Results 111 to 120 of about 327,793 (259)
BMEMat, Volume 3, Issue 3, September 2025.This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan +12 more
wiley +1 more source
Semi-dwarfism and lodging tolerance in tef (Eragrostis tef) is linked to a mutation in the α-Tubulin 1 gene [PDF]
, 2017 The semi-dwarf and lodging-tolerant kegne mutant linked to defects in microtubule orientation has the potential to enhance the productivity of an African orphan crop tef (Eragrostis ...
Assefa, Kebebew +7 more
core
, 2016 Being a complex diterpenoid, the potent anticancer drug, Taxol, requires complicated steps for its biosynthesis. In the present article, recent advances on Taxol biosynthesis pathway are reviewed, including many recently reported genes that regulate ...
Guo, BH, Jin, HB, Kai, GY, Tang, KX
core +2 more sources
Gram‐Scale Access to (3,11)‐Cyclotaxanes—Synthesis of 1‐Hydroxytaxuspine C
Angewandte Chemie International Edition, Volume 64, Issue 35, August 25, 2025.Belonging to the family of complex taxanes, 1‐hydroxytaxuspine C is a densely functionalized natural product. The synthesis was realized via a semisynthetic approach, starting from commercially available 10‐deacetylbaccatin III. A late‐stage photocyclization was utilized to install the characteristic transannular bond of complex taxanes, transforming ...
Philipp Schoch +4 more
wiley +1 more source
Isolation of Taxol-producing endophytes fungi from Iranian yew (Taxus baccata L.) [PDF]
, 2010 زمینه و هدف: تاکسول یکی از مهمترین داروهای ضد سرطان و منبع اولیه تهیه آن گیاه سرخدار است و با توجه به محدود بودن تعداد این درختان جایگزینی روش های دیگر تولید به جای استخراج از پوست گیاه امری ضروری به نظر می رسد.
Ebrahimi, M. +4 more
core
Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis. [PDF]
, 2017 The heart switches its energy substrate from glucose to fatty acids at birth, and maternal hyperglycemia is associated with congenital heart disease. However, little is known about how blood glucose impacts heart formation.
Braas, Daniel +21 more
core +2 more sources
Mitochondrial mRNA transcripts predict overall survival, tumor recurrence and progression in serous ovarian cancer : companion diagnostics for cancer therapy [PDF]
, 2017 Here, we performed a systematic analysis to discover new biomarkers of overall survival and tumor progression in ovarian cancer patients. More specifically, we determined whether nuclear-encoded mitochondrial genes related to mitochondrial biogenesis and
Freyer +15 more
core +1 more source
A Review on Taxol Production through Biotechnological Approaches
Journal of Medicinal Plants, 2018 Taxol is a very important anticancer drug which was first isolated from Yew plant (Taxus spp.). However, Taxol supply by extraction from natural sources, has several limitations, and cannot meet current marketchr('39')s demands.
M Majidi, AR tarinejad
doaj
, 2010 Fungi are used in many industrial processes, such as the production of enzymes, vitamins, polysaccharides, polyhydric alcohols, pigments, lipids, and glycolipids.
Arnold L. Demain, José L. Adrio
core +2 more sources