Results 51 to 60 of about 5,178 (152)

Viral Pathogens and Pulmonary Fibrosis: EMT‐Driven Mechanisms and Insights From Traditional Chinese Medicine

Reviews in Medical Virology, Volume 36, Issue 2, March 2026.
ABSTRACT Idiopathic pulmonary fibrosis (IPF) is a serious progressive complication of the respiratory system, which is profoundly associated with persistent extracellular matrix (ECM) deposition, fibrosis, and disrupted tissue regeneration. Emerging evidence shows that epithelial–mesenchymal transition (EMT) acts as a key factor in the pathogenesis of ...
Ningzi Zang, Yingxu Wu, Pin Li, Yongming Liu, Shiwen Wang, Jiapeng Leng, Libin Zhan, Xiaodong Lyu, Lijian Pang, Jiaran Wang   +9 more
wiley   +1 more source

Response of Endophytic Microbial Communities and Quality of Salvia miltiorrhiza to Fertilization Treatments

Microorganisms
Salvia miltiorrhiza is a traditional herbal remedy for cardiovascular diseases and is in high demand in the market. Excessive chemical fertilizer application, resulting from unscientific fertilization practices, reduced the tanshinone content in S ...
Wenjing Chen, Wanyun Li, Yangyang Pan, Xin Zheng, Xinxin Fu, Menghui Wang, Wenyi Shi, Zhenzhou Wang, Xueli He, Chao He, Xianen Li   +10 more
doaj   +1 more source

The Expression Profiles of the Salvia miltiorrhiza 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase 4 Gene and Its Influence on the Biosynthesis of Tanshinones

Molecules, 2022
Salvia miltiorrhiza is a medicinal plant that synthesises biologically-active tanshinones with numerous therapeutic properties. An important rate-limiting enzyme in the biosynthesis of their precursors is 3-hydroxy-3-methylglutaryl-coenzyme A reductase ...
Małgorzata Majewska, Piotr Szymczyk, Jan Gomulski, Agnieszka Jeleń, Renata Grąbkowska, Ewa Balcerczak, Łukasz Kuźma   +6 more
doaj   +1 more source

Effects of environmental factors on genetic diversity in the endangered Notopterygium incisum from the southeastern Qinghai–Tibetan Plateau

Plant Species Biology, Volume 41, Issue 2, March 2026.
This study focuses on 38 populations of Notopterygium incisum from its main distribution areas (Sichuan Province, Gansu Province, and Qinghai Province), conducting molecular genetic diversity analysis and investigating the correlations between genetic variation and climatic variables, geographical distribution, and elevation gradients.
Jinqiu Liao, Ao Luo, Rui Zeng, Xianhong Feng, Yuanyuan Jiang, Xuexue Deng, Li Zhang, Ruiwu Yang   +7 more
wiley   +1 more source

Enhanced production of tanshinone IIA in endophytic fungi Emericella foeniculicola by genome shuffling

Pharmaceutical Biology, 2018
Context: Tanshinone IIA, commercially produced from Salvia miltiorrhiza Bunge (C.Y.Wu) (Labiatae), has various biological benefits. Currently, this compound is mainly extracted from plants.
Pengyu Zhang, Yiting Lee, Xiying Wei, Jinlan Wu, Qingmei Liu, Shanning Wan   +5 more
doaj   +1 more source

The Nrf2-inducers tanshinone I and dihydrotanshinone protect human skin cells and reconstructed human skin against solar simulated UV

Redox Biology, 2013
Exposure to solar ultraviolet (UV) radiation is a causative factor in skin photocarcinogenesis and photoaging, and an urgent need exists for improved strategies for skin photoprotection.
Shasha Tao, Rebecca Justiniano, Donna D. Zhang, Georg T. Wondrak   +3 more
doaj   +1 more source

Glycolysis enzymes and cellular lactylation in tumour

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
Graphical Headlights • Glycolytic enzymes regulate lactylation in cancer cells. • Lactylation drives tumour growth, metastasis, immune evasion and contributes to microenvironment remodelling. • Targeting lactylation holds promise for cancer therapy. Abstract Cellular lactylation, a recently identified post‐translational modification, has emerged as a ...
Chenyuan Dai, Lihua Wang
wiley   +1 more source

Tanshinone Content Prediction and Geographical Origin Classification of Salvia miltiorrhiza by Combining Hyperspectral Imaging with Chemometrics

Foods
Hyperspectral imaging (HSI) technology was combined with chemometrics to achieve rapid determination of tanshinone contents in Salvia miltiorrhiza, as well as the rapid identification of its origins.
Yaoyao Dai, Binbin Yan, Feng Xiong, Ruibin Bai, Siman Wang, Lanping Guo, Jian Yang   +6 more
doaj   +1 more source

Plant Growth and the Contents of Major Bioactive Compounds of Salvia miltiorrhiza Bunge Grown in Mississippi, United States

Horticulturae, 2023
Salvia miltiorrhiza Bunge (danshen) is a traditional herbal medicine and has been widely used to prevent and treat cardiovascular and other diseases. Currently, the majority of medicinal plants, including danshen, used in the United States are imported ...
Zhiheng Xing, Guihong Bi, Tongyin Li, Qianwen Zhang, Patricia R. Knight   +4 more
doaj   +1 more source

Ginsenoside Rg1 as a Multifunctional Therapeutic Agent: Pharmacological Properties, Molecular Mechanisms and Clinical Perspectives in Complementary Medicine

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Ginsenoside Rg1 (Rg1) from Panax ginseng shows multifunctional health effects. Although oral bioavailability is low and blood–brain barrier (BBB) penetration is limited, delivery systems such as liposomes and nanoparticles may improve exposure. Rg1 reduces inflammation/oxidative stress by inhibiting nuclear factor‐κB (NF‐κB) signaling and reactive ...
Hernán Cortés, Enrique Lima, Lorena Duarte‐Peña, Sheila I. Peña‐Corona, Zainab M. Almarhoon, Rajesh Kaverikana, Shivaprasad Shetty Mangalpady, Vinayaka Babu Shet, Nikshitha Manjeshwar, Javad Sharifi‐Rad, Jen‐Tsung Chen, Gerardo Leyva‐Gómez, William N. Setzer, Daniela Calina   +13 more
wiley   +1 more source