Results 151 to 160 of about 22,844 (235)
ABSTRACT Introduction Avelumab is recommended as maintenance therapy for advanced urothelial carcinoma after platinum chemotherapy; however, immune‐related adverse events can be severe and refractory. Case Presentation A 79‐year‐old male developed immune‐related hepatitis during avelumab maintenance therapy following gemcitabine plus carboplatin for ...
Yuka Iwama +9 more
wiley +1 more source
Erratum: Downregulation of MicroRNA-455-3p Links to Proliferation and Drug Resistance of Pancreatic Cancer Cells via Targeting TAZ. [PDF]
Zhan T +6 more
europepmc +1 more source
ABSTRACT Ischaemic cardiovascular diseases, particularly myocardial infarction (MI), remain the leading causes of morbidity and mortality worldwide. Targeting extracellular vesicles (EVs) from the gut microbiota by diet may provide opportunities to improve cardiovascular health. Barley leaf (BL) has a long history of use in Traditional Chinese medicine
Wenjing Chen +10 more
wiley +1 more source
Protein Lactylation in Cancer: Mechanisms and Therapeutic Targets
This schematic illustrates the central role of lactylation, a lactate‐derived posttranslational modification, in linking metabolic reprogramming to cancer progression and therapy resistance. At its core, lactylation modulates proteins, influenced by metabolic shifts and environmental factors.
Qianying Ouyang +10 more
wiley +1 more source
Intra‐tumour heterogeneity is present in gastrointestinal tumours at the single‐cell level. Cell cycling, EMT, MYC and TNF‐α are the four main consensus meta‐programs in gastrointestinal tumours. Then, a prognostic model based on intratumoral heterogeneity was constructed using an artificial intelligence‐derived prognostic index.
Zhizhan Ni +12 more
wiley +1 more source
Critical threshold target attainment rates for tazobactam combined with piperacillin among patients admitted to the ICU with hospital-acquired pneumonia. [PDF]
Williamson R +18 more
europepmc +1 more source

