Results 31 to 40 of about 45,863 (244)

Investigating the sequence landscape in the Drosophila initiator core promoter element using an enhanced MARZ algorithm [PDF]

open access: yesPeerJ, 2023
The core promoter elements are important DNA sequences for the regulation of RNA polymerase II transcription in eukaryotic cells. Despite the broad evolutionary conservation of these elements, there is extensive variation in the nucleotide composition of
Jacqueline M. Dresch   +3 more
doaj   +2 more sources

A functional promoter from the archaeon Halobacterium salinarum is also transcriptionally active in E. coli

open access: yesBMC Microbiology, 2022
Background Archaea form a third domain of life that is distinct from Bacteria and Eukarya. So far, many scholars have elucidated considerable details about the typical promoter architectures of the three domains of life.
Jinye Liang   +4 more
doaj   +1 more source

Sometimes Hot, Sometimes Not: The Relations Between Selected Situational Vocational Interests and Situation Perception

open access: yesEuropean Journal of Personality, EarlyView., 2020
Abstract Vocational interests are traditionally conceived as stable preferences for different activities. However, recent theorizing suggests their intraindividual variability. This preregistered experience sampling study examined intraindividual variation in selected vocational interests states and related situation and person factors (N = 237 ...
Lena Roemer   +3 more
wiley   +1 more source

Activin A induces ovine follicle stimulating hormone beta using -169/-58 bp of its promoter and a simple TATA box

open access: yesReproductive Biology and Endocrinology, 2009
Background Activin A increases production of follicle stimulating hormone (FSH) by inducing transcription of its beta subunit (FSHB). This induction has been studied here in LbetaT2 gonadotropes using transient expression of ovine FSHBLuc (-4741 bp of ...
Miller William L, Han Sang-oh
doaj   +1 more source

Human_SNP_TATAdb: a database of SNPs that statistically significantly change the affinity of the TATA-binding protein to human gene promoters: genome-wide analysis and use cases

open access: yesВавиловский журнал генетики и селекции, 2023
It was previously shown that the expression levels of human genes positively correlate with TBP affinity for the promoters of these genes. In turn, single nucleotide polymorphisms (SNPs) in human gene promoters can affect TBP affinity for DNA and, as a ...
S. V. Filonov   +7 more
doaj   +1 more source

AN EXPERIMENTAL STUDY OF THE EFFECT OF RARE POLYMORPHISMS OF HUMAN HBB, HBD AND F9 PROMOTER TATA BOXES ON THE KINETICS OF INTERACTION WITH THE TATA-BINDING PROTEIN

open access: yesВавиловский журнал генетики и селекции, 2018
Human genes HBB, HBD and F9 belong to the hematopoiesis system. The deficiency or excess of these genes’ products is the cause of hereditary thalassemias of various severity and haemophilia B Leyden.
E. B. Sharypova   +7 more
doaj   +1 more source

Conformational impact on deformation of DNA TATA-box

open access: yes, 2020
The theoretical study of deformability of special sequence of DNA double helix TATA-box is presentated. The paper elaborates on the mechanisms of abnormal deformation of DNA TATA-box double helix that cannot be explained using the standard mechanical ...
Volkov, S. N., Kanevska, P. P.
core   +1 more source

Links between core promoter and basic gene features influence gene expression

open access: yesBMC Genomics, 2008
Background Diversity in rates of gene expression is essential for basic cell functions and is controlled by a variety of intricate mechanisms.
Sinvani Hadar   +4 more
doaj   +1 more source

Sites of RNA polymerase III transcription initiation and Ty3 integration at the U6 gene are positioned by the TATA box. [PDF]

open access: yes, 1993
The function of a TATA element in RNA polymerase (EC 2.7.7.6) III transcription of a naturally TATA-containing U6 snRNA gene and a naturally TATA-less tRNA gene was probed by transcription and Ty3 transposition analyses.
Chalker, DL, Sandmeyer, SB
core   +1 more source

A Composite Polyadenylation Signal with TATA Box Function [PDF]

open access: yesMolecular and Cellular Biology, 2000
A variant polyadenylation signal, which is conserved and employed by mammalian hepadnaviruses, has a sequence resembling that of the TATA box. We report here that this composite box manifests all the promoter characteristics. It binds effectively TATA-binding protein with TFIIB and TFIIA in a synergistic manner. This capacity, however, is lost when the
N, Paran, A, Ori, I, Haviv, Y, Shaul
openaire   +2 more sources

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