Results 101 to 110 of about 183,884 (308)

Gold(I)-Catalyzed Tandem Intramolecular Methoxylation/Double Aldol Condensation Strategy Yielding 2,2′-Spirobi[indene] Derivatives

The syntheses of 2,2′-spirobi­[indene] derivatives based on a gold­(I)-catalyzed tandem strategy involving intramolecular methoxylation/double aldol condensation were achieved. Examination of the scope of this tandem reaction by using a batch of alkynone
Jingfu Zhang (13795049), Zhixing Ding (13795052), Yongxiang Liu (513367), Maosheng Cheng (1409932), Anbin Hou (11218840), Jiayue Fu (4100434), Sen Zhang (498066), Lu Yang (30847), Hongwei Su (6381158), Bin Lin (302181)   +9 more
core   +1 more source

Recycling Catalyst as Reactant: A Sustainable Strategy To Improve Atom Efficiency of Organocatalytic Tandem Reactions

, 2018
A sustainable strategy by internally recycling an organocatalyst as a reactant in a downstream reaction to improve the atom efficiency of organocatalytic tandem reactions is described.
Jun Wu (4002), Yuhai Tang (1819468), Yang Li (7082), Yan Zhou, Ge Deng (5818727), Ge Deng, Ziyu Liu (2566468), Wen Wei, Yuhai Tang, Ziyu Liu, Jun Wu, Yang Li, Yan Zhou (6523), Silong Xu, Junjie Zhang (355622), Junjie Zhang, Wen Wei (111015), Silong Xu (1819465)   +17 more
core   +1 more source

Artificial urinary sphincter revision for urethral atrophy: comparing single cuff downsizing and tandem cuff placement

International Brazilian Journal of Urology
Objective To compare outcomes for single urethral cuff downsizing versus tandem cuff placement during artificial urinary sphincter (AUS) revision for urethral atrophy. Materials and Methods We identified 1778 AUS surgeries performed at our institution
Brian J. Linder, Boyd R. Viers, Matthew J. Ziegelmann, Marcelino E. Rivera, Daniel S. Elliott   +4 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Effects of TANDEM Caregiver Training Strategy Compared to RECAPS/MESSAGE Training Strategy for Caregivers of Populations with Dementia

, 2014
Effects of TANDEM Caregiver Training Strategy Compared to RECAPS/MESSAGE Training Strategy for Caregivers of Populations with ...
Manning, Amber, Dinneen, Laina
core  

A Novel Strategy for Targeted Lipidomics Based on LC-Tandem-MS Parameters Prediction, Quantification, and Multiple Statistical Data Mining: Evaluation of Lysophosphatidylcholines as Potential Cancer Biomarkers

, 2019
Lipid quantification is the ultimate goal in lipidomics studies challenged by the availability of standard compounds. A novel strategy for targeted lipidomics based on LC-MS/MS parameters prediction and multivariate statistical analysis was developed for
Peng Gao, Ran Liu (303585), Wei Jin, Xiao Yang (19898), Qing Li (84975), Yiwen Zhang (512835), Yiwen Zhang, Huarong Xu (424596), Qing Li, Kaishun Bi, Kaishun Bi (429547), Peng Gao (35465), Ran Liu, Xiao Yang, Qian Zhang, Wei Jin (87150), Huarong Xu, Qian Zhang (49333)   +17 more
core   +1 more source

Bispecific CAR-T cells targeting CD19/20 in patients with relapsed or refractory B cell non-Hodgkin lymphoma: a phase I/II trial

Blood Cancer Journal
Non-Hodgkin lymphoma (NHL) is a common malignancy in the hematologic system, and traditional therapy has limited efficacy for people with recurrent/refractory NHL (R/R NHL), especially for patients with diffuse large B cell lymphoma (DLBCL).
Lixin Wang, Chuling Fang, Qingzheng Kang, Wenfa Huang, Ziren Chen, Weiqiang Zhao, Lei Wang, Yiran Wang, Kun Tan, Xiao Guo, Yuanyuan Xu, Shuhong Wang, Lijun Wang, Jingqiao Qiao, Zhixiong Tang, Chuan Yu, Yang Xu, Yisheng Li, Li Yu   +18 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source