Results 1 to 10 of about 297,624 (212)
Riboflavin-Targeted Drug Delivery [PDF]
Cancers, 2020 Active targeting can improve the retention of drugs and drug delivery systems in tumors, thereby enhancing their therapeutic efficacy. In this context, vitamin receptors that are overexpressed in many cancers are promising targets. In the last decade, attention and research were mainly centered on vitamin B9 (folate) targeting; however, the focus is ...
Milita Darguzyte +3 more
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Mitochondria-Targeted Drug Delivery [PDF]
Pharmaceutics, 2022 Mitochondria, organelles surrounded by a double membrane and with their own small genome, are the cells’ energy centres [...]
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Hypoxia-targeted drug delivery [PDF]
Chemical Society Reviews, 2019 Hypoxia is a state of low oxygen tension found in numerous solid tumours.
Amit Sharma +6 more
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Pharmaceutics, 2022 At present, brain diseases affect one in six people worldwide, and they include a wide range of neurological diseases from Alzheimer’s and Parkinson’s diseases to epilepsy, brain injuries, brain cancer, neuroinfections and strokes [...]
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Echogenic lipsomes for targeted drug delivery [PDF]
2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2009 Echogenic immunoliposomes (ELIP) are under development to enable ultrasound-controlled drug delivery. Mechanistic studies in vitro have revealed that stable cavitation is correlated with enhanced recombinant tissue Plasminogen Activator (rt-PA) thrombolysis, yet strategies to optimize the occurrence of such bubble activity and avoid potential harmful ...
Christy K. Holland, David D. McPherson
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Nanotechnology in Targeted Drug Delivery
International Journal of Molecular Sciences, 2023 The use of large sized materials in drug delivery raises several challenges, including in vivo stability, poor bioavailability/solubility/absorption, and issues with target-specific delivery, in addition to the side effects of the delivered drugs [...]
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Targeted Drug Delivery and Theragnostics
Current Pharmaceutical Design, 2020 openaire +2 more sources
Aptamers for Targeted Drug Delivery
Pharmaceuticals, 2010 Aptamers are a class of therapeutic oligonucleotides that form specific three-dimensional structures that are dictated by their sequences. They are typically generated by an iterative screening process of complex nucleic acid libraries employing a process termed Systemic Evolution of Ligands by Exponential Enrichment (SELEX).
Partha Ray, Rebekah R. White
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Polymers for colon targeted drug delivery
Indian Journal of Pharmaceutical Sciences, 2010 The colon targeted drug delivery has a number of important implications in the field of pharmacotherapy. Oral colon targeted drug delivery systems have recently gained importance for delivering a variety of therapeutic agents for both local and systemic administration.
Rajpurohit, H. +3 more
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Materials Today, 2005 The concept of targeted drugs is not new, but dates back to 1906 when Ehrlich 1 first postulated the ‘magic bullet’. The durability of this concept is a strong indication of its appeal, but the ‘magic bullet’ continues to be a challenge to implement in the clinic.
Fahmy, Tarek M. +3 more
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