Results 171 to 180 of about 2,363,919 (190)

Antagonism of Taxol Cytotoxicity by Prolactin: Implication for Patient Resistance to Chemotherapy

2007
Abstract : The objective of this investigation is to examine the protective effects of prolactin (PRL) against anti-cancer drugs. Three specific aims were formulated: 1) To characterize the protective effects of PRL against several anticancer drugs, 2) To determine anti-apoptotic mechanism(s), and 3) To examine the protective effects of PRL in vivo ...
openaire   +1 more source

Taxol: Mechanisms of Action and Resistancea

Annals of the New York Academy of Sciences, 1986
S B, Horwitz, L, Lothstein, J J, Manfredi, W, Mellado, J, Parness, S N, Roy, P B, Schiff, L, Sorbara, R, Zeheb   +8 more
openaire   +2 more sources

Antibiotic Resistance in the Patient With Cancer: Escalating Challenges and Paths Forward

Ca-A Cancer Journal for Clinicians, 2021
Amila K Nanayakkara, David E Greenberg, Vance Fowler   +2 more
exaly  

7 The biochemical pharmacology of taxol® and mechanisms of resistance

1995
Publisher Summary This chapter describes biochemical pharmacology of Taxol ® and its mechanisms of resistance. Microtubules, like DNA and RNA, are conserved structures in all eukaryotic cells with numerous and diverse functions. By forming a scaffolding network within cells, microtubules maintain cell shape.
openaire   +1 more source

Inhibition of STAT3 Reverses Taxol-Resistance in Ovarian Cancer by Down-Regulating G6PD Expression in Vitro

Biochemical and Biophysical Research Communications, 2022
Xiugui Sheng, Peng Zhang, Hao Sheng
exaly  

Differential expression of mRNAs in a taxol-resistant ovarian cancer cell line grown in the presence of taxol

Journal of the Society for Gynecologic Investigation, 1998
L GREGOIRE, A MUNKARAH, R MORRIS, Y MIN, W LANCASTER   +4 more
openaire   +1 more source

Acquisition of Taxol Resistance via P-Glycoprotein- and Non-P-Glycoprotein-Mediated Mechanisms in Human Ovarian Carcinoma Cells

Biochemical Pharmacology, 1997
Henry Simpkins, H Parekh, Hemant Parekh
exaly  

Identification of a Novel Function of TWIST, a bHLH Protein, in the Development of Acquired Taxol Resistance in Human Cancer Cells

Oncogene, 2004
Xin-Yuan Guan, Sai Wah Tsao, Hiu Wing Cheung   +2 more
exaly  

Inhibition of α Folate Receptor Resulting in a Reversal of Taxol Resistance in Nasopharyngeal Carcinoma

Otolaryngology - Head and Neck Surgery, 2012
Guolin Tan, Heqing Li, Yanhong Ma
exaly  

Op18/Stathmin Is Involved in the Resistance of Taxol Among Different Epithelial Carcinoma Cell Lines

Cancer Biotherapy and Radiopharmaceuticals, 2014
Xuechi Lin
exaly