Results 11 to 20 of about 2,942 (199)
Asian Journal of Pharmaceutical Sciences, 2017 Total tanshinones are lipophilic active constituents extracted from Salvia miltiorrhiza Bge. Tanshinone IIA and cryptotanshinone are the major components in total tanshinones.
Xifeng Zhai +4 more
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Tanshinones, Critical Pharmacological Components in Salvia miltiorrhiza [PDF]
Frontiers in Pharmacology, 2019 Salvia miltiorrhiza Bunge, a member of the Lamiaceae family, is valued in traditional Chinese Medicine. Its dried root (named Danshen) has been used for hundreds of years, primarily for the treatment of cardiovascular and cerebrovascular diseases ...
Zhouqian Jiang +4 more
doaj +3 more sources
Evidence-Based Complementary and Alternative Medicine, 2005 Salvia columbariae (chia) was examined and found to contain miltionone II, cryptotanshinone and tanshinone IIA. These compounds may be of interest in the treatment of stroke and heart attack.
James D. Adams +2 more
core +3 more sources
Proteins and DNA Sequences Interacting with Tanshinones and Tanshinone Derivatives. [PDF]
Int J Mol SciTanshinones, biologically active diterpene compounds derived from Salvia miltiorrhiza, interact with specific proteins and DNA sequences, influencing signaling pathways in animals and humans. This study highlights tanshinone–protein interactions observed at concentrations achievable in vivo, ensuring greater physiological relevance compared to in vitro
Szymczyk P, Majewska M, Nowak J.
europepmc +3 more sources
The Jasmonate-Responsive SmMPK3-SmWRKY33 Module Positively Regulates Tanshinone Biosynthesis in Salvia miltiorrhiza. [PDF]
Plant Biotechnol JABSTRACT Tanshinones, the major bioactive diterpenes in Salvia miltiorrhiza Bunge, are widely used to treat cardiovascular and cerebrovascular diseases. While jasmonates (JAs) are known to modulate tanshinones accumulation, the molecular link between JA signalling and tanshinone biosynthesis remains unclear.
Qu R +9 more
europepmc +2 more sources
Total Syntheses of Tanshinone-I, Tanshinone-II and Cryptotanshinone [PDF]
Bulletin of the Chemical Society of Japan, 1968 Abstract Total syntheses of tanshinone-II (II) and cryptotanshinone (III) from 3-methylbenzofuran-4, 7-quinone (X) and 6,6-dimethyl-l-vinylcyclohexene (IX), and of tanshinone-I (I) from quinone X and o-methylstyrene (XVIII) are described. Preliminary accounts for the Diels-Alder reaction of methoxybenzoquinone revealed that the effect of
Hiroshi Kakisawa, Yoshinobu Inouye
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Tanshinone I, tanshinone IIA, and cryptotanshinone: key bioactive components modulating vascular smooth muscle cell function. [PDF]
Front PharmacolCardiovascular diseases (CVDs) remain the leading cause of mortality among non-communicable diseases worldwide. Vascular smooth muscle cells (VSMCs), as the predominant cellular component of the tunica media, are essential for maintaining vascular homeostasis through phenotype-dependent regulation of vascular tone, blood pressure, and hemodynamics ...
Li J +8 more
europepmc +2 more sources
Therapeutic and pharmacological potential of Tanshinones against lung cancer: A systematic review
Phytomedicine Plus, 2022 Background: Lung cancer is the most prevalent of all cancers, causing the highest number of cancer-related deaths in men and the second-highest number in women worldwide.
Syed Sahajada Mahafujul Alam +4 more
doaj +1 more source
Tanshinone IIA Stimulates Erythrocyte Phosphatidylserine Exposure [PDF]
Cellular Physiology and Biochemistry, 2012 Tanshinone IIA, an antimicrobial, antioxidant, antianaphylactic, antifibrotic, vasodilating, antiatherosclerotic, organo-protective and antineoplastic component from the rhizome of Salvia miltiorrhiza, is known to trigger apoptosis of tumor cells. Tanshinone IIA is effective in part through mitochondrial depolarization and altered gene expression ...
ZELENAK C. +9 more
openaire +5 more sources
Metabolic profiles and cDNA-AFLP analysis of Salvia miltiorrhiza and Salvia castanea Diel f. tomentosa Stib. [PDF]
PLoS ONE, 2012 Plants of the genus Salvia produce various types of phenolic compounds and tanshinones which are effective for treatment of coronary heart disease. Salvia miltiorrhiza and S. castanea Diels f. tomentosa Stib are two important members of the genus.
Dongfeng Yang +7 more
doaj +1 more source