Results 81 to 90 of about 184,470 (334)
International Journal of General Medicine, 2021 Xiaoyu Wang,* Weichun Tang,* Yilin Lu, Jun You, Yun Han, Yanli Zheng Department of Obstetrics and Gynecology, Nantong First People’s Hospital, Nantong, Jiangsu, 226001, People’s Republic of China*These authors contributed equally to this ...
Wang X +5 more
doaj
Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
Frontiers in Medicine, 2020 Background: Tumor microenvironment is essential for breast cancer progression and metastasis. Our study sets out to examine the genes affecting stromal and immune infiltration in breast cancer progression and prognosis.
Ming Xu +7 more
semanticscholar +1 more source
TCGA Molecular Subgroups in Endometrial Undifferentiated/Dedifferentiated Carcinoma
Pathology & Oncology Research, 2019 We aimed to classify undifferentiated/dedifferentiated carcinoma (UDC/DDC) according to the four TCGA molecular subgroups of endometrial cancer: microsatellite-instable/hypermutated (MSI), POLE-mutant/ultramutated (POLE), copy-number-low/p53-wild-type (p53wt), and copy-number-high/p53-abnormal (p53abn), through a systematic review and meta-analysis ...
Travaglino A. +6 more
openaire +6 more sources
Integrative network analysis of TCGA data for ovarian cancer [PDF]
BMC Systems Biology, 2014 Over the past years, tremendous efforts have been made to elucidate the molecular basis of the initiation and progression of ovarian cancer. However, most existing studies have been focused on individual genes or a single type of data, which may lack the power to detect the complex mechanisms of cancer formation by overlooking the interactions of ...
Joanna E. Burdette +2 more
openaire +2 more sources
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Prognostic value of tumour microenvironment‐related genes by TCGA database in rectal cancer
Journal of Cellular and Molecular Medicine, 2021 Rectal cancer is a common malignant tumour and the progression is highly affected by the tumour microenvironment (TME). This study intended to assess the relationship between TME and prognosis, and explore prognostic genes of rectal cancer.
Chao Li +4 more
semanticscholar +1 more source
All LifeThis study aims to improve breast cancer (BC) prognostic biomarker detection, overcoming current methods’ complexity, high – cost, and low – precision issues.
Shangyi Lu +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Fine-Tuning and training of densenet for histopathology image representation using TCGA diagnostic slides [PDF]
Medical Image Anal., 2021 Abtin Riasatian +21 more
semanticscholar +1 more source