Results 31 to 40 of about 4,076,090 (289)
Nanovesicles for tumor-targeted drug delivery [PDF]
, 2022 Cancer is one of the most important burdens for the health systems worldwide due to cancer-related deaths associated with late diagnosis and treatment toxicities.
İlhan, Miray +11 more
core +2 more sources
Preparation and evaluation of electrospun nanofibers containing pectin and time-dependent polymers aimed for colonic drug delivery of celecoxib [PDF]
Nanomedicine Journal, 2016 Objective(s):The aim of this study was to prepare electrospun nanofibers of celecoxib using combination of time-dependent polymers with pectin to achieve a colon-specific drug delivery system for celecoxib.
A. Akhgari, M. Hossein Rotubati
doaj +1 more source
Preparation and in-vitro evaluation of fluorometholone cubosomes for ocular delivery [PDF]
Nanomedicine Journal, 2023 Objective(s): In this study, ocular drug delivery systems with a dispersed lipid liquid crystal (cubosomes) containing fluorometholone were used for sustained release and increased permeability to the eye.Materials and Methods: To obtain the best ...
Bizhan Malaekeh-Nikouei +4 more
doaj +1 more source
Tumor-targeted delivery of siRNA using fatty acyl-CGKRK peptide conjugates
Scientific Reports, 2017 Tumor-targeted carriers provide efficient delivery of chemotherapeutic agents to tumor tissue. CGKRK is one of the well-known tumor targeting peptides with significant specificity for angiogenic blood vessels and tumor cells. Here, we designed fatty acyl
Meenakshi Sharma +5 more
doaj +1 more source
Synthetic cells with self-activating optogenetic proteins communicate with natural cells
Nature Communications, 2022 Synthetic biology and engineering approaches are harnessed to incorporate new capabilities in synthetic cells. Here, the authors designed bioluminescent signaling mechanisms for intracellular and intercellular synthetic-to-natural cell communication.
Omer Adir +15 more
doaj +1 more source
Pharmaceuticals, 2023 Fungal infections remain a significant concern for human health. The emergence of microbial resistance, the improper use of antimicrobial drugs, and the need for fewer toxic antifungal treatments in immunocompromised patients have sparked substantial ...
Naiera M. Helmy, Keykavous Parang
doaj +1 more source
Preparation and Characterization of Undecylenoyl Phenylalanine Loaded-Nanostructure Lipid Carriers (NLCs) as a New α-MSH Antagonist and Antityrosinase Agent [PDF]
Advanced Pharmaceutical Bulletin, 2023 Purpose: The aim of this study was to characterize the undecylenoyl phenylalanine (Sepiwhite (SEPI))-loaded nanostructured lipid carriers (NLCs) as a new antimelanogenesis compound.
Mohadeseh Sadat Vaziri +5 more
doaj +1 more source
Targeted Based Drug Delivery System for Colon Cancer [PDF]
, 2020 Regardless of so many advancements in the treatment, colon cancer still stands third in cancer-related deaths worldwide. Toxicity associated with conventional drugs is one of the major problems associated with chemotherapy.
Kaur, Veerpal +3 more
core +1 more source
Molecules, 2018 Linear (HR)n and cyclic [HR]n peptides (n = 4,5) containing alternate arginine and histidine residues were synthesized. The peptides showed 0–15% cytotoxicity at 5–100 µM in human ovarian adenocarcinoma (SK-OV-3) cells while they ...
Naglaa Salem El-Sayed +7 more
doaj +1 more source
Molecules, 2020 Remdesivir is a nucleotide prodrug that is currently undergoing extensive clinical trials for the treatment of COVID-19. The prodrug is metabolized to its active triphosphate form and interferes with the action of RNA-dependent RNA polymerase of SARS-COV-
Keykavous Parang +3 more
doaj +1 more source