Results 21 to 30 of about 4,076,090 (289)
The miR-290-295 cluster as multi-faceted players in mouse embryonic stem cells
Cell & Bioscience, 2017 Increasing evidence indicates that embryonic stem cell specific microRNAs (miRNAs) play an essential role in the early development of embryo. Among them, the miR-290-295 cluster is the most highly expressed in the mouse embryonic stem cells and involved ...
Kai Yuan +4 more
doaj +1 more source
Brain-Targeted Drug Delivery System: A Novel Approach [PDF]
, 2022 A targeted drug delivery system is based on a technique that continuously administers a predetermined dosage of a therapeutic agent to a sick location of the body.
Chahar, Rajeev Kumar +3 more
core +1 more source
Polysaccharides in Ocular Drug Delivery [PDF]
, 2019 Polysaccharides, such as cellulose, hyaluronic acid, alginic acid, and chitosan, as well as polysaccharide derivatives, have been successfully used to augment drug delivery in the treatment of ocular pathologies.
Arto Urtti +9 more
core +1 more source
Pharmaceutics, 2022 At present, brain diseases affect one in six people worldwide, and they include a wide range of neurological diseases from Alzheimer’s and Parkinson’s diseases to epilepsy, brain injuries, brain cancer, neuroinfections and strokes [...]
openaire +3 more sources
Echogenic lipsomes for targeted drug delivery [PDF]
2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2009 Echogenic immunoliposomes (ELIP) are under development to enable ultrasound-controlled drug delivery. Mechanistic studies in vitro have revealed that stable cavitation is correlated with enhanced recombinant tissue Plasminogen Activator (rt-PA) thrombolysis, yet strategies to optimize the occurrence of such bubble activity and avoid potential harmful ...
Christy K. Holland, David D. McPherson
openaire +2 more sources
Theranostic barcoded nanoparticles for personalized cancer medicine
Nature Communications, 2016 Determining the most effective treatment for each cancer patient is a key challenge in cancer therapy. In this article, the authors show, in a mouse model of breast cancer, that DNA barcoded nanoparticles can be used for pre-screening the efficacy of ...
Zvi Yaari +11 more
doaj +1 more source
Aptamers for Targeted Drug Delivery
Pharmaceuticals, 2010 Aptamers are a class of therapeutic oligonucleotides that form specific three-dimensional structures that are dictated by their sequences. They are typically generated by an iterative screening process of complex nucleic acid libraries employing a process termed Systemic Evolution of Ligands by Exponential Enrichment (SELEX).
Ray, White
openaire +3 more sources
Osteoblast Differentiation of Human Dental Pulp Stem Cells with Dexamethasone in-situ Forming Implant [PDF]
Journal of Mashhad Dental School, 2021 Introduction: Dental pulp stem cells (DPSCs) are known as multipotent stem cells which differentiate into three different cell lines, including osteocytes, chondrocytes, and adipocytes.
Zahra Tayarani-Najaran +5 more
doaj +1 more source
Targeted Drug Delivery and Theragnostics
Current Pharmaceutical Design, 2020 openaire +2 more sources
Nanotechnology in Targeted Drug Delivery
International Journal of Molecular Sciences, 2023 The use of large sized materials in drug delivery raises several challenges, including in vivo stability, poor bioavailability/solubility/absorption, and issues with target-specific delivery, in addition to the side effects of the delivered drugs [...]
openaire +2 more sources