlyView.
UCNP@MnOx‐Hyp@HRM (UMHM) enables tumor targeting and accumulation. Under 808 nm NIR irradiation, PDT/CDT synergistically triggers ICD and cGAS–STING immunity for deep hepatocellular carcinoma therapy. ABSTRACT Photodynamic therapy (PDT) is promising against hepatocellular carcinoma (HCC).
Wen Li, Jianzhang Luo, Pei Lu, Dongqing Liu, Huijun Yi, Xiaoyuan Yi, Bixia Chi, Wen Chen, Qingyu Zeng, Feifei He, Liyan Wang   +10 more
wiley   +1 more source

Influence of thymic peptides preparation (t-activin) on anxiety level in rats

RUDN Journal of Medicine, 2012
Influence of T-activin on anxiety level in rats in the Porsolt test and the tail suspension test has been studied. Positive effect of thymic polypeptides resulted in the reduction of immobility and in the increase of escape-related activity.
A V Novoseletskaya, A N Inozemtsev, N M Kiseleva, V Ya Arion   +3 more
doaj  

The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice.

, 2005
Since its introduction almost 20 years ago, the tail suspension test has become one of the most widely used models for assessing antidepressant-like activity in mice.
Mombereau, Cedric, Vassout, Annick, Cryan, John F.   +2 more
core  

Altered baroreflex function after tail suspension in the conscious rat

, 1990
Experiments were performed on conscious chronically instrumented rats to determine the contribution of peripheral V2-vasopressinergic receptors in any alteration of baroreceptor reflex (BRR) sensitivity on release from 1 wk of 30 degrees head-down tilt ...
B. L. Brizzee, B. R. Walker
core   +1 more source

Spatially Controlled Embedded Bioprinting of Prevascularized Spheroids‐Containing Biopatch Enables Functional Skin Regeneration

Advanced Healthcare Materials, EarlyView.
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn, Gyu Tae Park, Dongjun Lee, Sik Yoon, Sae‐Ock Oh, Jae Ho Kim, Byoung Soo Kim   +6 more
wiley   +1 more source

Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

Advanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez, Dimple Chouhan, Kevin D. Browne, James Lim, Saarang P. Karandikar, Rodrigo A. España, John E. Duda, H. Isaac Chen, D. Kacy Cullen   +8 more
wiley   +1 more source

Evaluation of antidepressant-like effect of hydroalcoholic extract of Passiflora incarnata in animal models of depression in male mice [PDF]

Journal of HerbMed Pharmacology, 2014
Introduction: Passiflora incarnata (PI) is one of the commonest herbal anti-anxiety and sedative agents. The aim of the present study was to investigate the antidepressant effect of hydroalcoholic extract of PI in forced swim test (FST) and tail ...
Jafarpoor Nima, Abbasi-Maleki Saeid, Asadi-Samani Majid, Khayatnouri Mir Hadi   +3 more
doaj  

Macrophage–Fibroblast Crosstalk Governs Tumor Mechanics, as Revealed by Spatiotemporal Force Mapping in 3D Spheroids

Advanced Healthcare Materials, EarlyView.
This study shows crosstalk among tumor cells, fibroblasts, and macrophages alters the physical forces inside 3D tumor spheroids. Incorporating deformable microparticles in 3D tumor spheroids, the researchers mapped mechanical stresses spatially and with respect to tumor growth (temporally).
Kunal P. Pednekar, Daan Vorselen, Jai Prakash   +2 more
wiley   +1 more source

Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers

Advanced Healthcare Materials, EarlyView.
Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li, Chunbai Xiang, Ye Xu, Yu Liu, Keze Hong, Fanchu Zeng, Gelin Xu, Zhao‐Xi Wang, Jonathan L. Sessler, Ping Gong   +9 more
wiley   +1 more source

"Maximum Covariance Di erence Test for Equality of Two Covariance Matrices" [PDF]

We propose a test of equality of two covariance matrices based on the maximum standardized di erence of scalar covariances of two sample covariance matrices.We derive the tail probability of the asymptotic null distribution of the test statistic by the ...
Akimichi Takemura, Satoshi Kuriki
core