Results 31 to 40 of about 418,182 (306)

Mass spectrometry: an essential tool to be used in discrimination between causes of congenital adrenal hyperplasia, and its benefits versus radioimmunoassay

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2021
Background Measurement of multiple steroids, 17 hydroxyprogesterone, 11 deoxycortisol, and 21 deoxycortisol, is required to discriminate between congenital adrenal hyperplasia due to 21 hydroxylase deficiency and that due to 11 beta hydroxylase ...
Heba Asfour   +6 more
doaj   +1 more source

Two-dimensional mass spectrometry: new perspectives for tandem mass spectrometry [PDF]

open access: yesEuropean Biophysics Journal, 2019
Fourier transform ion cyclotron resonance mass analysers (FT-ICR MS) can offer the highest resolutions and mass accuracies in mass spectrometry. Mass spectra acquired in an FT-ICR MS can yield accurate elemental compositions of all compounds in a complex sample. Fragmentation caused by ion-neutral, ion-electron, or ion-photon interactions leads to more
Maria A. van Agthoven   +4 more
openaire   +4 more sources

Assessing Budding Yeast Phosphoproteome Dynamics in a Time-Resolved Manner using TMT10plex Mass Tag Labeling

open access: yesSTAR Protocols, 2020
Summary: Amine-reactive Tandem Mass Tag 10plex (TMT10plex) labeling permits multiplexed protein identification and quantitative analysis by tandem mass spectrometry (MS/MS).
Andrew W. Jones   +4 more
doaj   +1 more source

Rapid identification of E. coli bacteriophages using mass spectrometry [PDF]

open access: yes, 2017
Objective: The current increasing interest in the application of mass spectrometry, in particular MALDI-TOF MS, to identification of bacteria and fungi calls for a need to utilise this technology for identification of other infectious agents such as ...
Pantoja Munoz, Leonardo   +4 more
core   +1 more source

Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry for Simultaneous Determination of Antipsychotic Drugs in Human Plasma and Its Application in Therapeutic Drug Monitoring

open access: yesDrug Design, Development and Therapy, 2021
Yingjie Qi, Guangxuan Liu Department of Pharmacy, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang, 110042, Liaoning Province, People’s Republic of ChinaCorrespondence: Yingjie QiDepartment of Pharmacy,
Qi Y, Liu G
doaj  

Method development and validation of HPLC tandem/mass spectrometry for quantification of perindopril arginine and amlodipine besylate combination in bulk and pharmaceutical formulations

open access: yesResearch in Pharmaceutical Sciences, 2017
A well-characterized and fully validated ultra-high performance liquid chromatography-electrospray ionization-tandem mass spectrometric (UHPLC-ESI-MS/MS) method was developed to reliably analyze combination of perindopril arginine and amlodipine besylate
Kalaiyarasi Duraisamy   +2 more
doaj   +1 more source

Mucin glycosylation and sulphation in airway epithelial cells is not influenced by cystic fibrosis transmembrane conductance regulator expression [PDF]

open access: yes, 2005
Abnormalities in mucus properties and clearance make a major contribution to the pathology of cystic fibrosis (CF). Our aim was to test the hypothesis that the defects in CF mucus are a direct result of mutations in the CF transmembrane conductance ...
Dell, Anne   +6 more
core   +1 more source

Efficacy and outcome of expanded newborn screening for metabolic diseases - Report of 10 years from South-West Germany *

open access: yesOrphanet Journal of Rare Diseases, 2011
Background National newborn screening programmes based on tandem-mass spectrometry (MS/MS) and other newborn screening (NBS) technologies show a substantial variation in number and types of disorders included in the screening panel.
Mengel Eugen   +11 more
doaj   +1 more source

Analysis of urinary sphingolipids using liquid chromatography‐tandem mass spectrometry in diabetic nephropathy

open access: yesJournal of Diabetes Investigation, 2020
Aims/Introduction Sphingolipids, such as ceramides and sphingosine, are involved in the pathogenesis of diabetes; however, the modulation of urinary sphingolipids in diabetic nephropathy has not been fully elucidated.
Yoshifumi Morita   +7 more
doaj   +1 more source

MS²PIP: a tool for MS/MS peak intensity prediction [PDF]

open access: yes, 2013
Motivation: Tandem mass spectrometry provides the means tomatch mass spectrometry signal observations with the chemical entities that generated them. The technology produces signal spectra that contain information about the chemical dissociation pattern ...
Degroeve, Sven, Martens, Lennart
core   +2 more sources

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