TCR Repertoire Analysis Unveils the Link Between Kawasaki Disease and Viral Infection. [PDF]
BiomedicinesGeng Z +8 more
europepmc +1 more source
A Novel CDC42 Variant with Impaired Thymopoiesis, IL-7R Signaling, PAK1 Binding, and TCR Repertoire Diversity. [PDF]
J Clin Immunol, 2023 Assing K +15 more
europepmc +1 more source
Decoding immune‐driven erythroid failure in pure red cell aplasia
British Journal of Haematology, Volume 208, Issue 5, Page 1887-1889, May 2026.Pure red cell aplasia (PRCA) is increasingly recognised as a T‐cell‐mediated bone marrow failure syndrome, yet its immunogenetic drivers remain poorly defined. In their paper, Yamashita et al. integrate human leucocyte antigen (HLA) typing, T‐cell receptor repertoire analysis and mutational profiling to reveal enriched HLA alleles, signal transducer ...
Federico Spataro +2 more
wiley +1 more source
British Journal of Haematology, Volume 208, Issue 5, Page 1797-1805, May 2026.Summary T‐cell abnormalities have been implicated in the pathogenesis of acquired pure red cell aplasia (PRCA), particularly in its major subtypes such as idiopathic PRCA, thymoma‐associated PRCA and large granular lymphocytic leukaemia (LGLL)–associated PRCA, and the precise details remain unclear.
Naruaki Yamashita +11 more
wiley +1 more source
Spatiotemporal commonality of the TCR repertoire in a T-cell memory murine model and in metastatic human colorectal cancer. [PDF]
Cancer Immunol Immunother, 2023 Haraguchi M +9 more
europepmc +1 more source
Requirement of full TCR repertoire for regulatory T cells to maintain intestinal homeostasis [PDF]
, 2015 Junko Nishio +9 more
openalex +1 more source
Why Is MS a More Frequent Complication of EBV Infection in Females?
Immunological Reviews, Volume 339, Issue 1, May 2026.ABSTRACT Multiple sclerosis (MS) is a T helper (Th) cell‐mediated disease that targets central nervous system (CNS) white matter. This disease affects three times more females than males. For many years, the etiology of MS was not well understood and the exact nature of the autoimmune reaction was speculative.
Shannon E. Dunn +2 more
wiley +1 more source
Analyzing the CDR3 Repertoire with respect to TCR—Beta Chain V-D-J and V-J Rearrangements in Peripheral T Cells using HTS [PDF]
, 2016 Long Ma +9 more
openalex +1 more source
From Development to Aging: Dynamic Roles of the Thymic Medulla in T Cell Biology
Immunological Reviews, Volume 339, Issue 1, May 2026.ABSTRACT The thymic medulla is essential for establishing central tolerance, orchestrating the development of a diverse yet self‐tolerant T cell repertoire, and preventing autoimmunity. This process is primarily mediated through interactions between developing thymocytes and antigen‐presenting cells, including thymic epithelial cells (TECs) and ...
Christina Michalaki +2 more
wiley +1 more source