Results 11 to 20 of about 45,863 (244)
Comprehensive study in the inhibitory effect of berberine on gene transcription, including TATA box. [PDF]
PLoS ONE, 2011 Berberine (BBR) is an established natural DNA intercalator with numerous pharmacological functions. However, currently there are neither detailed reports concerning the distribution of this alkaloid in living cells nor reports concerning the relationship
Yugang Wang +6 more
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A conserved GA element in TATA-less RNA polymerase II promoters. [PDF]
PLoS ONE, 2011 Initiation of RNA polymerase (Pol) II transcription requires assembly of the pre-initiation complex (PIC) at the promoter. In the classical view, PIC assembly starts with binding of the TATA box-binding protein (TBP) to the TATA box.
Martin Seizl +6 more
doaj +3 more sources
, 2019 In this chapter we present very briefly the main framework used to establish the TATA-BOX project and the general methodology developed to codesign the territorial agroecological transition.
Bergez, Jacques-Eric, Therond, Olivier
openaire +3 more sources
Core promoter-specific gene regulation: TATA box selectivity and Initiator-dependent bi-directionality of serum response factor-activated transcription [PDF]
Biochimica Et Biophysica Acta - Gene Regulatory Mechanisms, 2016 Gene-specific activation by enhancers involves their communication with the basal RNA polymerase II transcription machinery at the core promoter.
Muyu Xu, Ernest Martinez
exaly +4 more sources
Optimizations of siRNA design for the activation of gene transcription by targeting the TATA-box motif. [PDF]
PLoS ONE, 2014 Small interfering RNAs (siRNAs) are widely used to repress gene expression by targeting mRNAs. Some reports reveal that siRNAs can also activate or inhibit gene expression through targeting the gene promoters.
Miaomiao Fan +6 more
doaj +2 more sources
How Proteins Recognize the TATA Box
Journal of Molecular Biology, 1996 The crystal structure of a complex of human TATA-binding protein with TATA-sequence DNA has been solved, complementing earlier TBP/DNA analyses from Saccharomyces cerevisiae and Arabidopsis thaliana. Special insight into TATA box specificity is provided by considering the TBP/DNA complex, not as a protein molecule with bound DNA, but as a DNA duplex ...
Igor Baikalov +2 more
exaly +3 more sources
BMC Genomics, 2010 Background The TATA-box and TATA-variants are regulatory elements involved in the formation of a transcription initiation complex. Both have been conserved throughout evolution in a restricted region close to the Transcription Start Site (TSS).
Lecharny Alain +2 more
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Evaluation of the Operationalisation of the TATA-BOX Process [PDF]
, 2019 AbstractThe chapter evaluates how the TATA-BOX process supported the collective design of an agroecological transition. In order to carry out this evaluation, we interviewed a panel of 24 participants about their experience of the process and their opinions on it.
Taverne, Marie +3 more
openaire +4 more sources
Evaluating the evolutionary relationship of TATA binding protein (TBP) with various folding patterns of protein domains using support vector machine (SVM) [PDF]
Scientific ReportsThis study focuses on the TATA-box binding, transcription initiation factor TFIID protein, (1tba) and employs a comprehensive approach combining structural, sequence and machine learning-based analysis to investigate its evolutionary relationships.
Muthu Krishnan Selvaraj, Jasmeet Kaur
doaj +2 more sources
Вавиловский журнал генетики и селекции, 2014 Interaction ofthe TATA-binding protein (ТВР) with the TATA box and formation ofthe TBP/TATA complex is the first step in the transcription complex assembly and the central event in transcription regulation.
I. A. Drachkova +8 more
doaj +1 more source