Results 11 to 20 of about 11,164 (212)

The Jasmonate-Responsive SmMPK3-SmWRKY33 Module Positively Regulates Tanshinone Biosynthesis in Salvia miltiorrhiza. [PDF]

Plant Biotechnol J
ABSTRACT Tanshinones, the major bioactive diterpenes in Salvia miltiorrhiza Bunge, are widely used to treat cardiovascular and cerebrovascular diseases. While jasmonates (JAs) are known to modulate tanshinones accumulation, the molecular link between JA signalling and tanshinone biosynthesis remains unclear.
Qu R, Wang S, Wang X, Peng J, Guo J, Cui G, Chen T, Chen M, Zhao S, Shen Y.   +9 more
europepmc   +2 more sources

Salvia columbariae contains tanshinones [PDF]

Evidence-Based Complementary and Alternative Medicine, 2005
Salvia columbariae (chia) was examined and found to contain miltionone II, cryptotanshinone and tanshinone IIA. These compounds may be of interest in the treatment of stroke and heart attack.
Adams, James D., Wall, Michael, Garcia, Cecilia   +2 more
openaire   +2 more sources

Total Syntheses of Tanshinone-I, Tanshinone-II and Cryptotanshinone [PDF]

Bulletin of the Chemical Society of Japan, 1968
Abstract Total syntheses of tanshinone-II (II) and cryptotanshinone (III) from 3-methylbenzofuran-4, 7-quinone (X) and 6,6-dimethyl-l-vinylcyclohexene (IX), and of tanshinone-I (I) from quinone X and o-methylstyrene (XVIII) are described. Preliminary accounts for the Diels-Alder reaction of methoxybenzoquinone revealed that the effect of
Hiroshi Kakisawa, Yoshinobu Inouye
openaire   +1 more source

The Skeletal Effects of Tanshinones: A Review [PDF]

Molecules, 2021
Background: Osteoporosis results from excessive bone resorption and reduced bone formation, triggered by sex hormone deficiency, oxidative stress and inflammation. Tanshinones are a class of lipophilic phenanthrene compounds found in the roots of Salvia miltiorrhiza with antioxidant and anti-inflammatory activities, which contribute to its anti ...
Sophia Ogechi Ekeuku, Kok-Lun Pang, Kok-Yong Chin   +2 more
openaire   +3 more sources

Tanshinone IIA Stimulates Erythrocyte Phosphatidylserine Exposure [PDF]

Cellular Physiology and Biochemistry, 2012
Tanshinone IIA, an antimicrobial, antioxidant, antianaphylactic, antifibrotic, vasodilating, antiatherosclerotic, organo-protective and antineoplastic component from the rhizome of Salvia miltiorrhiza, is known to trigger apoptosis of tumor cells. Tanshinone IIA is effective in part through mitochondrial depolarization and altered gene expression ...
ZELENAK C., PASHAM V., JILANI K., TRIPODI P.M., ROSACLERIO L., PATHARE G., LUPESCU A., FAGGIO, Caterina, QADRI S.M., LANG F.   +9 more
openaire   +5 more sources

Tanshinone IIA changed the amniotic fluid volume and regulated expression of AQP1 and AQP3 in amniotic epithelium cells: a promising drug treating abnormal amniotic fluid volume

Molecular Medicine, 2023
Background Many studies have confirmed the association of aquaporins (AQPs) with abnormal amniotic fluid volume (AFV). In our previous experiments, we found that Tanshinone IIA was able to regulate the expression of AQP1 and AQP3.
Shuangjia Pan, Yehui Lan, Baoyi Chen, Yujia Zhou, Xinxin Ying, Ying Hua   +5 more
doaj   +1 more source

Tanshinone I and Tanshinone IIA/B attenuate LPS-induced mastitis via regulating the NF-κB

Biomedicine & Pharmacotherapy, 2021
Mastitis is a common disease occurs in breast-feeding mothers, but published data are poor. This study aimed to study the effects of Tanshinones on treating mastitis.Clinical trials performed in 58 breast-feeding mothers were carried out. B-ultrasound and blood test were used to measure the size of breast mass and the change of blood cell counts.
Lili, Yang, Guanglin, Zhou, Jinghua, Liu, Jinshuang, Song, Zongyu, Zhang, Qi, Huang, Fengxiang, Wei   +6 more
openaire   +2 more sources

Counter-current chromatography for the separation of terpenoids: A comprehensive review with respect to the solvent systems employed [PDF]

, 2014
Copyright @ 2014 The Authors.This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.Natural ...
A Berthod, A Berthod, A Koch, A Li, A Marston, A Maurya, A Peng, A Sun, ALM Nasser, AM Martin, AS Engelberth, AS Graham, B Diallo, B Diallo, B Medhi, B Pinel, BCB dos Santos, BK Gosse, C Zhao, CR Cheng, D Agostinho, D Du, D Fisher, D Grancher, D Wang, D Wang, D Wu, D Zhao, E Mudge, F Chen, F Chen, F Chen, F Fullas, F Gutiérrez, F He, F Oka, F Qiu, F Xiang, F Yang, G Tian, G Tian, G Wang, G Yan, GD Brown, GG Rocha, H Knapp, H Wu, H Ye, H Ye, H Zhang, HB Li, HB Li, HB Li, HB Li, HT Lu, I Slacanin, IA Sutherland, IA Sutherland, IA Sutherland, Ian Garrard, IJ Garrard, IJ Garrard, IJ Garrard, IJ Ha, J Hu, J Huang, J Liang, J Liu, J Ma, J Peng, J Wang, J Wang, J Wang, J Xie, J Xie, J Xu, J Yan, JCT Silva, JH Lee, JP Fan, JT Fischedick, JT Fischedick, JT Fischedick, K Skalicka-Woźniak, KD Yoon, KD Yoon, Krystyna Skalicka-Woźniak, KY Yoo, M Gu, M Gu, M Hamzaoui, M Lechtenberg, M Liu, M Puertas Mejia, MP Gasper, N Acton, N Fischer, N Frighetto, O Shehzad, O Shehzad, O Shehzad, O Shirota, O Shirota, P Hewitson, PA Souza De, PK Ajikumar, Q Chen, Q Du, Q Du, Q Du, Q Du, Q Du, Q Du, Q Du, QB Han, QB Han, QB Han, R Aman, R Graziose, R Roscher, R Tsao, RTS Frighetto, S Baldermann, S Baldermann, S He, S Liu, S Shi, S Wu, S Wu, S Yao, S Yao, SM Kim, SS Cicek, SY Shi, T Abbott, VF Rodrigues, VGP Severino, VP da Silva, W He, X Cao, X Han, X Qi, X Shi, X Xiao, X Xin, XC Li, XH Xiao, XY Huang, Y Cheng, Y Cheng, Y Geng, Y Ikai, Y Ito, Y Ito, Y Ito, Y Ito, Y Jiang, Y Lu, Y Lu, Y Ma, Y Wang, Y Wei, Y Wei, Y Wei, Y Yang, Y Yang, Y Yuan, Y Zhang, Y Zhao, YW Ha, YW Ha, YY Dang, Z Jiang   +172 more
core   +2 more sources

A Skin Lipidomics Study Reveals the Therapeutic Effects of Tanshinones in a Rat Model of Acne

Frontiers in Pharmacology, 2021
Tanshinone (TAN), a class of bioactive components in traditional Chinese medicinal plant Salvia miltiorrhiza, has antibacterial and anti-inflammatory effects, can enhance blood circulation, remove blood stasis, and promote wound healing.
Tingting Chen, Zhaoming Zhu, Qunqun Du, Zhuxian Wang, Wenfeng Wu, Yaqi Xue, Yuan Wang, Yufan Wu, Quanfu Zeng, Cuiping Jiang, Chunyan Shen, Li Liu, Hongxia Zhu, Qiang Liu   +13 more
doaj   +1 more source

Combining Metabolomics and Transcriptomics to Characterize Tanshinone Biosynthesis in Salvia Miltiorrhiza [PDF]

, 2014
Plant natural products have been co-opted for millennia by humans for various uses such as flavor, fragrances, and medicines. These compounds often are only produced in relatively low amounts and are difficult to chemically synthesize, limiting access ...
Cui, Guanghong, Gao, Wei, Hillwig, Matthew L, Huang, Luqi, Jackson, Alana, Peters, Reuben J, Shen, Ye, Sun, Hai-Xi, Wang, Xiao, Wang, Xiu-Jie, Xiao, Hongbin, Zhang, Liangxiao, Zhao, Nan   +12 more
core   +3 more sources