Results 31 to 40 of about 1,487,644 (266)
Click-Free Synthesis of a Multivalent Tricyclic Peptide as a Molecular Transporter
Pharmaceutics, 2020 The cellular delivery of cell-impermeable and water-insoluble molecules remains an ongoing challenge to overcome. Previously, we reported amphipathic cyclic peptides c[WR]4 and c[WR]5 consisting of alternate arginine and tryptophan residues as nuclear ...
Sumit Kumar +5 more
doaj +1 more source
Antibiotics, 2022 Bacterial resistance is a growing global concern necessitating the discovery and development of antibiotics effective against the drug-resistant bacterial strain.
Muhammad Imran Sajid +3 more
doaj +1 more source
Journal of Multidisciplinary Healthcare, 2021 Nanomedicine is an advanced version of Paul Ehrlich’s “magic bullet” concept. Targeted drug delivery is a system of specifying the drug moiety directly into its targeted body area (organ, cellular, and subcellular level of specific tissue) to overcome ...
Ashagrachew Tewabe +4 more
semanticscholar +1 more source
The miR-290-295 cluster as multi-faceted players in mouse embryonic stem cells
Cell & Bioscience, 2017 Increasing evidence indicates that embryonic stem cell specific microRNAs (miRNAs) play an essential role in the early development of embryo. Among them, the miR-290-295 cluster is the most highly expressed in the mouse embryonic stem cells and involved ...
Kai Yuan +4 more
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Nano based drug delivery systems: recent developments and future prospects
Journal of Nanobiotechnology, 2018 Nanomedicine and nano delivery systems are a relatively new but rapidly developing science where materials in the nanoscale range are employed to serve as means of diagnostic tools or to deliver therapeutic agents to specific targeted sites in a ...
J. Patra +11 more
semanticscholar +1 more source
Cell Membrane-Cloaked Nanotherapeutics for Targeted Drug Delivery
International Journal of Molecular Sciences, 2022 Cell membrane cloaking technique is bioinspired nanotechnology that takes advantage of naturally derived design cues for surface modification of nanoparticles.
Na-Hyun Lee +4 more
semanticscholar +1 more source
Effects of polyethylene glycol on the surface of nanoparticles for targeted drug delivery.
Nanoscale, 2021 The rapid development of drug nanocarriers has benefited from the surface hydrophilic polymers of particles, which has improved the pharmacokinetics of the drugs.
Liwang Shi +9 more
semanticscholar +1 more source
Theranostic barcoded nanoparticles for personalized cancer medicine
Nature Communications, 2016 Determining the most effective treatment for each cancer patient is a key challenge in cancer therapy. In this article, the authors show, in a mouse model of breast cancer, that DNA barcoded nanoparticles can be used for pre-screening the efficacy of ...
Zvi Yaari +11 more
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Chitosan-Based Nanoparticles of Targeted Drug Delivery System in Breast Cancer Treatment
Polymers, 2021 Breast cancer remains one of the world’s most dangerous diseases because of the difficulty of finding cost-effective and specific targets for effective and efficient treatment methods.
Y. Herdiana +4 more
semanticscholar +1 more source
Osteoblast Differentiation of Human Dental Pulp Stem Cells with Dexamethasone in-situ Forming Implant [PDF]
Journal of Mashhad Dental School, 2021 Introduction: Dental pulp stem cells (DPSCs) are known as multipotent stem cells which differentiate into three different cell lines, including osteocytes, chondrocytes, and adipocytes.
Zahra Tayarani-Najaran +5 more
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