Study on Interaction Between TATA-Box Binding Protein (TBP), TATA-Box and Multiprotein Bridging Factor 1(MBF1) in Beauveria bassiana by Graphene-Based Electrochemical Biosensors [PDF]
Frontiers in Chemistry, 2020 The regulation of transcription level is an important step in gene expression process. Beauveria bassiana is a broad-spectrum insecticidal fungi widely used in the biologic control of arthropod.
Chi Song +7 more
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Modeling the Function of TATA Box Binding Protein in Transcriptional Changes Induced by HIV-1 Tat in Innate Immune Cells and the Effect of Methamphetamine Exposure [PDF]
Frontiers in Immunology, 2019 Innate immune cells are targets of HIV-1 infection in the Central Nervous System (CNS), generating neurological deficits. Infected individuals with substance use disorders as co-morbidities, are more likely to have aggravated neurological disorders ...
Ryan Tjitro +8 more
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On the Role of TATA Boxes and TATA-Binding Protein in Arabidopsis thaliana
Plants, 2023 For transcription initiation by RNA polymerase II (Pol II), all eukaryotes require assembly of basal transcription machinery on the core promoter, a region located approximately in the locus spanning a transcription start site (−50; +50 bp). Although Pol
L. K. Savinkova +2 more
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TATA box-binding protein-related factor 3 drives the mesendoderm specification of human embryonic stem cells by globally interacting with the TATA box of key mesendodermal genes [PDF]
Stem Cell Research & Therapy, 2020 Background Mesendodermal formation during early gastrulation requires the expression of lineage-specific genes, while the regulatory mechanisms during this process have not yet been fully illustrated.
He Liang +4 more
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Molecular Cloning of a cDNA Encoding for Taenia solium TATA-Box Binding Protein 1 (TsTBP1) and Study of Its Interactions with the TATA-Box of Actin 5 and Typical 2-Cys Peroxiredoxin Genes. [PDF]
PLoS ONE, 2015 TATA-box binding protein (TBP) is an essential regulatory transcription factor for the TATA-box and TATA-box-less gene promoters. We report the cloning and characterization of a full-length cDNA that encodes a Taenia solium TATA-box binding protein 1 ...
Oscar Rodríguez-Lima +5 more
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Evaluating the evolutionary relationship of TATA binding protein (TBP) with various folding patterns of protein domains using support vector machine (SVM) [PDF]
Scientific ReportsThis study focuses on the TATA-box binding, transcription initiation factor TFIID protein, (1tba) and employs a comprehensive approach combining structural, sequence and machine learning-based analysis to investigate its evolutionary relationships.
Muthu Krishnan Selvaraj, Jasmeet Kaur
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Nuclear respiratory factor 1 mediates the transcription initiation of insulin-degrading enzyme in a TATA box-binding protein-independent manner. [PDF]
PLoS ONE, 2012 CpG island promoters often lack canonical core promoter elements such as the TATA box, and have dispersed transcription initiation sites. Despite the prevalence of CpG islands associated with mammalian genes, the mechanism of transcription initiation ...
Lang Zhang, Qingyang Ding, Zhao Wang
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microRNA dysregulation in polyglutamine toxicity of TATA-box binding protein is mediated through STAT1 in mouse neuronal cells [PDF]
Journal of Neuroinflammation, 2017 Background Polyglutamine diseases constitute a class of neurodegenerative disorders associated with expansion of the cytosine-adenine-guanine (CAG) triplet, in protein coding genes.
Reema Roshan +5 more
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DR5 Governs Compound Exocytosis in Colonic Goblet Cells via TATA‐Box Binding Protein‐Dependent Bestrophin‐2 Transcriptional Regulation [PDF]
Advanced ScienceThe colonic mucus barrier, dependent on goblet cell‐secreted mucin2 (Muc2), prevents microbial invasion. Compound exocytosis enables the rapid, high‐volume release of mucus from goblet cells; its underlying mechanisms, however, remain unclear.
Ying Wang +9 more
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Methionine Synthase Interacts With the Methionine Adenosyl-Transferase MATα2 and the DNA Methyltransferase DNMT3b in the Nucleus. [PDF]
J Inherit Metab DisThis study shows that methionine synthase (MS) interacts with MATα2, responsible for SAM production, and the methyltransferase DNMT3b in the nucleus. These results support the idea that spatial compartmentalization of one‐carbon metabolism could play a major role in regulating the epigenome.
Jeandel M +8 more
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