Endophyte Chaetomium globosum D38 Promotes Bioactive Constituents Accumulation and Root Production in Salvia miltiorrhiza [PDF]
Frontiers in Microbiology, 2018 Salvia miltiorrhiza is known for tanshinones and salvianolic acids, which have been shown to have a protective effect against ROS, especially for cardiovascular diseases and other various ailments of human organs.
Xin Zhai +9 more
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The effect of tanshinones on cognitive impairments in animal models of Alzheimer’s disease: a systematic review and meta-analysis [PDF]
Frontiers in PharmacologyBackgroundAlzheimer’s disease (AD) is an age-related neurological illness that poses a significant hazard to human health. A fat-soluble compound called tanshinones was isolated from Danshen, a traditional Chinese herb.
Shuwei Wang +7 more
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The Skeletal Effects of Tanshinones: A Review [PDF]
Molecules, 2021 Background: Osteoporosis results from excessive bone resorption and reduced bone formation, triggered by sex hormone deficiency, oxidative stress and inflammation.
Sophia Ogechi Ekeuku +2 more
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Therapeutic Potential of Tanshinones in Osteolytic Diseases: From Molecular and Cellular Pathways to Preclinical Models [PDF]
Dentistry JournalTanshinones are a class of lipophilic diterpenoid quinones extracted from Salvia miltiorrhiza (Dan shen), a widely used herb in traditional Chinese medicine. These compounds, particularly tanshinone IIA (T-IIA) and sodium tanshinone sulfonate (STS), have
Rafael Scaf de Molon
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Evaluation of the anti-inflammatory effects of synthesised tanshinone I and isotanshinone I analogues in zebrafish. [PDF]
PLoS ONE, 2020 During inflammation, dysregulated neutrophil behaviour can play a major role in a range of chronic inflammatory diseases, for many of which current treatments are generally ineffective.
Matthew J Foulkes +4 more
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SmEIL1 transcription factor inhibits tanshinone accumulation in response to ethylene signaling in Salvia miltiorrhiza [PDF]
Frontiers in Plant ScienceAmong the bioactive compounds, lipid-soluble tanshinone is present in Salvia miltiorrhiza, a medicinal plant species. While it is known that ethephon has the ability to inhibit the tanshinones biosynthesis in the S.
Xiujuan Li +7 more
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Cytotoxic diterpenoids from Salvia glutinosa and comparison with the tanshinone profile of danshen (Salvia miltiorrhiza). [PDF]
Front Plant Sci, 2023 The roots of Salvia miltiorrhiza are the source of the traditional Chinese medicine danshen and the class of tanshinones, particular quinoid nor-diterpenoids of the abietane type.
Ayvazyan A +4 more
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Comparative transcriptomic analysis and genome-wide identification provide insights into the potential role of fungal-responsive MAPK cascade genes in tanshinone accumulation in Salvia miltiorrohiza [PDF]
Frontiers in Plant ScienceSalvia miltiorrhiza is a well-known traditional Chinese medicine (TCM) for its bioactive tanshinones that are used to treat various diseases and have high antimicrobial properties.
Ann Abozeid +10 more
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Research Progress on Regulation of Immune Response by Tanshinones and Salvianolic Acids of Danshen (Salvia miltiorrhiza Bunge) [PDF]
MoleculesAs one of the traditional Chinese herbs, Danshen (Salvia miltiorrhiza Bunge) has been widely studied and widely used in the treatment of cardiovascular, cerebrovascular, and other immune diseases.
Jiawen Tang, Xueying Zhao
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Comparative transcriptome analyses of different Salvia miltiorrhiza varieties during the accumulation of tanshinones [PDF]
PeerJ, 2021 Salvia miltiorrhiza (Labiatae) is an important medicinal plant in traditional Chinese medicine. Tanshinones are one of the main active components of S. miltiorrhiza. It has been found that the intraspecific variation of S.
Jingwen Zhou +4 more
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