Results 81 to 90 of about 330,850 (283)
Why do some T cell receptor cytoplasmic domains associate with the plasma membrane?
Frontiers in Immunology, 2012 Based on studies in model systems it has been proposed that the cytoplasmic domains of T cell receptor signalling subunits that have polybasic motifs associate with the plasma membrane, and that this regulates their phosphorylation. Recent experiments in
Philip Anton evan der Merwe +2 more
doaj +1 more source
Anomalous $tq\gamma$ coupling effects in exclusive radiative B-meson decays
, 2011 The top-quark FCNC processes will be searched for at the CERN LHC, which are correlated with the B-meson decays. In this paper, we study the effects of top-quark anomalous interactions $tq\gamma$ in the exclusive radiative $B\to K^*\gamma$ and $B\to\rho ...
A Ali +72 more
core +1 more source
Advanced Materials, EarlyView.The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon +21 more
wiley +1 more source
The promise of adoptive cellular immunotherapies in hepatocellular carcinoma
OncoImmunology, 2020 Hepatocellular Carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide. Current systemic therapies result only in modest benefits and new therapeutic options are critically needed.
Peter G. Hendrickson +6 more
doaj +1 more source
Characterization of the T cell receptor repertoire causing collagen arthritis in mice [PDF]
, 1993 Collagen type II-induced arthritis (CIA) is generated in susceptible rodent strains by intradermal injections of homologous or heterologous native type II collagen in complete Freund's adjuvant.
Hood, Leroy E. +3 more
core +2 more sources
Recent Progress on Flexible Multimodal Sensors: Decoupling Strategies, Fabrication and Applications
Advanced Materials, EarlyView.In this review, we establish a tripartite decoupling framework for flexible multimodal sensors, which elucidates the underlying principles of signal crosstalk and their solutions through material design, structural engineering, and AI algorithms. We also demonstrate its potential applications across environmental monitoring, health monitoring, human ...
Tao Wu +10 more
wiley +1 more source
Frontiers in Immunology, 2011 T cell receptor (TCR) recognition is intrinsically polyspecific. In the field of autoimmunity, recognition of both self- and microbial peptides by a single TCR has led to the concept of molecular mimicry.
Roland S. LIBLAU
doaj +1 more source
Nanoclustering as a dominant feature of plasma membrane organization [PDF]
, 2014 Early studies have revealed that some mammalian plasma membrane proteins exist in small nanoclusters. The advent of super-resolution microscopy has corroborated and extended this picture, and led to the suggestion that many, if not most, membrane ...
Cambi, Alessandra +4 more
core +5 more sources
Advanced Materials Interfaces, EarlyView.Here, we present a nanotechnology approach to construct synthetic lipid rafts on the live T cell membrane, leveraging a versatile DNA origami‐enabled platform named as the “cholesterol nano‐patch” (CNP). Our investigation highlights the effectiveness of DNA nanotechnology in exploring the impact of nanoscale arrangement of cholesterols on the ...
Yunmin Jung +4 more
wiley +1 more source
An old twist in HLA-A: CDR3 alpha hook up at an R65-joint
Frontiers in Immunology, 2015 T-cell ontogeny optimizes the alpha/beta T-cell receptor (TCR) repertoire for recognition of major histocompatibility complex (MHC) class-I/-II genetic polymorphism; and co-evolution of TCR germline V-gene segments and the MHC must entail somatic ...
Joseph eMurray
doaj +1 more source