An Experimental Verification of the Predicted Effects of Promoter TATA-Box Polymorphisms Associated with Human Diseases on Interactions between the TATA Boxes and TATA-Binding Protein [PDF]
PLoS ONE, 2013 Human genome sequencing has resulted in a great body of data, including a stunningly large number of single nucleotide polymorphisms (SNPs) with unknown phenotypic manifestations. Identification and comprehensive analysis of regulatory SNPs in human gene
Ludmila Savinkova +2 more
exaly +5 more sources
Study on Interaction Between TATA-Box Binding Protein (TBP), TATA-Box and Multiprotein Bridging Factor 1(MBF1) in Beauveria bassiana by Graphene-Based Electrochemical Biosensors [PDF]
Frontiers in Chemistry, 2020 The regulation of transcription level is an important step in gene expression process. Beauveria bassiana is a broad-spectrum insecticidal fungi widely used in the biologic control of arthropod.
Chi Song +7 more
doaj +2 more sources
On the Role of TATA Boxes and TATA-Binding Protein in Arabidopsis thaliana
Plants, 2023 For transcription initiation by RNA polymerase II (Pol II), all eukaryotes require assembly of basal transcription machinery on the core promoter, a region located approximately in the locus spanning a transcription start site (−50; +50 bp). Although Pol
L. K. Savinkova +2 more
doaj +3 more sources
The Association between Prolonged Jaundice and TATA Box Dinucleotide Repeats in Gilbert’s Syndrome [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: Jaundice is a common condition during the neonatal period. Prolonged jaundice occurs in a large number of breastfed infants, considering the impact of genetic factors on the incidence of jaundice.
Yadollah Zahed Pasha +4 more
doaj +2 more sources
Deciphering the Contribution of TATA Box and 5′UTR to Defense Signaling in Rice Under Blast Infection [PDF]
BiologyThe TATA box and 5′untranslated region (5′UTR) are critical regulatory elements that influence gene expression in plant defense responses. In rice (Oryza sativa), these elements modulate transcriptional and translational regulation during infection by ...
Xiaoru Fan +3 more
doaj +2 more sources
Molecular Cloning of a cDNA Encoding for Taenia solium TATA-Box Binding Protein 1 (TsTBP1) and Study of Its Interactions with the TATA-Box of Actin 5 and Typical 2-Cys Peroxiredoxin Genes. [PDF]
PLoS ONE, 2015 TATA-box binding protein (TBP) is an essential regulatory transcription factor for the TATA-box and TATA-box-less gene promoters. We report the cloning and characterization of a full-length cDNA that encodes a Taenia solium TATA-box binding protein 1 ...
Oscar Rodríguez-Lima +5 more
doaj +2 more sources
Modeling the Function of TATA Box Binding Protein in Transcriptional Changes Induced by HIV-1 Tat in Innate Immune Cells and the Effect of Methamphetamine Exposure [PDF]
Frontiers in Immunology, 2019 Innate immune cells are targets of HIV-1 infection in the Central Nervous System (CNS), generating neurological deficits. Infected individuals with substance use disorders as co-morbidities, are more likely to have aggravated neurological disorders ...
Ryan Tjitro +8 more
doaj +2 more sources
Functional analysis of the molecular interactions of TATA box-containing genes and essential genes. [PDF]
PLoS ONE, 2015 Genes can be divided into TATA-containing genes and TATA-less genes according to the presence of TATA box elements at promoter regions. TATA-containing genes tend to be stress-responsive, whereas many TATA-less genes are known to be related to cell ...
Sang-Hun Bae, Hyun Wook Han, Jisook Moon
doaj +2 more sources
Thinking outside the TATA box. [PDF]
EMBO Rep, 2014 When I was doing my PhD research, in the middle of the last century, the nature and complexity of the RNA transcripts of the genome was a topic of lively debate, into which my own work became drawn. The complexity of the mRNA population in a given tissue, cell‐type or developmental stage—considered as transcripts that were polyadenylated and associated
Jacobs H.
europepmc +4 more sources
MiRNAs regulate oxidative stress related genes via binding to the 3′ UTR and TATA-box regions: a new hypothesis for cataract pathogenesis [PDF]
BMC Ophthalmology, 2017 Background Age-related cataracts are related to oxidative stress. However, the genome-wide screening of cataract related oxidative stress related genes are not thoroughly investigated. Our study aims to identify cataract regulated miRNA target genes that
Changrui Wu +7 more
doaj +2 more sources