Results 211 to 220 of about 45,863 (244)

TFIID binds in the minor groove of the TATA box

Cell, 1991
We have analyzed the interaction of the general RNA polymerase II transcription factor TFIID with its DNA-binding site, the TATA box (consensus sequence TATAAAA). We have demonstrated that TFIID, unlike most sequence-specific DNA-binding proteins, interacts primarily within the minor groove of the DNA helix.
D B, Starr, D K, Hawley
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SNPS IN THE HIV-1 TATA BOX AND THE AIDS PANDEMIC

Journal of Bioinformatics and Computational Biology, 2010
Evolutionary trends have been examined in 146 HIV-1 forms (2662 copies, 2311 isolates) polymorphic for the TATA box using the "DNA sequence→affinity for TBP" regression (TBP is the TATA binding protein). As a result, a statistically significant excess of low-affinity TATA box HIV-1 variants corresponding to a low level of both basal and TAT-dependent ...
Valentin V. Suslov, Petr M. Ponomarenko, Vadim M. Efimov, Ludmila K. Savinkova, Mikhail P. Ponomarenko, Nikolay A. Kolchanov   +5 more
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On Discriminating a TATA-box from putative TATA boxes: A Case Study Using Plant Genome

2005 IEEE Computational Systems Bioinformatics Conference - Workshops (CSBW'05), 2006
Prediction of a promoter is one of the many active areas of bioinformatics. The outcome of a promoter detection algorithm is directly or indirectly influenced by the success of identifying the location of a TATA box in a promoter sequence. A profiling technique is very often used to find putative TATA boxes, but discriminating a TATA box from putative ...
openaire   +1 more source

RNAa Induced by TATA Box-Targeting MicroRNAs

2017
Recent studies reveal that some nuclear microRNAs (miRNA) and synthesized siRNAs target gene promoters to activate gene transcription (RNAa). Interestingly, our group identified a novel HIV-1-encoded miRNA, miR-H3, which targets specifically the core promoter TATA box of HIV-1 and activates viral gene expression.
Yijun, Zhang, Hui, Zhang
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Gal4-VP16 and Gal4-AH Increase the Orientational and Axial Specificity of TATA Box Recognition by TATA Box Binding Protein

Biochemistry, 2002
Previous work has shown that binding of the TATA box binding protein (TBP) to the TATA box is a rate-limiting step during pre-initiation complex (PIC) formation. Although the transcription of eukaryotic genes normally proceeds in one direction, studies in solution have shown that TBP lacks the information necessary to orient itself on the TATA box ...
Alexis R, Kays, Alanna, Schepartz
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[Prognosis of affinity change of the TATA-binding protein to TATA-boxes upon polymorphisms of the human gene promoter TATA boxes].

Molekuliarnaia biologiia, 2009
TATA-binding protein (TBP) is a subunit of basal transcription factor TFIID that recognizes and binds to the TATA-box on TATA-containing promoters of class II genes, and starts assembling RNA polymerase II basal transcription complex. It is shown in many works that the sequence of TATA-box with its flanking regions affects the level of basal and ...
P M, Ponomarenko, M P, Ponomarenko, I A, Drachkova, M V, Lysova, T V, Arshinova, L K, Savinkova, N A, Kolchanov   +6 more
openaire   +1 more source

TATA Box

2008
  +4 more sources

Signals for TBP/TATA box recognition.

Journal of molecular biology, 2000
The TATA box-binding protein (TBP) recognizes its target sites (TATA boxes) by indirectly reading the DNA sequence through its conformation effects (indirect readout). Here, we explore the molecular mechanisms underlying indirect readout of TATA boxes by TBP by studying the binding of TBP to adenovirus major late promoter (AdMLP) sequence variants ...
A, Bareket-Samish, I, Cohen, T E, Haran
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TATA Box

2006
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TATA Box

2001
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