Results 21 to 30 of about 1,199,889 (280)
The effect of Staphylococcus aureus carriage in late pregnancy on antibody levels to staphylococcal toxins in cord blood and breast milk. [PDF]
We investigated the effect of carriage of Staphylococcus aureus in the later stages of pregnancy on levels of antibody specific to the S. aureus toxins, staphylococcal enterotoxin B (SEB), staphylococcal enterotoxin C (SEC) and toxic shock syndrome toxin-
Morris, James A. +3 more
core +4 more sources
Environmental toxins have the potential to disrupt the animal gut microbiome (AGM), which can lead to various gut-associated diseases such as inflammatory bowel disease (IBD) and colorectal cancer.
Dinesh Nalage +7 more
doaj +1 more source
First Published in 1992. The last decade of the twentieth century has seen an unprecedented advocacy for the preservation of a safe environment, and the prevention of ill-health from toxic chemicals. Human activity, however, is responsible for introducing new toxins into the environment.
Watters, Dianne +3 more
openaire +2 more sources
Toxins, Targets, and Triggers: An Overview of Toxin-Antitoxin Biology [PDF]
Bacterial toxin-antitoxin (TA) modules are abundant genetic elements that encode a toxin protein capable of inhibiting cell growth and an antitoxin that counteracts the toxin. The majority of toxins are enzymes that interfere with translation or DNA replication, but a wide variety of molecular activities and cellular targets have been described ...
Harms, Alexander +3 more
openaire +5 more sources
The epidermal growth factor receptor (EGFR) was found to be a valuable target on prostate cancer (PCa) cells. However, EGFR inhibitors mostly failed in clinical studies with patients suffering from PCa.
Alexandra Fischer +4 more
doaj +1 more source
Microcystins and nodularins, produced naturally by certain species of cyanobacteria, have been found to accumulate in aquatic foodstuffs such as fish and shellfish, resulting in a risk to the health of the seafood consumer.
Andrew D. Turner +10 more
doaj +1 more source
Channel-Forming Bacterial Toxins in Biosensing and Macromolecule Delivery
To intoxicate cells, pore-forming bacterial toxins are evolved to allow for the transmembrane traffic of different substrates, ranging from small inorganic ions to cell-specific polypeptides. Recent developments in single-channel electrical recordings,
Philip A. Gurnev +1 more
doaj +1 more source
Glycosylated Triterpenoids as Endosomal Escape Enhancers in Targeted Tumor Therapies
Protein-based targeted toxins play an increasingly important role in targeted tumor therapies. In spite of their high intrinsic toxicity, their efficacy in animal models is low.
Hendrik Fuchs +6 more
doaj +1 more source
Cnidarian Toxins Acting on Voltage-Gated Ion Channels
: Voltage-gated ion channels generate electrical activity in excitable cells. As such, they are essential components of neuromuscular and neuronal systems, and are targeted by toxins from a wide variety of phyla, including the cnidarians. Here, we review
Robert M. Greenberg, Shanta M. Messerli
doaj +1 more source
Gut-Derived Metabolites and Their Role in Immune Dysfunction in Chronic Kidney Disease
Several of the uremic toxins, which are difficult to remove by dialysis, originate from the gut bacterial metabolism. This opens opportunities for novel targets trying to decrease circulating levels of these toxins and their pathophysiological effects ...
Griet Glorieux +2 more
doaj +1 more source

