Results 11 to 20 of about 4,076,090 (289)
Riboflavin-Targeted Drug Delivery [PDF]
Cancers, 2020 Active targeting can improve the retention of drugs and drug delivery systems in tumors, thereby enhancing their therapeutic efficacy. In this context, vitamin receptors that are overexpressed in many cancers are promising targets. In the last decade, attention and research were mainly centered on vitamin B9 (folate) targeting; however, the focus is ...
Milita Darguzyte +3 more
openaire +3 more sources
Anticancer drug delivery with transferrin targeted polymeric chitosan vesicles [PDF]
, 2004 The study reports the initial biological evaluation of targeted polymeric glycol chitosan vesicles as carrier systems for doxorubicin (Dox). Transferrin (Tf) was covalently bound to the Dox-loaded palmitoylated glycol chitosan (GCP) vesicles using ...
Dufès, Christine +5 more
core +4 more sources
Mitochondria-Targeted Drug Delivery [PDF]
Pharmaceutics, 2022 Mitochondria, organelles surrounded by a double membrane and with their own small genome, are the cells’ energy centres [...]
openaire +3 more sources
Release of functional dexamethasone by intracellular enzymes: A modular peptide-based strategy for ocular drug delivery [PDF]
, 2020 Tissue barriers limit drug delivery in the eye. Therefore, retinal diseases are treated with intravitreal injections. Delivery systems with reduced dosing frequency and/or cellular drug delivery properties are needed.
Sadeghi, Amir +7 more
core +1 more source
Sequential Drug Delivery in Targeted Cancer Therapy
, 2022 Cancer is a major public health problem and one of the leading causes of death. However, traditional cancer therapy may damage normal cells and cause side effects.
Jiang, Lingling +11 more
core +1 more source
The roles of microRNA families in hepatic fibrosis
Cell & Bioscience, 2017 When hepatocytes are damaged severely, a variety of signaling pathways will be triggered by inflammatory factors and cytokines involving in the process of hepatic fibrosis.
Xue-Ping Jiang +4 more
doaj +1 more source
Antibiotics, 2022 Bacterial resistance is a growing global concern necessitating the discovery and development of antibiotics effective against the drug-resistant bacterial strain.
Muhammad Imran Sajid +3 more
doaj +1 more source
Hypoxia-targeted drug delivery [PDF]
Chemical Society Reviews, 2019 Hypoxia is a state of low oxygen tension found in numerous solid tumours.
Amit Sharma +6 more
openaire +2 more sources
Niosomes as Nano-carrier Based Targeted Drug Delivery System [PDF]
, 2021 Niosomes are considered as novel nano-carrier in the drug delivery systems. These are much more stable than other nano-carriers like liposomes and nanoparticles. It is an example for targeted and control release of medication.
Nair, Smitha K. +3 more
core +1 more source
Click-Free Synthesis of a Multivalent Tricyclic Peptide as a Molecular Transporter
Pharmaceutics, 2020 The cellular delivery of cell-impermeable and water-insoluble molecules remains an ongoing challenge to overcome. Previously, we reported amphipathic cyclic peptides c[WR]4 and c[WR]5 consisting of alternate arginine and tryptophan residues as nuclear ...
Sumit Kumar +5 more
doaj +1 more source