Results 11 to 20 of about 2,182 (156)

Comparative transcriptome analyses of different Salvia miltiorrhiza varieties during the accumulation of tanshinones [PDF]

PeerJ, 2021
Salvia miltiorrhiza (Labiatae) is an important medicinal plant in traditional Chinese medicine. Tanshinones are one of the main active components of S. miltiorrhiza. It has been found that the intraspecific variation of S.
Jingwen Zhou, Rui Liu, Min Shuai, Zhu-Yun Yan, Xin Chen   +4 more
doaj   +3 more sources

Molecular Mechanisms of Cardioprotective Actions of Tanshinones [PDF]

Journal of Chemistry, 2016
Tanshinones are lipophilic compounds derived from Salvia miltiorrhiza (Danshen) that has been widely used to treat coronary heart diseases in China. The cardioprotective actions of tanshinones have been extensively studied in various models of myocardial
Hyou-Ju Jin, Chun-Guang Li
doaj   +4 more sources

SmGRAS1 and SmGRAS2 Regulate the Biosynthesis of Tanshinones and Phenolic Acids in Salvia miltiorrhiza

Frontiers in Plant Science, 2019
Salvia miltiorrhiza is one of the most widely used traditional Chinese medicinal plants because of its excellent performance in treating heart diseases.
Wenrui Li, Wenrui Li, Zhenqing Bai, Tianlin Pei, Dongfeng Yang, Renjun Mao, Bingxue Zhang, Bingxue Zhang, Chuangfeng Liu, Zongsuo Liang, Zongsuo Liang   +10 more
doaj   +2 more sources

Deep sequencing identifies tissue-specific microRNAs and their target genes involving in the biosynthesis of tanshinones in Salvia miltiorrhiza. [PDF]

PLoS ONE, 2014
Salvia miltiorrhiza is one of the most popular traditional medicinal herbs in Asian nations. Its dried root contains a number of tanshinones, protocatechuic aldehyde, salvianolic acid B and rosmarinic, and is used for the treatment of various diseases ...
Xiangbin Xu, Qinghua Jiang, Xiuyan Ma, Qicai Ying, Bo Shen, Yongsheng Qian, Hongmiao Song, Huizhong Wang   +7 more
doaj   +2 more sources

Bioavailability and pharmacokinetic comparison of tanshinones between two formulations of Salvia miltiorrhiza in healthy volunteers

Scientific Reports, 2017
Salvia miltiorrhiza (SM) is widely used to treat microcirculatory disturbance-related diseases; its lipophilic components play important roles in this application.
Lu Xing, Zhi-Rong Tan, Jin-Le Cheng, Wei-Hua Huang, Wei Zhang, Wen Deng, Chun-Su Yuan, Hong-Hao Zhou   +7 more
doaj   +2 more sources

Diterpenoid Tanshinones and Phenolic Acids from Cultured Hairy Roots of Salvia miltiorrhiza Bunge and Their Antimicrobial Activities

Molecules, 2011
Four diterpenoid tanshinones and three phenolic acids were isolated from the crude ethanol extract of the cultured hairy roots of Salvia miltiorrhiza Bunge by bioassay-guided fractionation.
Peiqin Li, Jianyong Wu, Yan Mou, Jingfeng Lou, Jianglin Zhao, Ligang Zhou   +5 more
doaj   +2 more sources

Recent insights into the biological activities and drug delivery systems of tanshinones

International Journal of Nanomedicine, 2016
Yuee Cai,1,* Wenji Zhang,2,* Zirong Chen,3 Zhi Shi,1,2 Chengwei He,1 Meiwan Chen1 1State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, People’s Republic of China ...
Cai Y, Zhang W, Chen Z, Shi Z, He C, Chen M   +5 more
doaj   +1 more source

Growth Inhibition of Tanshinones on SPC-A-1 Cell Line and their Structure-activity Relationship

Chinese Journal of Lung Cancer, 2011
Background and objective Numerous studies have shown that Tanshinones have anti-tumor effects in vitro, but few studies were focusing on the anti-tumor activity of Tanshinones against one special cancer cell line.
Huayue SHI, Qing ZHANG, Hui LI, Ting CHU, Hui JIN, Shengjun MAO   +5 more
doaj   +1 more source

Ag+ as a More Effective Elicitor for Production of Tanshinones than Phenolic Acids in Salvia miltiorrhiza Hairy Roots

Molecules, 2014
Phenolic acids and tanshinones are two groups of bioactive ingredients in Salvia miltiorrhiza Bunge. As a heavy metal elicitor, it has been reported that Ag+ can induce accumulations of both phenolic acids and tanshinones in S. miltiorrhiza hairy roots.
Bingcong Xing, Dongfeng Yang, Wanli Guo, Zongsuo Liang, Xijun Yan, Yonghong Zhu, Yan Liu   +6 more
doaj   +2 more sources

Proteins and DNA Sequences Interacting with Tanshinones and Tanshinone Derivatives. [PDF]

Int J Mol Sci
Tanshinones, biologically active diterpene compounds derived from Salvia miltiorrhiza, interact with specific proteins and DNA sequences, influencing signaling pathways in animals and humans.
Szymczyk P, Majewska M, Nowak J.
europepmc   +2 more sources