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The highly diverse TATA box-binding proteins among protists: A review
Molecular and Biochemical Parasitology, 2020Transcription is the first step of gene expression regulation and is a fundamental mechanism for establishing the viability and development of a cell. The TATA box-binding protein (TBP) interaction with a TATA box in a promoter is one of the best studied mechanisms in transcription initiation. TBP is a transcription factor that is highly conserved from
Olivia, Parra-Marín +3 more
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Biochemistry, 2002
Previous work has shown that binding of the TATA box binding protein (TBP) to the TATA box is a rate-limiting step during pre-initiation complex (PIC) formation. Although the transcription of eukaryotic genes normally proceeds in one direction, studies in solution have shown that TBP lacks the information necessary to orient itself on the TATA box ...
Alexis R, Kays, Alanna, Schepartz
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Previous work has shown that binding of the TATA box binding protein (TBP) to the TATA box is a rate-limiting step during pre-initiation complex (PIC) formation. Although the transcription of eukaryotic genes normally proceeds in one direction, studies in solution have shown that TBP lacks the information necessary to orient itself on the TATA box ...
Alexis R, Kays, Alanna, Schepartz
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Crystal structure of Methanococcus jannaschii TATA box‐binding protein
Genes to Cells, 2008As the archaeal transcription system consists of a eukaryotic‐type transcription apparatus and bacterial‐type regulatory transcription factors, analyses of the molecular interface between the transcription apparatus and regulatory transcription factors are critical to reveal the evolutionary change of the transcription system. TATA box‐binding protein (
Naruhiko, Adachi +4 more
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The TATA box regulates TATA-binding protein (TBP) dynamics in vivo
Trends in Biochemical Sciences, 2010Early work established the TATA box as the predominant DNA element of core promoters which directed accurate transcription initiation by RNA polymerase II. This element is recognized by TATA-binding protein (TBP), the central DNA-binding subunit of TFIID. In vitro binding and structural experiments indicate that TBP has a strong preference for TATA and
Laszlo, Tora, H Th Marc, Timmers
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An in vitro characterisation of the Trichomonas vaginalis TATA box-binding proteins (TBPs)
Parasitology Research, 2019The protozoan parasite Trichomonas vaginalis is a common human pathogen from one of the earliest-diverging eukaryotic lineages. At the transcriptional level, the highly conserved Inr element of RNA pol II-transcribed genes surrounds the transcription start site and is recognised by IBP39, a protein exclusive of T. vaginalis. Typical TATA boxes have not
Olivia Parra-Marín +6 more
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DNA Binding by TATA-box Binding Protein (TBP): A Molecular Dynamics Computational Study
Journal of Biomolecular Structure and Dynamics, 1996TATA-box binding protein (TBP) in a monomeric form and the complexes it forms with DNA have been elucidated with molecular dynamics simulations. Large TBP domain motions (bend and twist) are detected in the monomer as well as in the DNA complexes; these motions can be important for TBP binding of DNA.
K, Miaskiewicz, R L, Ornstein
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2.1 Å resolution refined structure of a TATA box-binding protein (TBP)
Nature Structural & Molecular Biology, 1994The three-dimensional structure of a TATA box-binding protein (TBP2) from Arabidopsis thaliana has been refined at 2.1 A resolution. TBPs are general eukaryotic transcription factors that participate in initiation of RNA synthesis by all three eukaryotic RNA polymerases.
D B, Nikolov, S K, Burley
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Spinocerebellar ataxia type 17 is caused by mutations in the TATA-box binding protein
The Cerebellum, 2007The spinocerebellar ataxia type 17 (SCA17) is characterized by cerebellar ataxia, dementia, and involuntary movements, including chorea and dystonia. In addition, psychiatric symptoms, pyramidal signs, and rigidity are common. MRI shows variable atrophy of the cerebrum, brainstem, and cerebellum.
Christine, Zühlke, Katrin, Bürk
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Nutrient regulation of TATA‐Box binding protein by O‐GlcNAcylation
The FASEB Journal, 2017O‐GlcNAcylation is a dynamic post‐translational modification that is responsive to nutrient avabilality via the hexosamine biosynthetic pathway and its endproduct UDP‐GlcNAc. O‐GlcNAcylation serves as a nutrient sensor to regulate the activities of many proteins involved in nearly all ...
Stephan Hardiville +5 more
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Archives of Microbiology, 2010
GvpE is the transcriptional activator of the gvp gene cluster involved in gas vesicle formation in Haloabacterium salinarum. A 20-nucleotide sequence is required for the GvpE-mediated activation of the two oppositely oriented gvp promoters, P ( A ) and P ( D ).
Katharina, Teufel, Felicitas, Pfeifer
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GvpE is the transcriptional activator of the gvp gene cluster involved in gas vesicle formation in Haloabacterium salinarum. A 20-nucleotide sequence is required for the GvpE-mediated activation of the two oppositely oriented gvp promoters, P ( A ) and P ( D ).
Katharina, Teufel, Felicitas, Pfeifer
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