Results 31 to 40 of about 147,649 (246)

From TCGA to Treatment [PDF]

Cancer Discovery, 2012
Abstract A comprehensive molecular analysis of tumor samples from 825 patients with breast cancer, conducted through The Cancer Genome Atlas, suggests new approaches to therapy.
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Inflammation-Related Gene Signature for Predicting the Prognosis of Head and Neck Squamous Cell Carcinoma

International Journal of General Medicine, 2022
Yilong Lu,1 Zengrong Jia2 1School of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 2Thyroid Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of ...
Lu Y, Jia Z
doaj  

Prognostic Model Associated with Necroptosis in Colorectal Cancer based on Transcriptomic Analysis and Experimental Validation

Frontiers in Bioscience-Landmark
Purpose: Numerous studies have emphasised the importance of necroptosis in the malignant progression of colorectal cancer (CRC). However, whether necroptosis-related genes (NRGs) can be used to predict the prognosis of CRC remains to be revealed. Methods:
Yuying Huang, Licheng Li, Zhongmin Kang, Huali Luo, Xiaojing Lin, Shu Zhao, Qizhu Zhang, Qinshan Li, Honglin Liu, Mengxing Li   +9 more
doaj   +1 more source

Screening and Identification of Key Genes for Clinical Benefit of Immunotherapy on Lung Adenocarcinoma Based on TCGA Database

Zhongliu Fangzhi Yanjiu, 2020
Objective To identify key biomarkers for predicting the response to immunotherapy and elucidate the possible underlying mechanism in lung adenocarcinoma based on whole-genome sequencing.
QI Xiaoguang, QI Chunyan, QIN Boyu, HU Yi, HAN Weidong   +4 more
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LINC01572 is a Novel Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma

Frontiers in Bioscience-Landmark, 2023
Background: Lung adenocarcinoma (LUAD) is one of the most common and lethal cancer types worldwide. LINC0572 is a long non-coding RNA (lncRNA) that has been associated with the clinical characteristics of several types of malignancy.
Yaolin Zheng, Zhenshan Zhang, Xueyan Li, Leilei Wu, Xinliang Liu, Liang Liu, Jiayan Chen, Dongping Wei   +7 more
doaj   +1 more source

Molecular analysis of TCGA breast cancer histologic types

Cell Genomics, 2021
Breast cancer is classified into multiple distinct histologic types, and many of the rarer types have limited characterization. Here, we extend The Cancer Genome Atlas Breast Cancer (TCGA-BRCA) dataset with additional histologic type annotations in a total of 1,063 breast cancers.
Aatish Thennavan, Francisco Beca, Youli Xia, Susana Garcia-Recio, Kimberly Allison, Laura C. Collins, Gary M. Tse, Yunn-Yi Chen, Stuart J. Schnitt, Katherine A. Hoadley, Andrew Beck, Charles M. Perou   +11 more
openaire   +3 more sources

Racial disparities in hepatocellular carcinoma: a TCGA-based gene expression study of Caucasian and Asian populations [PDF]

Exploration of Targeted Anti-tumor Therapy
Aim: Hepatocellular carcinoma (HCC) displays both shared and ethnicity-specific molecular characteristics. Using transcriptomic data from The Cancer Genome Atlas (TCGA), we compared gene expression profiles between Asian and Caucasian HCC patients ...
Muhammad Rezki Rasyak, Sri Jayanti, Cyrollah Disoma, Bens Pardamean, Caecilia Sukowati   +4 more
doaj   +1 more source

Development and Validation of a Prognosis-Prediction Signature for Patients with Lung Adenocarcinoma Based on 11 Telomere-Related Genes

Frontiers in Bioscience-Landmark, 2023
Background: The occurrence and progression of lung cancer are correlated with telomeres and telomerase. Telomere length is reduced in the majority of tumors, including lung cancers.
Jia Liu, Sha Sha, Jian Wang, Xiaowei Gu, Menghua Du, Xu Lu   +5 more
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Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Fer-1 like family member 4 pseudogene

EXCLI Journal : Experimental and Clinical Sciences
Cutaneous melanoma is the deadliest form of skin cancer. Despite advancements in treatment, many patients still face poor outcomes. A deeper understanding of the mechanisms involved in melanoma pathogenesis is crucial for improving diagnosis and therapy.
Tomasz Kolenda, Kacper Guglas, Maciej Stasiak, Paulina Poter, Joanna Kozłowska-Masłoń, Piotr Białas, Joanna Sobocińska, Marlena Janiczek-Polewska, Patrycja Mantaj, Anna Paszkowska, Zefiryn Cybulski, Anna Teresiak, Urszula Kazimierczak, Anna Przybyła, Andrzej Mackiewicz, Jacek Mackiewicz   +15 more
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