Results 191 to 200 of about 206,427 (253)

Longitudinal single-cell and TCR repertoire profiling characterizes clonal entrapment in patients with pMMR/MSS locally advanced rectal cancer. [PDF]

Cell Discov
Tang Z, Zhu M, Zhao S, Pang D, Cui Y, Lin G, Wu A, Lin Y, Jiang X, Zhang W, Xiong N, Yang C, Wang C, Wang S, Ye Y, Bai F, Shen Z.   +16 more
europepmc   +1 more source

A Novel CDC42 Variant with Impaired Thymopoiesis, IL-7R Signaling, PAK1 Binding, and TCR Repertoire Diversity. [PDF]

J Clin Immunol, 2023
Assing K, Jørgensen SE, Sandgaard KS, De Keukeleere K, B-Hansen M, Petersen MS, Hartling UB, Vaal TMK, Nielsen C, Jakobsen MA, Watt E, Adams S, Hao Q, Fagerberg C, Mogensen TH, Mogensen TH.   +15 more
europepmc   +1 more source

Clonal reshaping and clinical outcomes after rechallenge in ICI-associated myocarditis: integrated single-cell and TCR repertoire analysis. [PDF]

J Immunother Cancer
Zhang J, He X, Zhang Y, Qian X, Song Y, Zhang S, Li Z, Wang Z, Lu B, Cai Q, Cheng L, Wang Y.   +11 more
europepmc   +1 more source

Spatiotemporal commonality of the TCR repertoire in a T-cell memory murine model and in metastatic human colorectal cancer. [PDF]

Cancer Immunol Immunother, 2023
Haraguchi M, Kiyotani K, Tate T, Sakata S, Sagawa R, Takagi S, Nagayama S, Takeuchi K, Takahashi K, Katayama R.   +9 more
europepmc   +1 more source

Chain-specific remodeling of the γδ T-cell TCR repertoire in preterm infants with cCMV: a gestational-age-stratified case-control study. [PDF]

Front Immunol
Liu P, Zou R, Zhao J, Zhang Y, Liu Y, Tang P, Wu K, Gao X.   +7 more
europepmc   +1 more source

TCR repertoire landscape reveals macrophage-mediated clone deletion in endotoxin tolerance. [PDF]

Inflamm Res, 2023
Zhao J, Jia L, Tao Y, Zhao X, Yang J, Lu Y, Yan Y, Mao L, Hu L, Lu J, Guo M, Chen C, Zhou Y, Wen Z, He Z, Xu L.   +15 more
europepmc   +1 more source

Case Report: Long-term TCR repertoire dynamics in a disease-free survival stage IIIB-N3 lung adenocarcinoma patient treated with anti-PD-1 followed by surgery. [PDF]

Front Immunol
Zhai X, Liu Y, Wang M, Liu Z, Huang K, Wu X, Fan M, Huang Y, Gu X, Liu J, Cai X, Wang Y, Jiang L, Zhu D.   +13 more
europepmc   +1 more source

Distinct landscapes of T-cell immunity and TCR repertoire between sepsis and pre-septic high-risk states. [PDF]

Front Immunol
Ma Y, Shen S, Zheng W, Liu M, Yang X, Wang Y, Zhang X.   +6 more
europepmc   +1 more source

TCR repertoire of human cytotoxic CD4 T cells responding to betaherpesviruses HHV-6B and HCMV. [PDF]

Front Immunol
Becerra-Artiles A, Weaver GC, Oluoch PO, Stern LJ.   +3 more
europepmc   +1 more source

TCR Repertoire: Metrics, Structure and Clinical Implementation

The T-cell receptor (TCR) repertoire is continuously molded by immunological challenges, including pathogen exposure, tumor recognition, and hematological diseases: each influencing its diversity and clonality. Characterizing the structure and evolutionary dynamics of TCR repertoires provides critical insight into immune system function, persistence of
openaire   +1 more source