Results 31 to 40 of about 49,724 (234)

c-Fos-Induced Activation of a TATA-Box-Containing Promoter Involves Direct Contact with TATA-Box-Binding Protein [PDF]

Molecular and Cellular Biology, 1994
Transcriptional activation in eukaryotes involves protein-protein interactions between regulatory transcription factors and components of the basal transcription machinery. Here we show that c-Fos, but not a related protein, Fra-1, can bind the TATA-box-binding protein (TBP) both in vitro and in vivo and that c-Fos can also interact with the ...
R, Metz, A J, Bannister, J A, Sutherland, C, Hagemeier, E C, O'Rourke, A, Cook, R, Bravo, T, Kouzarides   +7 more
openaire   +2 more sources

TC-motifs at the TATA-box expected position in plant genes: a novel class of motifs involved in the transcription regulation

BMC Genomics, 2010
Background The TATA-box and TATA-variants are regulatory elements involved in the formation of a transcription initiation complex. Both have been conserved throughout evolution in a restricted region close to the Transcription Start Site (TSS).
Lecharny Alain, Brunaud Véronique, Bernard Virginie   +2 more
doaj   +1 more source

DNA Topoisomerases Are Required for Preinitiation Complex Assembly during GAL Gene Activation. [PDF]

PLoS ONE, 2015
To investigate the importance of topoisomerases for transcription of the galactose induced genes, we have studied the expression of GAL1, GAL2, GAL7 and GAL10 in Saccharomyces cerevisiae cells deficient for topoisomerases I and II.
Morten Roedgaard, Jacob Fredsoe, Jakob Madsen Pedersen, Lotte Bjergbaek, Anni Hangaard Andersen   +4 more
doaj   +1 more source

STIL binding to Polo-box 3 of PLK4 regulates centriole duplication [PDF]

, 2015
Polo-like kinases (PLK) are eukaryotic regulators of cell cycle progression, mitosis and cytokinesis; PLK4 is a master regulator of centriole duplication.
Timm Maier, Gabryjonczyk, Anna-Maria, Hiller, Sebastian, Imseng, Stefan, Böhm, Raphael, Maier, Timm, Christian Arquint, Raphael Böhm, Sebastian Hiller, Anna-Maria Gabryjonczyk, Arquint, Christian, Stefan Imseng, Nigg, Erich A., Evelyn Sauer, Erich A Nigg, Sauer, Evelyn   +15 more
core   +1 more source

Snf2 family ATPases and DExx box helicases:differences and unifying concepts from high-resolution crystal structures [PDF]

, 2006
Proteins with sequence similarity to the yeast Snf2 protein form a large family of ATPases that act to alter the structure of a diverse range of DNA-protein structures including chromatin. Snf2 family enzymes are related in sequence to DExx box helicases,
Owen-Hughes, Tom; id_orcid, Flaus, Andrew, Hopfner, Karl-Peter, Dürr, Harald   +3 more
core   +1 more source

CTGC motifs within the HIV core promoter specify Tat-responsive pre-initiation complexes

Retrovirology, 2012
Background HIV latency is an obstacle for the eradication of HIV from infected individuals. Stable post-integration latency is controlled principally at the level of transcription.
Wilhelm Emmanuelle, Doyle Marie-Christine, Nzaramba Isaac, Magdzinski Alexandre, Dumais Nancy, Bell Brendan   +5 more
doaj   +1 more source

Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control [PDF]

, 2014
In vitro, assembly of box C/D small nucleolar ribonucleoproteins (snoRNPs) involves the sequential recruitment of core proteins to snoRNAs. In vivo, however, assembly factors are required (NUFIP, BCD1, and the HSP90–R2TP complex), and it is unknown ...
Franck Vandermoere, Ahmad, Yasmeen, Bertrand, Edouard, Bérengère Pradet-Balade, Leonhardt, Heinrich, Charron, Christophe, Hallais, Marie, Christophe Charron, Marie Hallais, Vandermoere, Franck, Jonathan Bizarro, Pradet-Balade, Berengere, Christiane Branlant, Yasmeen Ahmad, Chagot, Marie-Eve, Céline Verheggen, Lamond, Angus; id_orcid, Heinrich Leonhardt, Branlant, Christiane, Edouard Bertrand, Lamond, Angus, Charpentier, Bruno, Angus Lamond, Xavier Manival, Manival, Xavier, Marie-Eve Chagot, Westman, Belinda, Boulon, Severine, Belinda Westman, Séverine Boulon, Verheggen, Celine, Bruno Charpentier, Bizarro, Jonathan   +32 more
core   +1 more source

The Entamoeba histolytica TBP and TRF1 transcription factors are GAAC-box binding proteins, which display differential gene expression under different stress stimuli and during the interaction with mammalian cells

Parasites & Vectors, 2018
Background Entamoeba histolytica is the protozoan parasite responsible for human amebiasis. It causes up to 100,000 deaths worldwide each year. This parasite has two closely related basal transcription factors, the TATA-box binding protein (EhTBP) and ...
Ravi Kumar Narayanasamy, Carlos Alberto Castañón-Sanchez, Juan Pedro Luna-Arias, Guillermina García-Rivera, Bartolo Avendaño-Borromeo, María Luisa Labra-Barrios, Jesús Valdés, María Esther Herrera-Aguirre, Esther Orozco   +8 more
doaj   +1 more source

Conformation of the Mineralocorticoid Receptor N-terminal Domain: Evidence for Induced and Stable Structure [PDF]

, 2010
The mineralocorticoid receptor (MR) binds the steroid hormones aldosterone and cortisol and has an important physiological role in the control of salt homeostasis.
Fischer, Katharina, Watt, Carolyn, McEwan, Iain Joseph, Nicholas C. Price, Kelly, S.M., Katharina Fischer, Price, N.C., McEwan, I. J., Watt, K., Fischer, K., Price, Nicholas C., Sharon M. Kelly, Kate Watt, Iain J. McEwan, Kelly, Sharon M.   +14 more
core   +1 more source

Ultrastructural characterisation of Bacillus subtilis TatA complexes suggests they are too small to form homooligomeric translocation pores [PDF]

, 2013
Tat-dependent protein transport permits the traffic of fully folded proteins across membranes in bacteria and chloroplasts. The mechanism by which this occurs is not understood.
Monteferrante, Carmine G., Robinson, Colin, Baglieri, Jacopo, Beck, Daniel, Vasisht, Nishi, Smith, Corinne J., Baglieri, J., van Dijl, Jan Maarten, Dijl, Jan Maarten van   +8 more
core   +1 more source