Results 91 to 100 of about 327,793 (259)

Diterpene Synthases and Their Responsible Cyclic Natural Products [PDF]

open access: yes, 2014
This review provides an overview of diterpene synthases which were initially identified via genetic and/or biochemical means, traversing all organisms researched to ...
Hai-Yan Gong, Xiao-Ya Chen, Ying Zeng
core   +1 more source

Anti‐Cancer, Anti‐Inflammatory, and Analgesic Effects of Taxus wallichaina Extracts and Its Biosynthesized Silver Nanoparticles

open access: yesFood Science &Nutrition, Volume 13, Issue 11, November 2025.
Taxus wallichaina extracts and its biosynthesized silver nanoparticles shows promising anticancer and anti‐inflammatory properties. ABSTRACT This study investigates the green synthesis of silver nanoparticles (AgNPs) using Taxus wallichiana Zucc. and evaluates their pharmacological potential.
Fazli Hadi   +11 more
wiley   +1 more source

Interactions between co-habitating fungi elicit synthesis of Taxol from an endophytic fungus in host Taxus plants

open access: yesFrontiers in Microbiology, 2013
Within a plant, there can exist an ecosystem of pathogens and endophytes, the latter described as bacteria and fungal inhabitants that thrive without causing disease to the host.
Sameh S.M. Soliman, Manish N Raizada
doaj   +1 more source

Deep sequencing reveals transcriptome re-programming of Taxus × media cells to the elicitation with methyl jasmonate. [PDF]

open access: yesPLoS ONE, 2013
Plant cell culture represents an alternative source for producing high-value secondary metabolites including paclitaxel (Taxol®), which is mainly produced in Taxus and has been widely used in cancer chemotherapy.
Guiling Sun   +8 more
doaj   +1 more source

High efficiency protoplast isolation from in vitro cultures and hairy roots of Maesa lanceolata [PDF]

open access: yes, 2010
In vitro cultures of the medicinal plant Maesa lanceolata were established to enable the cultivation of plant material for the production of protoplasts.
Geelen, Danny, Lambert, Ellen
core   +1 more source

A large scale prediction of bacteriocin gene blocks suggests a wide functional spectrum for bacteriocins

open access: yes, 2015
Bacteriocins are peptide-derived molecules produced by bacteria, whose recently-discovered functions include virulence factors and signalling molecules as well as their better known roles as antibiotics.
Freed, Stefan D   +3 more
core   +1 more source

Development of a Human Preclinical Platform for the Identification of Neuroprotective Compounds

open access: yesEuropean Journal of Neuroscience, Volume 62, Issue 10, November 2025.
Neuroprotection screening on neurons and OLs in oxidative stress and axonal damage assays. Analysis of neurite outgrowth, apoptosis, ROS, OL differentiation and proteomics. Cuprizone model assessed effects on neurodegeneration, inflammation and pro‐myelination.
Raquel Guerrero González   +8 more
wiley   +1 more source

Cardiovascular Disease Meets Cancer: Exploring the Epidemiology in China and Homotherapy Targeting Intersectional Mechanisms

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang   +6 more
wiley   +1 more source

Artemisinin: From Chinese Herbal Medicine to Modern Chemotherapy [PDF]

open access: yes, 2019
Malaria is a disease that has blighted humankind since early times. The first antimalarial treatment available to Europeans was the dried bark of the cinchona tree from Peru. The main problem in its use was adulteration by other material.
Butler, Anthony
core   +1 more source

Fusidic Acid Reverses Chemoresistance in Breast Cancer via Targeting DDX6 to Downregulate GSK‐3β/β‐Catenin Signaling

open access: yesAdvanced Science, Volume 12, Issue 39, October 20, 2025.
FA directly binds to residue H378 of DDX6 and promotes its interaction with HSC70, leading to CMA degradation of DDX6, thereby impairing GSK‐3β/β‐catenin signaling, inhibiting ABC transporter proteins, and enhancing chemosensitivity. Abstract ABC transporter protein‐mediated drug efflux is a significant contributor to induced resistance in breast ...
Xiaxia Fan   +5 more
wiley   +1 more source

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