Results 21 to 30 of about 1,199,889 (280)

The effect of Staphylococcus aureus carriage in late pregnancy on antibody levels to staphylococcal toxins in cord blood and breast milk. [PDF]

open access: yes, 2008
We investigated the effect of carriage of Staphylococcus aureus in the later stages of pregnancy on levels of antibody specific to the S. aureus toxins, staphylococcal enterotoxin B (SEB), staphylococcal enterotoxin C (SEC) and toxic shock syndrome toxin-
Morris, James A.   +3 more
core   +4 more sources

The impact of environmental toxins on the animal gut microbiome and their potential to contribute to disease

open access: yesFood Chemistry Advances, 2023
Environmental toxins have the potential to disrupt the animal gut microbiome (AGM), which can lead to various gut-associated diseases such as inflammatory bowel disease (IBD) and colorectal cancer.
Dinesh Nalage   +7 more
doaj   +1 more source

Toxins and Targets

open access: yes, 2022
First Published in 1992. The last decade of the twentieth century has seen an unprecedented advocacy for the preservation of a safe environment, and the prevention of ill-health from toxic chemicals. Human activity, however, is responsible for introducing new toxins into the environment.
Watters, Dianne   +3 more
openaire   +2 more sources

Toxins, Targets, and Triggers: An Overview of Toxin-Antitoxin Biology [PDF]

open access: yesMolecular Cell, 2018
Bacterial toxin-antitoxin (TA) modules are abundant genetic elements that encode a toxin protein capable of inhibiting cell growth and an antitoxin that counteracts the toxin. The majority of toxins are enzymes that interfere with translation or DNA replication, but a wide variety of molecular activities and cellular targets have been described ...
Harms, Alexander   +3 more
openaire   +5 more sources

Pseudomonas Exotoxin A Based Toxins Targeting Epidermal Growth Factor Receptor for the Treatment of Prostate Cancer

open access: yesToxins, 2020
The epidermal growth factor receptor (EGFR) was found to be a valuable target on prostate cancer (PCa) cells. However, EGFR inhibitors mostly failed in clinical studies with patients suffering from PCa.
Alexandra Fischer   +4 more
doaj   +1 more source

A Feasibility Study into the Production of a Mussel Matrix Reference Material for the Cyanobacterial Toxins Microcystins and Nodularins

open access: yesToxins, 2022
Microcystins and nodularins, produced naturally by certain species of cyanobacteria, have been found to accumulate in aquatic foodstuffs such as fish and shellfish, resulting in a risk to the health of the seafood consumer.
Andrew D. Turner   +10 more
doaj   +1 more source

Channel-Forming Bacterial Toxins in Biosensing and Macromolecule Delivery

open access: yesToxins, 2014
To intoxicate cells, pore-forming bacterial toxins are evolved to allow for the transmembrane traffic of different substrates, ranging from small inorganic ions to cell-specific polypeptides. Recent developments in single-channel electrical recordings,
Philip A. Gurnev   +1 more
doaj   +1 more source

Glycosylated Triterpenoids as Endosomal Escape Enhancers in Targeted Tumor Therapies

open access: yesBiomedicines, 2017
Protein-based targeted toxins play an increasingly important role in targeted tumor therapies. In spite of their high intrinsic toxicity, their efficacy in animal models is low.
Hendrik Fuchs   +6 more
doaj   +1 more source

Cnidarian Toxins Acting on Voltage-Gated Ion Channels

open access: yesMarine Drugs, 2006
: Voltage-gated ion channels generate electrical activity in excitable cells. As such, they are essential components of neuromuscular and neuronal systems, and are targeted by toxins from a wide variety of phyla, including the cnidarians. Here, we review
Robert M. Greenberg, Shanta M. Messerli
doaj   +1 more source

Gut-Derived Metabolites and Their Role in Immune Dysfunction in Chronic Kidney Disease

open access: yesToxins, 2020
Several of the uremic toxins, which are difficult to remove by dialysis, originate from the gut bacterial metabolism. This opens opportunities for novel targets trying to decrease circulating levels of these toxins and their pathophysiological effects ...
Griet Glorieux   +2 more
doaj   +1 more source

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