Results 1 to 10 of about 184,470 (334)

Expression of FOXO1 in Liver Cancer and Its Prognostic Significance: An Analysis Based on TCGA

Zhongliu Fangzhi Yanjiu, 2021
Objective To investigate the expression and prognostic value of FOXO1 gene in liver cancer tissues based on TCGA and HPA databases. Methods The RNA-seq data of FOXO1 gene in liver cancer were downloaded from TCGA.
YANG Tingfang, WANG Li, ZHANG Yong
doaj   +1 more source

Integrated transcriptome analysis identifies APPL1/RPS6KB2/GALK1 as immune-related metastasis factors in breast cancer

Open Medicine, 2023
The aim of this study is to investigate the prognostic immune-related factors in breast cancer (BC) metastasis. The gene expression chip GSE159956 was downloaded from the gene expression omnibus database.
Chen Gang, Zhang Kun, Liang Zhi, Zhang Song, Dai Yuanping, Cong Yizi, Qiao Guangdong   +6 more
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A novel 10-gene immune-related lncRNA signature model for the prognosis of colorectal cancer

Mathematical Biosciences and Engineering, 2021
Background: The tumor immune microenvironment of colorectal cancer (CRC) affects tumor development, prognosis and immunotherapy strategies. Recently, immune-related lncRNA were shown to play vital roles in the tumor immune microenvironment.
Bin Ma, Lianqun Cao , Yongmin Li
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Construction and validation of a novel prognostic signature for uveal melanoma based on five metabolism-related genes

Mathematical Biosciences and Engineering, 2021
Background: Uveal melanoma (UM) is the most aggressive intraocular tumor worldwide. Accurate prognostic models are urgently needed. The present research aimed to construct and validate a prognostic signature is associated with overall survival (OS) for ...
Han Zhao , Yun Chen, Peijun Shen, Lan Gong   +3 more
doaj   +1 more source

High Levels of Class I Major Histocompatibility Complex mRNA Are Present in Epstein–Barr Virus-Associated Gastric Adenocarcinomas

Cells, 2020
Epstein−Barr virus (EBV) is responsible for approximately 9% of stomach adenocarcinomas. EBV-encoded microRNAs have been reported as reducing the function of the class I major histocompatibility complex (MHC-I) antigen presentation apparatus, which
Farhad Ghasemi, Steven F. Gameiro, Tanner M. Tessier, Allison H. Maciver, Joe S. Mymryk   +4 more
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The G Protein-Coupled Estrogen Receptor (GPER) Expression Correlates with Pro-Metastatic Pathways in ER-Negative Breast Cancer: A Bioinformatics Analysis

Cells, 2020
The G protein-coupled estrogen receptor (GPER, formerly known as GPR30) is a seven-transmembrane receptor that mediates estrogen signals in both normal and malignant cells.
Marianna Talia, Ernestina Marianna De Francesco, Damiano Cosimo Rigiracciolo, Maria Grazia Muoio, Lucia Muglia, Antonino Belfiore, Marcello Maggiolini, Andrew H. Sims, Rosamaria Lappano   +8 more
doaj   +1 more source

Identification of Gene-Environment Interactions by Non-Parametric Kendall’s Partial Correlation with Application to TCGA Ultrahigh-Dimensional Survival Genomic Data

Frontiers in Bioscience-Landmark, 2022
Background: In biomedical and epidemiological studies, gene-environment (G-E) interactions play an important role in the etiology and progression of many complex diseases.
Jie-Huei Wang, Chun-Ting Yang
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Single nucleotide polymorphism mutation related genes in bladder cancer for the treatment of patients: a study based on the TCGA database

Biotechnology & Biotechnological Equipment, 2021
Bladder cancer (BLCA) is a common malignancy and has a poor prognosis. Single nucleotide polymorphisms (SNPs) in genes are closely associated with the tumorigenesis and tumor development and yet are not well illustrated in BLCA.
Tengyun Long, Xiaoni Li, Guofei Zhang, Chunming Qiu, Ouyang Huan, Canbiao Sun, Yong Yang   +6 more
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Gene signature to predict prognostic survival of hepatocellular carcinoma

Open Medicine, 2022
Hepatocellular carcinoma (HCC) has a high incidence and poor prognosis and is the second most fatal cancer, and certain HCC patients also show high heterogeneity. This study developed a prognostic model for predicting clinical outcomes of HCC.
Li Li, Cao Yundi, Fan YingRui, Li Rong
doaj   +1 more source

Prognostic value of nicotinamide N-methyltransferase in human cancers: Evidence from a meta-analysis and database validation

Open Medicine, 2022
Previous studies indicated that dysregulated expression of nicotinamide N-methyltransferase (NNMT) contributed to the tumor progression and predicted poor prognosis in various cancers.
Dang Ling, Wang Yingdong
doaj   +1 more source