Results 191 to 200 of about 330,850 (283)

ProTCR: a protein language model-driven framework for decoding TCR-antigen recognition toward precision immunotherapies. [PDF]

Brief Bioinform
Xu M, Lu M, Liu P, Zhang S, Chen L, Liu Q, Lin Y, Xie L.   +7 more
europepmc   +1 more source

Multiobjective Environmental Cleanup with Autonomous Surface Vehicle Fleets Using Multitask Multiagent Deep Reinforcement Learning

Advanced Intelligent Systems, EarlyView.
This study presents a multitask strategy for plastic cleanup with autonomous surface vehicles, combining exploration and cleaning phases. A two‐headed Deep Q‐Network shared by all agents is traineded via multiobjective reinforcement learning, producing a Pareto front of trade‐offs.
Dame Seck, Samuel Yanes, Manuel Perales, Daniel Gutiérrez, Sergio Toral   +4 more
wiley   +1 more source

Clonal CD8⁺ T cells populate the leptomeninges and coordinate with immune cells in human degenerative brain diseases. [PDF]

Nat Immunol
Hobson R, Levy SHS, Singal CMS, Flaherty D, Xiao H, Ciener B, Reddy H, Zabinyakov N, Kim CY, Teich AF, Shneider NA, Bradshaw EM, Elyaman W.   +12 more
europepmc   +1 more source

Pro‐Inflammatory c‐Met+ CD4 T Cells in Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Hepatocyte growth factor (HGF) binds exclusively the c‐Met surface receptor, and the HGF/c‐Met axis regulates T cell function in autoimmune diseases. We analyzed c‐Met expression on human CD4 T cells in the blood and cerebrospinal fluid (CSF) from patients with multiple sclerosis (MS) versus non‐inflammatory neurological disease (NIND), to ...
Gautier Breville, Mahdia Benkhoucha, Ayman Rezk, Ngoc Lan Tran, Isis Senoner, Amit Bar‐Or, Patrice H. Lalive   +6 more
wiley   +1 more source

Strenuous Exercise Alters Brain Creatine and Glutamate/Glutamine (Glx) in Humans: Evidence From Dynamic ¹H-MRS and ¹H-MRSI. [PDF]

FASEB J
Pratt J, Kaiser A, Henthorn L, Mundell O, From E, Kennerley AJ, Sale C.   +6 more
europepmc   +1 more source

Sustained hippocampal neuroinflammation and subsequent glutamatergic dysfunction in juvenile idiopathic arthritis: evidence from proton magnetic resonance spectroscopy (¹H-MRS). [PDF]

Arthritis Res Ther
Han H, Weng Y, Yang S, Han C, Yi C, Wu H, Xiao J.   +6 more
europepmc   +1 more source

Ventricular Asystole During Le Fort I Orthognathic Surgery: A Case Consistent with Trigeminocardiac Reflex and a Mini Review. [PDF]

Clin Pract
Ghosh S, Armanious S, Nair A, Ulku Z, Sultan D, Pellecchia R.   +5 more
europepmc   +1 more source

Design and Optimization of a Novel Kalina‐Organic Rankine Cycle System Based on LNG Cold Energy Utilization

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study proposes a novel integrated system (SDKC‐DORC) that combines a split‐flow dual‐pressure Kalina cycle with a secondary organic Rankine cycle for the synergistic utilization of solar energy and liquefied natural gas (LNG) cold energy.
Ke Xiao, Kun Wang, Wenquan Jiang, Fan Yang, Changshun Wang, Chengjie Su, Junjie Liu   +6 more
wiley   +1 more source

Circulating T-cell receptor repertoire and clinicopathological correlations in breast cancer patients: immune repertoire analysis from the VGH-TAYLOR study. [PDF]

Breast Cancer Res
Tseng LM, Huang CC, Chen JL, Tsai YF, Chao TC, Wu WC, Lien PJ, Lin YS, Feng CJ, Chen YJ, Lai JI, Chiu JH, Hsu CY, Liu CY.   +13 more
europepmc   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source