Results 21 to 30 of about 156,135 (285)
Glabralysins, potential New β-pore-forming toxin family members from the schistosomiasis vector snail biomphalaria glabrata [PDF]
, 2020 Biomphalaria glabrata is a freshwater Planorbidae snail. In its environment, this mollusk faces numerous microorganisms or pathogens, and has developed sophisticated innate immune mechanisms to survive.
Crickmore, Neil +6 more
core +3 more sources
Toxins, 2022 Microcystins and nodularins, produced naturally by certain species of cyanobacteria, have been found to accumulate in aquatic foodstuffs such as fish and shellfish, resulting in a risk to the health of the seafood consumer.
Andrew D. Turner +10 more
doaj +1 more source
Toxins, 2020 The epidermal growth factor receptor (EGFR) was found to be a valuable target on prostate cancer (PCa) cells. However, EGFR inhibitors mostly failed in clinical studies with patients suffering from PCa.
Alexandra Fischer +4 more
doaj +1 more source
Channel-Forming Bacterial Toxins in Biosensing and Macromolecule Delivery
Toxins, 2014 To intoxicate cells, pore-forming bacterial toxins are evolved to allow for the transmembrane traffic of different substrates, ranging from small inorganic ions to cell-specific polypeptides. Recent developments in single-channel electrical recordings,
Philip A. Gurnev +1 more
doaj +1 more source
The role of mycotoxins in the human exposome: Application of mycotoxin biomarkers in exposome-health studies [PDF]
, 2018 Mycotoxins are secondary metabolites produced by fungi that may contaminate different foods intended for human consumption, resulting in a widespread exposure worldwide. The novel exposome paradigm has the ambition to decipher the different environmental
Cano Sancho, German +3 more
core +4 more sources
A double safety lock tumor-specific device for suicide gene therapy in breast cancer [PDF]
, 2020 Producción CientíficaThe complexity and continuous evolution of cancer make the design of novel strategies of treatment a constant challenge in biomedicine.
Arias Vallejo, Francisco Javier +5 more
core +2 more sources
, 2022 First Published in 1992. The last decade of the twentieth century has seen an unprecedented advocacy for the preservation of a safe environment, and the prevention of ill-health from toxic chemicals. Human activity, however, is responsible for introducing new toxins into the environment.
Watters, Dianne +3 more
openaire +2 more sources
Glycosylated Triterpenoids as Endosomal Escape Enhancers in Targeted Tumor Therapies
Biomedicines, 2017 Protein-based targeted toxins play an increasingly important role in targeted tumor therapies. In spite of their high intrinsic toxicity, their efficacy in animal models is low.
Hendrik Fuchs +6 more
doaj +1 more source
The isolation and characterisation of temperature-dependent Ricin A chain molecules in Saccharomyces cerevisiae. [PDF]
, 2007 Ricin is a heterodimeric plant protein that is potently toxic to mammalian cells. Toxicity results from the catalytic depurination of eukaryotic ribosomes by ricin A chain (RTA) that follows toxin endocytosis to, and translocation across, the ...
Allen +41 more
core +1 more source
Expanded Haemodialysis as a Current Strategy to Remove Uremic Toxins
Toxins, 2021 Chronic kidney disease (CKD) is characterized by the retention of solutes named uremic toxins, which strongly associate with high morbidity and mortality. Mounting evidence suggests that targeting uremic toxins and/or their pathways may decrease the risk
Paola Ciceri, Mario Cozzolino
doaj +1 more source