Results 1 to 10 of about 50 (50)
Neurotrophins in Zebrafish Taste Buds
Animals, 2022 The neurotrophin family is composed of nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), Neurotrophin 3 (NT3) and NT4. These neurotrophins regulate several crucial functions through the activation of two types of transmembrane receptors, namely p75, which binds all neurotrophins with a similar affinity, and tyrosine kinase (Trk ...
Gatta, Claudia +4 more
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Taste Receptors beyond Taste Buds
International Journal of Molecular Sciences, 2022 Taste receptors are responsible for detecting their ligands not only in taste receptor cells (TRCs) but also in non-gustatory organs. For several decades, many research groups have accumulated evidence for such “ectopic” expression of taste receptors. More recently, some of the physiologic functions (apart from taste) of these ectopic taste receptors ...
Ki, Su Young, Jeong, Yong Taek
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A taste for ATP: neurotransmission in taste buds [PDF]
Frontiers in Cellular Neuroscience, 2013 Not only is ATP a ubiquitous source of energy but it is also used widely as an intercellular signal. For example, keratinocytes release ATP in response to numerous external stimuli including pressure, heat, and chemical insult. The released ATP activates purinergic receptors on nerve fibers to generate nociceptive signals.
Sue C. Kinnamon, Thomas E. Finger
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Fingerprinting taste buds: intermediate filaments and their implication for taste bud formation [PDF]
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2000 Intermediate filaments in taste organs of terrestrial (human and chick) as well as aquatic (Xenopus laevis) species were detected using immunohistochemistry and electron microscopy. During development, the potential importance of the interface between the taste bud primordium and non–gustatory, adjacent tissues is evidenced by the distinct ...
Judith R. Ganchrow +3 more
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Neural induction of taste buds [PDF]
Journal of Comparative Neurology, 1987 AbstractBilateral innervation allows more than 80% of the 610 vallate taste buds to survive removal of one IXth nerve in adult rats. Removal of both IXth nerves in neonatal or adult rats results in the absence of taste buds. In studying development, we found that removing or crushing one IXth nerve in three‐day‐old neonates profoundly decreased the ...
Hosley, Mark A. +2 more
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Taste Bud Connectome: Implications for Taste Information Processing [PDF]
The Journal of Neuroscience, 2021 Taste buds contain multiple cell types, two of which mediate transduction of specific taste qualities: Type III cells transduce sour while Type II cells transduce either sweet, or bitter or umami. In order to discern the degree of interaction between different cell types and specificity of connectivity with the afferent nerve fibers (NFs), we employed ...
Courtney E. Wilson +5 more
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Taste isn't just for taste buds anymore [PDF]
F1000 Biology Reports, 2011 Taste is a discriminative sense involving specialized receptor cells of the oral cavity (taste buds) and at least two distinct families of G protein-coupled receptor molecules that detect nutritionally important substances or potential toxins. Yet the receptor mechanisms that drive taste also are utilized by numerous systems throughout the body.
Thomas E. Finger, Sue C. Kinnamon
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Taste bud formation depends on taste nerves
eLife, 2019 It has been known for more than a century that, in adult vertebrates, the maintenance of taste buds depends on their afferent nerves. However, the initial formation of taste buds is proposed to be nerve-independent in amphibians, and evidence to the contrary in mammals has been endlessly debated, mostly due to indirect and incomplete means to impede ...
Jean-François Brunet +4 more
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The Taste of Monosodium Glutamate: Membrane Receptors in Taste Buds [PDF]
The Journal of Neuroscience, 1996 Receptor proteins for photoreception have been studied for several decades. More recently, putative receptors for olfaction have been isolated and characterized. In contrast, no receptors for taste have been identified yet by molecular cloning. This report describes experiments aimed at identifying a receptor responsible for the taste of monosodium ...
Chaudhari, Nirupa +6 more
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Inflammation and Taste Disorders [PDF]
Annals of the New York Academy of Sciences, 2009 Taste disorders, including taste distortion and taste loss, negatively impact general health and quality of life. To understand the underlying molecular and cellular mechanisms, we set out to identify inflammation‐related molecules in taste tissue and to assess their role in the development of taste dysfunctions.
Hong Wang +4 more
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