Results 181 to 190 of about 206,427 (253)

Discovery of Post‐Translationally Modified Epitopes in Autoimmunity: Someone Has to Fish so Everyone Can Eat

Immunological Reviews, Volume 343, Issue 1, October 2026.
ABSTRACT Post‐translational modifications (PTMs) chemically diversify the ~20,000 genomically encoded proteins into millions of functional variants, and this diversity has profound consequences for T cell‐mediated immune responses. PTM‐reactive T cells have been identified across numerous autoimmune diseases and, in several cases, implicated directly ...
Sanya Arshad, Benjamin M. Cameron, Alok V. Joglekar   +2 more
wiley   +1 more source

Longitudinal TCR repertoire profiling predicts refractory cytomegalovirus reactivation after haploidentical hematopoietic stem cell transplantation. [PDF]

Virol J
Yuan H, Liu L, Chen G, Xu J, Zhang K, Yang R, Han C, Hou J, Jiang M.   +8 more
europepmc   +1 more source

Human thymic putative CD8αα precursors exhibit a biased TCR repertoire in single cell AIRR-seq. [PDF]

Sci Rep, 2023
Heimli M, Tennebø Flåm S, Sagsveen Hjorthaug H, Bjørnstad PM, Chernigovskaya M, Le QK, Tekpli X, Greiff V, Lie BA.   +8 more
europepmc   +1 more source

Peptide‐Enabled Nanoplatforms for Malaria and Leishmaniasis: From Intracellular Targeting to Translational Diagnostic Perspectives

ChemMedChem, Volume 21, Issue 18, 28 September 2026.
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales, Ana Clara Lunardi Yagi, Túlio Custódio Reis, Jessica Ingrid Cazorla, Jade Rojas Villar, Marcia A. Graminha, Roxana Yesenia Pastrana Alta, Fernando Rogério Pavan   +7 more
wiley   +1 more source

Author Correction: Longitudinal single-cell and TCR repertoire profiling characterizes clonal entrapment in patients with pMMR/MSS locally advanced rectal cancer. [PDF]

Cell Discov
Tang Z, Zhu M, Zhao S, Pang D, Cui Y, Lin G, Wu A, Lin Y, Jiang X, Zhang W, Xiong N, Yang C, Wang C, Wang S, Ye Y, Bai F, Shen Z.   +16 more
europepmc   +1 more source

Lower TCR repertoire diversity in Traj18-deficient mice [PDF]

Nature Immunology, 2012
Romain, Bedel, Jennifer L, Matsuda, Manfred, Brigl, Janice, White, John, Kappler, Philippa, Marrack, Laurent, Gapin   +6 more
openaire   +2 more sources

Superantigens in Cancer Immunotherapy: Mechanisms, Engineering Strategies, and Therapeutic Potential

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Schematic overview of superantigen‐mediated antitumor immune responses and immune suppression within the tumor microenvironment. (1) Antigen‐presenting cells activate T cells through MHC‐II/TCR interactions resulting in the production of cytokines (2) The pro‐inflammatory cytokines released by activated immune cells stimulate downstream immune ...
Urooj Yousaf Virk, Hafiza Aasia Malik, Muneera Anwer, Jennifer Wilson, Md. Sifat Rahi, Ming Q. Wei   +5 more
wiley   +1 more source

TIRTL-seq: deep, quantitative and affordable paired TCR repertoire sequencing. [PDF]

Nat Methods
Pogorelyy MV, Kirk AM, Adhikari S, Minervina AA, Sundararaman B, Vegesana K, Brice DC, Scott ZB, SJTRC Study Team, Thomas PG.   +9 more
europepmc   +1 more source

Tick-borne encephalitis virus variants drive distinct TCR repertoire alterations. [PDF]

Front Immunol
Salnikova MA, Tuchynskaya KK, Minervina AA, Pogorelyy MV, Okhezin EV, Karganova GG, Mamedov IZ, Lebedev YB.   +7 more
europepmc   +1 more source

Unique features of the TCR repertoire of reactivated memory T cells in the experimental mouse tumor model. [PDF]

Comput Struct Biotechnol J, 2023
Kalinina A, Persiyantseva N, Britanova O, Lupyr K, Shagina I, Khromykh L, Kazansky D.   +6 more
europepmc   +1 more source