Results 181 to 190 of about 34,505 (262)

Chain-specific remodeling of the γδ T-cell TCR repertoire in preterm infants with cCMV: a gestational-age-stratified case-control study. [PDF]

Front Immunol
Liu P, Zou R, Zhao J, Zhang Y, Liu Y, Tang P, Wu K, Gao X.   +7 more
europepmc   +1 more source

TCR repertoire landscape reveals macrophage-mediated clone deletion in endotoxin tolerance. [PDF]

Inflamm Res, 2023
Zhao J, Jia L, Tao Y, Zhao X, Yang J, Lu Y, Yan Y, Mao L, Hu L, Lu J, Guo M, Chen C, Zhou Y, Wen Z, He Z, Xu L.   +15 more
europepmc   +1 more source

Distinct landscapes of T-cell immunity and TCR repertoire between sepsis and pre-septic high-risk states. [PDF]

Front Immunol
Ma Y, Shen S, Zheng W, Liu M, Yang X, Wang Y, Zhang X.   +6 more
europepmc   +1 more source

Evaluation of the TCR Repertoire as a Predictive and Prognostic Biomarker in Cancer: Diversity or Clonality? [PDF]

Cancers (Basel), 2022
Aran A, Garrigós L, Curigliano G, Cortés J, Martí M.   +4 more
europepmc   +1 more source

Regulation of Immune Checkpoints: From Molecular Mechanisms to Clinical Therapies

MedComm, Volume 7, Issue 6, June 2026.
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by unleashing antitumor immunity. This review comprehensively examines the molecular mechanisms underlying key immune checkpoints—including PD‐1/PD‐L1, CTLA‐4, and TIM‐3—and their clinical applications.
Qintao Ge, Liu Yu, Jiahe Lu, Aihetaimujiang Anwaier, Xiyue Xiao, Yonghao Chen, Dingwei Ye, Hailiang Zhang, Wenhao Xu, Wenbin Dai   +9 more
wiley   +1 more source

TCR repertoire of human cytotoxic CD4 T cells responding to betaherpesviruses HHV-6B and HCMV. [PDF]

Front Immunol
Becerra-Artiles A, Weaver GC, Oluoch PO, Stern LJ.   +3 more
europepmc   +1 more source

Lower TCR repertoire diversity in Traj18-deficient mice [PDF]

Nature Immunology, 2012
Romain, Bedel, Jennifer L, Matsuda, Manfred, Brigl, Janice, White, John, Kappler, Philippa, Marrack, Laurent, Gapin   +6 more
openaire   +2 more sources

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source

The Tumor Immune Microenvironment in Endometrial Cancer: Composition, Molecular Subtypes, and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Endometrial cancer (EC), a major gynecologic malignancy and a representative “cold tumor”, exhibits a tumor immune microenvironment (TIME) influenced by a broad range of cellular and molecular elements, immunosuppressive signals, and pathways of immune evasion.
Jingxuan Ye, Yashi Shi, Alexander Mustea, Xiaodan Mao, Pengming Sun   +4 more
wiley   +1 more source

Radiotherapy-activated NBTXR3 nanoparticles modulate cancer cell immunogenicity and TCR repertoire. [PDF]

Cancer Cell Int, 2022
Darmon A, Zhang P, Marill J, Mohamed Anesary N, Da Silva J, Paris S.   +5 more
europepmc   +1 more source