Results 121 to 130 of about 1,190 (173)
Muscle &Nerve, Volume 74, Issue 2, Page 496-499, August 2026.
Hiroyasu Inoue +7 more
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Commentary: LRP1 Is a Master Regulator of Tau Uptake and Spread
Frontiers in Neurology, 2020 Conor Fearon +3 more
doaj +1 more source
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2001 S, Kosaka, H, Takuma, H, Mori
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Cellular and Molecular Life Sciences, 2007
Tau is a microtubule-associated protein predominantly expressed in nerve cells that promote microtubule assembly and microtubule stabilization. Tau is a cytosolic protein mainly present in axons and involved in anterograde axonal transport. In several neurodegenerative diseases, as for example Alzheimer's disease, tau metabolism is altered.
Hernández, Félix, Ávila, Jesús
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Tau is a microtubule-associated protein predominantly expressed in nerve cells that promote microtubule assembly and microtubule stabilization. Tau is a cytosolic protein mainly present in axons and involved in anterograde axonal transport. In several neurodegenerative diseases, as for example Alzheimer's disease, tau metabolism is altered.
Hernández, Félix, Ávila, Jesús
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Annual Review of Neuroscience, 2001
▪ Abstract The defining neuropathological characteristics of Alzheimer's disease are abundant filamentous tau lesions and deposits of fibrillar amyloid β peptides. Prominent filamentous tau inclusions and brain degeneration in the absence of β-amyloid deposits are also hallmarks of neurodegenerative tauopathies exemplified by sporadic corticobasal ...
V M, Lee, M, Goedert, J Q, Trojanowski
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▪ Abstract The defining neuropathological characteristics of Alzheimer's disease are abundant filamentous tau lesions and deposits of fibrillar amyloid β peptides. Prominent filamentous tau inclusions and brain degeneration in the absence of β-amyloid deposits are also hallmarks of neurodegenerative tauopathies exemplified by sporadic corticobasal ...
V M, Lee, M, Goedert, J Q, Trojanowski
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2023
Tauopathies are a clinically and neuropathologically heterogeneous group of neurodegenerative disorders, characterized by abnormal tau aggregates. Tau, a microtubule-associated protein, is important for cytoskeletal structure and intracellular transport.
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Tauopathies are a clinically and neuropathologically heterogeneous group of neurodegenerative disorders, characterized by abnormal tau aggregates. Tau, a microtubule-associated protein, is important for cytoskeletal structure and intracellular transport.
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Current Opinion in Neurology, 2017
Purpose of review The purpose of this review is to provide an update on the role of tau beyond the stabilization of microtubules and on the clinical, pathological, diagnostic and therapeutic aspects of tauopathies. Recent findings Beyond its function as a microtubule-associated tau ...
Thibaud, Lebouvier +2 more
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Purpose of review The purpose of this review is to provide an update on the role of tau beyond the stabilization of microtubules and on the clinical, pathological, diagnostic and therapeutic aspects of tauopathies. Recent findings Beyond its function as a microtubule-associated tau ...
Thibaud, Lebouvier +2 more
openaire +2 more sources