Results 61 to 70 of about 3,310,810 (118)

RhoBTB3 Functions as a Novel Regulator of Autophagy by Suppressing AMBRA1 Stability

Cells
Autophagy is essential for cell survival and cellular homeostasis under various stress conditions. Therefore, autophagy dysfunction is associated with the pathogenesis of various human diseases. We explored the regulatory role of RhoBTB3 in autophagy and
Kyungho Kim, Dong-Gun Kim, Youn-Jae Kim
doaj   +1 more source

Endogenous Coriobacteriaceae enriched by a high-fat diet promotes colorectal tumorigenesis through the CPT1A-ERK axis

npj Biofilms and Microbiomes
A high-fat diet (HFD) may be linked to an increased colorectal cancer (CRC) risk. Stem cell proliferation and adipokine release under inflammatory and obese conditions are the main factors regulating CRC progression.
Qiulin Tang, Huixi Huang, Huanji Xu, Hongwei Xia, Chenliang Zhang, Di Ye, Feng Bi   +6 more
doaj   +1 more source

BRD4 modulator ZL0580 and LEDGINs additively block and lock HIV-1 transcription

Nature Communications
The persistence of HIV-1 in a latent state within long-lived immune cells remains a major barrier to a cure for HIV-1 infection. The “block-and-lock” strategy aims to silence the HIV-1 provirus permanently using latency promoting agents (LPAs).
Eline Pellaers, Julie Janssens, Lore Wils, Alexe Denis, Anayat Bhat, Siska Van Belle, Da Feng, Frauke Christ, Peng Zhan, Zeger Debyser   +9 more
doaj   +1 more source

The Mechanism and Research Progress of Skin Microbiota in Pathogenesis of Acne

Dermatology Research and Practice
Acne is a chronic inflammatory skin disease of the sebaceous unit of the facial hair follicle that occurs mainly in adolescence. The four major pathogenesis of acne are excessive secretion of sebum by sebaceous glands, abnormal keratosis of sebaceous ...
Xinwei Li, Juan Jin
doaj   +1 more source

Other title: What does the Occupational Therapy, Physical Therapy, and Athletic Trainers Board say about telehealth?

, 2020
"Created: 3/16/2020..."--Document properties ...
Ohio Occupational Therapy, Physical Therapy, and Athletic Trainers Board
core  

Targeted Therapy in Oncology [PDF]

Medical Journal Armed Forces India, 2006
B K, Mishra, Purvish M, Parikh
openaire   +2 more sources

miR-196a-5p promotes the proliferation, migration, and invasion of esophageal squamous cell carcinoma by targeting LIFR

Cancer Cell International
Background Esophageal squamous cell carcinoma (ESCC) is a prevalent and aggressive malignancy. While microRNAs (miRNAs) are known to play a critical regulatory role in the occurrence and progression of ESCC, the underlying mechanisms remain incompletely ...
Junhe Zhang, Fan Liang, Weifeng Wang, Yiran Qin, Xiaoshu Hu   +4 more
doaj   +1 more source

FVTF inhibits hepatocellular carcinoma stem properties via targeting DNMT1/miR-34a-5p/FoxM1 axis

Chinese Medicine
Background Fructus Viticis Total Flavonoids (FVTF) is a novel candidate preparation that possesses anticancer activity. However, the role and mechanism of FVTF-inhibiting human hepatocellular carcinoma (HCC) cell stem properties is unclear.
Xiao-Cheng Cao, Jinwu Peng, Ye-Bei Qiu, Wei Zhu, Jian-Guo Cao, Hui Zou, Zheng-Zheng Yu, Di Wu, Shan-Shan Lu, Wei Huang, Hong Yi, Zhi-Qiang Xiao   +11 more
doaj   +1 more source

Targeting the value of targeted therapy

Oncotarget, 2017
Paggio, Joseph C. Del, Sullivan, Richard, Booth, Christopher M.   +2 more
openaire   +2 more sources

Eupatilin-derived compounds enhance antitumor activity and doxorubicin efficacy in triple-negative breast cancer

Frontiers in Oncology
PurposeTriple-negative breast cancer (TNBC) has limited therapeutic options. We evaluated the anticancer activities of the Eupatilin derivatives ONG41008 and ONG41003 and their potential to enhance doxorubicin efficacy.Materials and methodsAnticancer ...
Choong-Jae Lee, Choong-Jae Lee, Jinyoung Park, Yanghee Choi, Sung Hoon Sim, Sun-Young Kong, Sun-Young Kong, Sun-Young Kong   +7 more
doaj   +1 more source