Results 221 to 230 of about 34,505 (262)

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Correction to "The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression". [PDF]

Nat Commun
Xu M, Ito-Kureha T, Kang HS, Chernev A, Raj T, Hoefig KP, Hohn C, Giesert F, Wang Y, Pan W, Ziętara N, Straub T, Feederle R, Daniel C, Adler B, König J, Feske S, Tsokos GC, Wurst W, Urlaub H, Sattler M, Kisielow J, Wulczyn FG, Łyszkiewicz M, Heissmeyer V.   +24 more
europepmc   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression. [PDF]

Nat Commun
Xu M, Ito-Kureha T, Kang HS, Chernev A, Raj T, Hoefig KP, Hohn C, Giesert F, Wang Y, Pan W, Ziętara N, Straub T, Feederle R, Daniel C, Adler B, König J, Feske S, Tsokos GC, Wurst W, Urlaub H, Sattler M, Kisielow J, Wulczyn FG, Łyszkiewicz M, Heissmeyer V.   +24 more
europepmc   +1 more source

TCR sequencing and cloning methods for repertoire analysis and isolation of tumor-reactive TCRs [PDF]

Cell Reports Methods, 2023
T cell receptor (TCR) technologies, including repertoire analyses and T cell engineering, are increasingly important in the clinical management of cellular immunity in cancer, transplantation, and other immune diseases. However, sensitive and reliable methods for repertoire analyses and TCR cloning are still lacking.
Alexandra Michel, Patrick Reichenbach, Julien Schmidt   +2 more
exaly   +4 more sources

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TCR-beta repertoire development in the mouse embryo

The Journal of Immunology, 1997
Abstract We studied the TCR beta-chain repertoire in thymocytes along embryonic development. At day 14 of gestation, complete V-D-J rearrangements of the TCR-beta locus were detected at the messenger RNA level, and a total of 56 different rearrangements were observed in one thymus.
H, Ema, A, Cumano, P, Kourilsky
openaire   +2 more sources

TCR repertoire in early fetal mouse thymus

International Immunology, 1995
We investigated the rearrangement and expression of TCR genes in mouse fetal thymus organ culture, a system that avoids subsequent entry of hematopoietic precursor cells. The first observable rearranged TCR gene was homogeneous V gamma 2-J gamma 2, detectable as early as fetal day 11 (d11) in the thymic primordia.
H, Ohki-Hamazaki, Y, Makino, M, Kanno, H, Koseki, T, Akasaka, M, Taniguchi   +5 more
openaire   +2 more sources

Individuality of Ag-Selected and Preimmune TCR Repertoires

Immunologic Research, 2001
We have combined flow cytometry and single-cell PCR to characterize the TCRBV repertoires selected by individual mice in a model CD8 response against a defined peptide/MHC complex (CW3 170-1 79/Kd). Ourresults established thatdifferent mice select individually distinct yet structurally similar CW3-specific repertoires.
J L, Maryanski, V, Attuil, A, Hamrouni, M, Mutin, M, Rossi, A, Aublin, P, Bucher   +6 more
openaire   +2 more sources

Chronic Modulation of the TCR Repertoire in the Lymphoid Periphery

The Journal of Immunology, 1999
Abstract Using TCR Vβ5 transgenic mice as a model system, we demonstrate that the induction of peripheral tolerance can mold the TCR repertoire throughout adult life. In these mice, three distinct populations of peripheral T cells are affected by chronic selective events in the lymphoid periphery.
C A, Blish, B J, Gallay, G L, Turk, K M, Kline, W, Wheat, P J, Fink   +5 more
openaire   +2 more sources