Results 131 to 140 of about 28,043 (224)

Obstructive Sleep Apnea: Epidemiology, Pathophysiology, Complications, Diagnosis, Management, and Emerging Fibrosis‐Linked Remodeling

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Obstructive sleep apnea (OSA) is characterized by recurrent upper‐airway collapse, which generates key nocturnal stressors including intermittent hypoxia, sleep fragmentation, intrathoracic pressure stress, and sympathetic activation. These physiological disturbances converge on shared biological mechanisms, including oxidative stress, inflammation ...
Nhi Ho Thi Thuy   +8 more
wiley   +1 more source

AEROBIC EXERCISE ATTENUATES HEPATIC LIPID PEROXIDATION IN AN EXPERIMENTAL MODEL OF OBESITY-ASSOCIATED NAFLD. [PDF]

open access: yesArq Gastroenterol
Lima MLRP   +6 more
europepmc   +1 more source

Biofluid Biomarkers of Cognitive Functioning in Bipolar Disorder: A Systematic Review by the Targeting Cognition and Older‐Age Bipolar Disorder ISBD Task Forces

open access: yesBipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Background Cognitive impairment is common in bipolar disorder (BD), but the underlying pathophysiology remains unclear. This systematic review aimed to (1) summarize all literature describing relationships of biofluid biomarkers and cognition in BD and (2) identify which biofluid biomarkers correlate most consistently with cognition in BD ...
Alexandra J. M. Beunders   +21 more
wiley   +1 more source

Role of human RNase 7 in neuronal and glial cell models: moving towards an unexpected new functional link

open access: yesThe FEBS Journal, Volume 293, Issue 15, Page 4660-4679, August 2026.
Human RNase 7 is known to exert antimicrobial activity in epithelial tissues. Here, using SH‐SY5Y and U‐87 MG, neuroblastoma and glioblastoma cell lines, respectively, we found that RNase 7 enhances immune responses to LPS stimulation by reducing the expression of pro‐inflammatory cytokines, nitric oxide, and ROS.
Rosanna Culurciello   +9 more
wiley   +1 more source

Effects of the herbicide 2,4 D active ingredient and commercial formulations on the early life stages of the amphibian Physalaemus gracilis. [PDF]

open access: yesEcotoxicology
Bridi C   +8 more
europepmc   +1 more source

Aerobic Endurance Training Modulates Cardiac Renin‐Angiotensin System Peptides and Matrix Metalloproteinase Activity During Chronic Stress

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT To investigate the involvement of metalloproteinases (MMPs) in the context of endurance training and their interactions with renin‐angiotensin signalling (RAS) in stress‐induced pathophysiological responses. Trained rats were submitted to 8‐weeks of endurance treadmill training with chronic mild stress (CMS), TS rats, and without CMS (T).
Vinicius Guzzoni   +14 more
wiley   +1 more source

Therapeutic intervention with sinomenine and irisin to preserve cardiac function after ischaemia–reperfusion injury

open access: yesExperimental Physiology, Volume 111, Issue 8, Page 3557-3569, 1 August 2026.
Abstract Despite advancements in reperfusion therapy, myocardial ischaemia–reperfusion (IR) injury remains a major clinical challenge. This study investigated whether a novel dual‐target pre‐conditioning strategy using sinomenine and irisin could enhance myocardial resistance against IR injury. Ninety male Sprague–Dawley rats were utilized.
Lianjun Wu   +3 more
wiley   +1 more source

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