Results 91 to 100 of about 183,884 (308)

Synthesis of indoles via a tandem benzannulation-cyclization strategy [PDF]

, 2008
Vita.Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2008.Includes bibliographical references.Vinylketenes (generated in situ from cyclobutenones or a-diazo ketones) react with ynamides via a pericyclic cascade process to ...
Lam, Tin Yiu
core  

Double promoter and tandem gene strategy for efficiently expressing recombinant FGF21

Microbial Cell Factories
Background Fibroblast growth factor 21 (FGF21) is a promising candidate for treating metabolic disorder diseases and has been used in phase II clinical trials.
Longying Liu, Nuoyi Ning, Simeng Xu, Dongqing Chen, Luping Zhou, Zhimou Guo, Xinmiao Liang, Xianlong Ye   +7 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Spaceborne Autonomous and Ground Based Relative Orbit Control for the TerraSAR-X/TanDEM-X Formation

, 2007
TerraSAR-X (TSX) and TanDEM-X (TDX) are two advanced synthetic aperture radar (SAR) satellites flying in formation. SAR interferometry allows a high resolution imaging of the Earth by processing SAR images obtained from two slightly different orbits. TSX
Gill, Eberhard, Ardaens, J. S., Kazeminejad, Bobby, Montenbruck, O., Ardaens, Jean-Sebastien, D'Amico, Simone, Montenbruck, Oliver, D'Amico, S., Gill, E., Kazeminejad, B.   +9 more
core  

Tuning the wettability of tandem electrodes affects CO2 electro-conversion to multicarbon products

Applied Surface Science Advances
The tandem catalyst configuration has emerged as an effective strategy for enhancing the electrochemical conversion of CO2 into multicarbon (C2+) products by incorporating a CO-producing layer with a Cu catalyst. While numerous catalyst combinations have
Subin Park, Hyunwook Kim, Dongjin Kim, Younghyun Chae, Se-Woong Baek, Dong Ki Lee, Ung Lee, Da Hye Won   +7 more
doaj   +1 more source

Computational and experimental demonstrations of one-pot tandem catalysis for electrochemical carbon dioxide reduction to methane

Nature Communications, 2019
Carbon dioxide can be electrocatalytically reduced to valuable fuels and chemicals, but is hindered by poor catalytic efficiency and selectivity. Here the authors report improved electrocatalytic conversion of carbon dioxide into methane using a tandem ...
Haochen Zhang, Xiaoxia Chang, Jingguang G. Chen, William A. Goddard, Bingjun Xu, Mu-Jeng Cheng, Qi Lu   +6 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

TanDEM-X Acquisition Planner

, 2012
The TanDEM-X mission (TerraSAR-X add-on for Digital Elevation Measurement) consists of two almost iden-tical satellites, TerraSAR-X (TSX) and TanDEM-X (TDX), launched in 2006 and 2010 respectively.
Schulze, Daniel, Ortega-Miguez, Carlos, Rizzoli, Paola, Polimeni, Maria Donata, Bachmann, Markus, Böer, Johannes   +5 more
core  

Device simulation and experimental validation of perovskite-cadmium telluride 4T tandem solar cell

Frontiers in Energy Research
Developing tandem solar cells is an excellent strategy to break through the Shockley–Queisser (SQ) limit for single-junction solar cells. A major factor in developing a tandem solar cell is to make it cost-efficient with high device performance. Here, we
Harigovind Menon, Feng Yan
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source