The Skeletal Effects of Tanshinones: A Review [PDF]
Molecules, 2021 Background: Osteoporosis results from excessive bone resorption and reduced bone formation, triggered by sex hormone deficiency, oxidative stress and inflammation.
Sophia Ogechi Ekeuku +2 more
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Comparative transcriptomic analysis and genome-wide identification provide insights into the potential role of fungal-responsive MAPK cascade genes in tanshinone accumulation in Salvia miltiorrohiza [PDF]
Frontiers in Plant ScienceSalvia miltiorrhiza is a well-known traditional Chinese medicine (TCM) for its bioactive tanshinones that are used to treat various diseases and have high antimicrobial properties.
Ann Abozeid +10 more
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Research Progress on Regulation of Immune Response by Tanshinones and Salvianolic Acids of Danshen (Salvia miltiorrhiza Bunge) [PDF]
MoleculesAs one of the traditional Chinese herbs, Danshen (Salvia miltiorrhiza Bunge) has been widely studied and widely used in the treatment of cardiovascular, cerebrovascular, and other immune diseases.
Jiawen Tang, Xueying Zhao
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Comparative transcriptome analyses of different Salvia miltiorrhiza varieties during the accumulation of tanshinones [PDF]
PeerJ, 2021 Salvia miltiorrhiza (Labiatae) is an important medicinal plant in traditional Chinese medicine. Tanshinones are one of the main active components of S. miltiorrhiza. It has been found that the intraspecific variation of S.
Jingwen Zhou +4 more
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Proteins and DNA Sequences Interacting with Tanshinones and Tanshinone Derivatives. [PDF]
Int J Mol SciTanshinones, biologically active diterpene compounds derived from Salvia miltiorrhiza, interact with specific proteins and DNA sequences, influencing signaling pathways in animals and humans. This study highlights tanshinone–protein interactions observed at concentrations achievable in vivo, ensuring greater physiological relevance compared to in vitro
Szymczyk P, Majewska M, Nowak J.
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Evidence-Based Complementary and Alternative Medicine, 2005 Salvia columbariae (chia) was examined and found to contain miltionone II, cryptotanshinone and tanshinone IIA. These compounds may be of interest in the treatment of stroke and heart attack.
James D. Adams +2 more
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Total Syntheses of Tanshinone-I, Tanshinone-II and Cryptotanshinone [PDF]
Bulletin of the Chemical Society of Japan, 1968 Abstract Total syntheses of tanshinone-II (II) and cryptotanshinone (III) from 3-methylbenzofuran-4, 7-quinone (X) and 6,6-dimethyl-l-vinylcyclohexene (IX), and of tanshinone-I (I) from quinone X and o-methylstyrene (XVIII) are described. Preliminary accounts for the Diels-Alder reaction of methoxybenzoquinone revealed that the effect of
Hiroshi Kakisawa, Yoshinobu Inouye
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Metabolic profiles and cDNA-AFLP analysis of Salvia miltiorrhiza and Salvia castanea Diel f. tomentosa Stib. [PDF]
PLoS ONE, 2012 Plants of the genus Salvia produce various types of phenolic compounds and tanshinones which are effective for treatment of coronary heart disease. Salvia miltiorrhiza and S. castanea Diels f. tomentosa Stib are two important members of the genus.
Dongfeng Yang +7 more
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Therapeutic and pharmacological potential of Tanshinones against lung cancer: A systematic review
Phytomedicine Plus, 2022 Background: Lung cancer is the most prevalent of all cancers, causing the highest number of cancer-related deaths in men and the second-highest number in women worldwide.
Syed Sahajada Mahafujul Alam +4 more
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Tanshinone IIA Stimulates Erythrocyte Phosphatidylserine Exposure [PDF]
Cellular Physiology and Biochemistry, 2012 Tanshinone IIA, an antimicrobial, antioxidant, antianaphylactic, antifibrotic, vasodilating, antiatherosclerotic, organo-protective and antineoplastic component from the rhizome of Salvia miltiorrhiza, is known to trigger apoptosis of tumor cells. Tanshinone IIA is effective in part through mitochondrial depolarization and altered gene expression ...
ZELENAK C. +9 more
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