Results 41 to 50 of about 43,685,384 (257)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Arabic / English / Arabic translation : shifts of cohesive markers in the translation of argumentative texts : a contrastive Arabic-English text-linguistic study [PDF]
, 2004 EThOS - Electronic Theses Online ServiceGBUnited ...
Al-Amri, Khalid Hadi
core
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Predicting drug-target interactions using drug-drug interactions. [PDF]
PLoS ONE, 2013 Computational methods for predicting drug-target interactions have become important in drug research because they can help to reduce the time, cost, and failure rates for developing new drugs.
Shinhyuk Kim, Daeyong Jin, Hyunju Lee
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
مجلة الآداب, 2019 People have a tendency to, instead of saying harsh and brunt things, express what they think in suitable mitigatingways to make the communication more smooth and comfort. Euphemism is one of the effective ways of communication for that purpose.
Yaghdan R. Mahdi, Mayada R. Eesa
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Vision: Journal for Language and Foreign Language Learning, 2021 As quality is one of the most important aspects of translation studies, the researchers aim at analyzing the quality of the Persian translation of The Alchemist by Paulo Coelho, which is one of the best-selling novels in the world based on House’s (1997)
Sheida Ronagh Zadeh +2 more
doaj +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Auch wir lieben bekanntermaßen Daten. Daher ist Text+ natürlich auch bei der diesjährigen Love Data Week dabei, die vom 12. bis 16. Februar stattfindet.
Text+ Blog-Redaktion
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