Alliance Between Conifer Trees and Endophytic Fungi Against Insect Defoliators
ABSTRACT Fungal endophytes can alter plant resistance against herbivores by indirectly influencing plant secondary metabolism or through direct effects of their own metabolism. However, the role of fungal endophytes in conifer defences to insect herbivores remains largely unknown.
Aziz Ullah +6 more
wiley +1 more source
Identification, characterization and molecular adaptation of class I redox systems for the production of hydroxylated diterpenoids [PDF]
Background De novo production of multi-hydroxylated diterpenoids is challenging due to the lack of efficient redox systems. Results In this study a new reductase/ferredoxin system from Streptomyces afghaniensis (AfR·Afx) was identified, which allowed ...
Bernhard Loll +7 more
core +3 more sources
Mitochondrial mRNA transcripts predict overall survival, tumor recurrence and progression in serous ovarian cancer : companion diagnostics for cancer therapy [PDF]
Here, we performed a systematic analysis to discover new biomarkers of overall survival and tumor progression in ovarian cancer patients. More specifically, we determined whether nuclear-encoded mitochondrial genes related to mitochondrial biogenesis and
Freyer +15 more
core +1 more source
Optimizing the biosynthesis of oxygenated and acetylated Taxol precursors in Saccharomyces cerevisiae using advanced bioprocessing strategies [PDF]
Laura E. Walls +11 more
openalex +1 more source
Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis. [PDF]
The heart switches its energy substrate from glucose to fatty acids at birth, and maternal hyperglycemia is associated with congenital heart disease. However, little is known about how blood glucose impacts heart formation.
Braas, Daniel +21 more
core +2 more sources
A Review on Taxol Production through Biotechnological Approaches
Taxol is a very important anticancer drug which was first isolated from Yew plant (Taxus spp.). However, Taxol supply by extraction from natural sources, has several limitations, and cannot meet current marketchr('39')s demands.
M Majidi, AR tarinejad
doaj
Fungi are used in many industrial processes, such as the production of enzymes, vitamins, polysaccharides, polyhydric alcohols, pigments, lipids, and glycolipids.
Arnold L. Demain, José L. Adrio
core +2 more sources
Arabidopsis katanin binds microtubules using a multimeric microtubule-binding domain. [PDF]
Katanin is a heterodimeric protein that mediates ATP-dependent destabilization of microtubules in animal cells. In plants, the catalytic subunit of Arabidopsis thaliana katanin (AtKSS, Arabidopsis thaliana Katanin Small Subunit) has been identified and ...
Conway, James +5 more
core +3 more sources
Isolation of Taxol-producing endophytes fungi from Iranian yew (Taxus baccata L.) [PDF]
زمینه و هدف: تاکسول یکی از مهمترین داروهای ضد سرطان و منبع اولیه تهیه آن گیاه سرخدار است و با توجه به محدود بودن تعداد این درختان جایگزینی روش های دیگر تولید به جای استخراج از پوست گیاه امری ضروری به نظر می رسد.
Ebrahimi, M. +4 more
core
Experimental design-aided systematic pathway optimization of glucose uptake and deoxyxylulose phosphate pathway for improved amorphadiene production [PDF]
Artemisinin is a potent antimalarial drug; however, it suffers from unstable and insufficient supply from plant source. Here, we established a novel multivariate-modular approach based on experimental design for systematic pathway optimization that ...
Chen, Xixian +4 more
core +1 more source

